Literature DB >> 12438432

Deciphering the genesis and fate of amyloid beta-protein yields novel therapies for Alzheimer disease.

Dennis J Selkoe1.   

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Year:  2002        PMID： 12438432      PMCID： PMC151820          DOI： 10.1172/JCI16783

Source DB:  PubMed          Journal:  J Clin Invest        ISSN： 0021-9738            Impact factor:   14.808


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  64 in total

Review 1.  Abeta-generating enzymes: recent advances in beta- and gamma-secretase research.

Authors:  R Vassar; M Citron
Journal:  Neuron       Date:  2000-09       Impact factor: 17.173

2.  Requirements for presenilin-dependent cleavage of notch and other transmembrane proteins.

Authors:  G Struhl; A Adachi
Journal:  Mol Cell       Date:  2000-09       Impact factor: 17.970

3.  Peripherally administered antibodies against amyloid beta-peptide enter the central nervous system and reduce pathology in a mouse model of Alzheimer disease.

Authors:  F Bard; C Cannon; R Barbour; R L Burke; D Games; H Grajeda; T Guido; K Hu; J Huang; K Johnson-Wood; K Khan; D Kholodenko; M Lee; I Lieberburg; R Motter; M Nguyen; F Soriano; N Vasquez; K Weiss; B Welch; P Seubert; D Schenk; T Yednock
Journal:  Nat Med       Date:  2000-08       Impact factor: 53.440

4.  Nasal administration of amyloid-beta peptide decreases cerebral amyloid burden in a mouse model of Alzheimer's disease.

Authors:  H L Weiner; C A Lemere; R Maron; E T Spooner; T J Grenfell; C Mori; S Issazadeh; W W Hancock; D J Selkoe
Journal:  Ann Neurol       Date:  2000-10       Impact factor: 10.422

5.  Transition-state analogue inhibitors of gamma-secretase bind directly to presenilin-1.

Authors:  W P Esler; W T Kimberly; B L Ostaszewski; T S Diehl; C L Moore; J Y Tsai; T Rahmati; W Xia; D J Selkoe; M S Wolfe
Journal:  Nat Cell Biol       Date:  2000-07       Impact factor: 28.824

6.  Glycine 384 is required for presenilin-1 function and is conserved in bacterial polytopic aspartyl proteases.

Authors:  H Steiner; M Kostka; H Romig; G Basset; B Pesold; J Hardy; A Capell; L Meyn; M L Grim; R Baumeister; K Fechteler; C Haass
Journal:  Nat Cell Biol       Date:  2000-11       Impact factor: 28.824

7.  The oligomerization of amyloid beta-protein begins intracellularly in cells derived from human brain.

Authors:  D M Walsh; B P Tseng; R E Rydel; M B Podlisny; D J Selkoe
Journal:  Biochemistry       Date:  2000-09-05       Impact factor: 3.162

Review 8.  Tau mutations in frontotemporal dementia FTDP-17 and their relevance for Alzheimer's disease.

Authors:  M Goedert; M G Spillantini
Journal:  Biochim Biophys Acta       Date:  2000-07-26

9.  Deficiency of presenilin-1 inhibits the normal cleavage of amyloid precursor protein.

Authors:  B De Strooper; P Saftig; K Craessaerts; H Vanderstichele; G Guhde; W Annaert; K Von Figura; F Van Leuven
Journal:  Nature       Date:  1998-01-22       Impact factor: 49.962

10.  Evidence for genetic linkage of Alzheimer's disease to chromosome 10q.

Authors:  L Bertram; D Blacker; K Mullin; D Keeney; J Jones; S Basu; S Yhu; M G McInnis; R C Go; K Vekrellis; D J Selkoe; A J Saunders; R E Tanzi
Journal:  Science       Date:  2000-12-22       Impact factor: 47.728
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  65 in total

Review 1.  Protein aggregation in disease: a role for folding intermediates forming specific multimeric interactions.

Authors:  Arthur Horwich
Journal:  J Clin Invest       Date:  2002-11       Impact factor: 14.808

2.  The cellular response to aggregated proteins associated with human disease.

Authors:  David H Perlmutter
Journal:  J Clin Invest       Date:  2002-11       Impact factor: 14.808

3.  Identification of small molecule inhibitors of neurite loss induced by Aβ peptide using high content screening.

Authors:  Dimitry Ofengeim; Peng Shi; Benchun Miao; Jing Fan; Xiaofeng Xia; Yubo Fan; Marta M Lipinski; Tadafumi Hashimoto; Manuela Polydoro; Junying Yuan; Stephen T C Wong; Alexei Degterev
Journal:  J Biol Chem       Date:  2012-01-25       Impact factor: 5.157

Review 4.  Divide and die: cell cycle events as triggers of nerve cell death.

Authors:  Karl Herrup; Rachael Neve; Susan L Ackerman; Agata Copani
Journal:  J Neurosci       Date:  2004-10-20       Impact factor: 6.167

5.  A statistical-mechanical theory of fibril formation in dilute protein solutions.

Authors:  Jeroen van Gestel; Simon W de Leeuw
Journal:  Biophys J       Date:  2006-05-01       Impact factor: 4.033

Review 6.  GroEL-mediated protein folding: making the impossible, possible.

Authors:  Zong Lin; Hays S Rye
Journal:  Crit Rev Biochem Mol Biol       Date:  2006 Jul-Aug       Impact factor: 8.250

7.  Heparan sulphate proteoglycan and the low-density lipoprotein receptor-related protein 1 constitute major pathways for neuronal amyloid-beta uptake.

Authors:  Takahisa Kanekiyo; Juan Zhang; Qiang Liu; Chia-Chen Liu; Lijuan Zhang; Guojun Bu
Journal:  J Neurosci       Date:  2011-02-02       Impact factor: 6.167

8.  Cytokine production by a human microglial cell line: effects of beta-amyloid and alpha-melanocyte-stimulating hormone.

Authors:  Catharina Lindberg; Erik Hjorth; Claes Post; Bengt Winblad; Marianne Schultzberg
Journal:  Neurotox Res       Date:  2005-11       Impact factor: 3.911

9.  5-Lipoxygenase gene disruption reduces amyloid-beta pathology in a mouse model of Alzheimer's disease.

Authors:  Omidreza Firuzi; Jiamin Zhuo; Cinzia M Chinnici; Thomas Wisniewski; Domenico Praticò
Journal:  FASEB J       Date:  2007-11-12       Impact factor: 5.191

10.  Mild cognitive impairment: searching for the prodrome of Alzheimer's disease.

Authors:  Paul B Rosenberg; Constantine Lyketsos
Journal:  World Psychiatry       Date:  2008       Impact factor: 49.548
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