Literature DB >> 12564470

Synthesis antimicrobial and antifungal activity of some new 3 substituted derivatives of 4-(2,4-dichlorophenyl)-5-adamantyl-1H-1,2,4-triazole.

S Papakonstantinou-Garoufalias1, N Pouli, P Marakos, A Chytyroglou-Ladas.   

Abstract

The synthesis of a series of substituted hydrazones and thiazolidinones is described, starting from N-[4-(2,4-dichlorophenyl)-5-adamantyl-1H-1,2,4-triazol-3-ylmercaptoacetyl]hydrazine. The new compounds were tested for antimicrobial and antifungal activity and some of them exhibited moderate activity against Candida albicans.

Entities:  

Mesh:

Substances:

Year:  2002        PMID: 12564470     DOI: 10.1016/s0014-827x(02)01227-2

Source DB:  PubMed          Journal:  Farmaco        ISSN: 0014-827X


  9 in total

1.  In vivo metabolism of 2-[1'-phenyl-3'-(3-chlorophenyl)-2'-propenylyden]hydrazino-3-methyl-4(3H)-quinazolinone in rats.

Authors:  Bedia Koçyiğit Kaymakçioğlu; Yasemin Aktan; Sibel Süzen; Nesrin Gökhan; Semra Koyunoğlu; Kevser Erol; Akgül Yeşilada; Sevim Rollas
Journal:  Eur J Drug Metab Pharmacokinet       Date:  2005 Oct-Dec       Impact factor: 2.441

2.  Study of Binding Properties Between Two New Ibuprofen and Naproxen Based Acyl Hydrazone Derivatives and Trypsin.

Authors:  Elmas Gökoğlu; Esra Yılmaz; Esra Gökoğlu; Ayşe Uzgören Baran
Journal:  J Fluoresc       Date:  2016-01       Impact factor: 2.217

3.  HPLC analysis of in vivo metabolites of 4-nitrobenzoic acid [(5-nitro-2-thiopheneyl)methylene]hydrazide in rats.

Authors:  Bedia Koçyiğit-Kaymakçioğlu; Seda Unsalan; S Güniz Küçükgüzel; Göksel Sener; Sevim Rollas
Journal:  Eur J Drug Metab Pharmacokinet       Date:  2007 Oct-Dec       Impact factor: 2.441

4.  2-[4-(4-Methoxy-phen-yl)-5-(2-pyrid-yl)-4H-1,2,4-triazol-3-yl]phenol.

Authors:  Mei-An Zhu; Zhao-Di Liu; Shu-Ping Zhang; Ying Wei; Si-Chang Shao
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2009-06-27

5.  (1E,2E)-1,2-Bis[1-(2-methoxy-phen-yl)ethyl-idene]hydrazine.

Authors:  Suchada Chantrapromma; Patcharaporn Jansrisewangwong; Hoong-Kun Fun
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2010-10-31

6.  Radioprotective effect of sulphydryl group containing triazole derivative to modulate the radiation- induced clastogenic effects.

Authors:  L N Madhu; N S Kumari
Journal:  Res Pharm Sci       Date:  2014 Jan-Feb

7.  Crystal structure of two N'-(1-phenyl-benzyl-idene)-2-(thio-phen-3-yl)acetohydrazides.

Authors:  Trung Vu Quoc; Linh Nguyen Ngoc; Duong Tran Thi Thuy; Manh Vu Quoc; Thien Vuong Nguyen; Yen Oanh Doan Thi; Luc Van Meervelt
Journal:  Acta Crystallogr E Crystallogr Commun       Date:  2019-07-02

8.  Optimized Synthesis of New Thiosemicarbazide Derivatives with Tuberculostatic Activity.

Authors:  Corina Popovici; Cristina-Maria Pavel; Valeriu Sunel; Corina Cheptea; Dan Gheorghe Dimitriu; Dana Ortansa Dorohoi; Diana David; Valentina Closca; Marcel Popa
Journal:  Int J Mol Sci       Date:  2021-11-09       Impact factor: 5.923

9.  A new polymorph of N-(2-{N'-[(1E)-2-hy-droxy-benzyl-idene]hydrazinecarbon-yl}phen-yl)benzamide.

Authors:  Shaaban K Mohamed; Joel T Mague; Mehmet Akkurt; Herman Potgieter; Mustafa R Albayati
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2014-05-10
  9 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.