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1. Proteolysis in Alzheimer's disease. Can plasmin tip the balance?

Authors: G Periz; M E Fortini
Journal: EMBO Rep Date: 2000-12 Impact factor: 8.807

Review 2. Recent advances: Psychiatry.

Authors: D Lyons; D M McLoughlin
Journal: BMJ Date: 2001-11-24

3. The intramembrane cleavage site of the amyloid precursor protein depends on the length of its transmembrane domain.

Authors: Stefan F Lichtenthaler; Dirk Beher; Heike S Grimm; Rong Wang; Mark S Shearman; Colin L Masters; Konrad Beyreuther
Journal: Proc Natl Acad Sci U S A Date: 2002-01-22 Impact factor: 11.205

4. The gamma -secretase-cleaved C-terminal fragment of amyloid precursor protein mediates signaling to the nucleus.

Authors: Y Gao; S W Pimplikar
Journal: Proc Natl Acad Sci U S A Date: 2001-12-11 Impact factor: 11.205

5. Notch receptor cleavage depends on but is not directly executed by presenilins.

Authors: Yoshihito Taniguchi; Helena Karlström; Johan Lundkvist; Tomohiko Mizutani; Akira Otaka; Monica Vestling; Alan Bernstein; Dorit Donoviel; Urban Lendahl; Tasuku Honjo
Journal: Proc Natl Acad Sci U S A Date: 2002-03-12 Impact factor: 11.205

Review 6. Spotlight on BACE: the secretases as targets for treatment in Alzheimer disease.

Authors: C Dingwall
Journal: J Clin Invest Date: 2001-11 Impact factor: 14.808

7. Presenilin and nicastrin regulate each other and determine amyloid beta-peptide production via complex formation.

Authors: Dieter Edbauer; Edith Winkler; Christian Haass; Harald Steiner
Journal: Proc Natl Acad Sci U S A Date: 2002-06-04 Impact factor: 11.205

Review 8. Deciphering the genesis and fate of amyloid beta-protein yields novel therapies for Alzheimer disease.

Authors: Dennis J Selkoe
Journal: J Clin Invest Date: 2002-11 Impact factor: 14.808

9. A gamma-secretase inhibitor blocks Notch signaling in vivo and causes a severe neurogenic phenotype in zebrafish.

Authors: Andrea Geling; Harald Steiner; Michael Willem; Laure Bally-Cuif; Christian Haass
Journal: EMBO Rep Date: 2002-07 Impact factor: 8.807

10. gamma-Secretase substrate selectivity can be modulated directly via interaction with a nucleotide-binding site.

Authors: Patrick C Fraering; Wenjuan Ye; Matthew J LaVoie; Beth L Ostaszewski; Dennis J Selkoe; Michael S Wolfe
Journal: J Biol Chem Date: 2005-10-19 Impact factor: 5.157