| Literature DB >> 12591570 |
Shantanu Sarkar1, Keith Heberlein, Xiaoping Hu.
Abstract
Truncation artifacts arise in magnetic resonance spectroscopic imaging (MRSI) of the human brain due to limited coverage of k-space necessitated by low SNR of metabolite signal and limited scanning time. In proton MRSI of the head, intense extra-cranial lipid signals "bleed" into brain regions, thereby contaminating signals of metabolites therein. This work presents a data acquisition strategy for reducing truncation artifact based on extended k-space coverage achieved with a dual-SNR strategy. Using the fact that the SNR in k-space increases monotonically with sampling density, dual-SNR is achieved in an efficient manner with a dual-density spiral k-space trajectory that permits a smooth transition from high density to low density. The technique is demonstrated to be effective in reducing "bleeding" of extra-cranial lipid signals while preserving the SNR of metabolites in the brain.Entities:
Mesh:
Year: 2002 PMID: 12591570 DOI: 10.1016/s0730-725x(02)00608-2
Source DB: PubMed Journal: Magn Reson Imaging ISSN: 0730-725X Impact factor: 2.546