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Literature DB >> 12386335

Tech.Sight. Phage display. Affinity selection from biological libraries.

James F Smothers¹, Steven Henikoff, Paul Carter.

Abstract

Phage display is a simple yet powerful technology that is used to rapidly characterize protein-protein interactions from amongst billions of candidates. This widely practiced technique is used to map antibody epitopes, create vaccines and to engineer peptides, antibodies and other proteins as both diagnostic tools and as human therapeutics. We overview the history of phage display and several recent applications.

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Year: 2002 PMID： 12386335 DOI： 10.1126/science.298.5593.621

Source DB: PubMed Journal: Science ISSN： 0036-8075 Impact factor: 47.728

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Cited

23 in total

1. A novel helper phage that improves phage display selection efficiency by preventing the amplification of phages without recombinant protein.

Authors: R Arjen Kramer; Freek Cox; Marieke van der Horst; Sonja van der Oudenrijn; Pieter C M Res; Judith Bia; Ton Logtenberg; John de Kruif
Journal: Nucleic Acids Res Date: 2003-06-01 Impact factor: 16.971

2. Self-made phage libraries with heterologous inserts in the Mtd of Bordetella bronchiseptica.

Authors: Cathie M Overstreet; Tom Z Yuan; Aron M Levin; Calvin Kong; John G Coroneus; Gregory A Weiss
Journal: Protein Eng Des Sel Date: 2012-01-27 Impact factor: 1.650

3. A general method for greatly improving the affinity of antibodies by using combinatorial libraries.

Authors: Arvind Rajpal; Nurten Beyaz; Lauric Haber; Guido Cappuccilli; Helena Yee; Ramesh R Bhatt; Toshihiko Takeuchi; Richard A Lerner; Roberto Crea
Journal: Proc Natl Acad Sci U S A Date: 2005-06-06 Impact factor: 11.205

Review 4. Vaccinology in the genome era.

Authors: C Daniela Rinaudo; John L Telford; Rino Rappuoli; Kate L Seib
Journal: J Clin Invest Date: 2009-09 Impact factor: 14.808

10. Gene transduction and cell entry pathway of fiber-modified adenovirus type 5 vectors carrying novel endocytic peptide ligands selected on human tracheal glandular cells.

Authors: Florence Gaden; Laure Franqueville; Maria K Magnusson; Saw See Hong; Marc D Merten; Leif Lindholm; Pierre Boulanger
Journal: J Virol Date: 2004-07 Impact factor: 5.103

Tech.Sight. Phage display. Affinity selection from biological libraries.

1. A novel helper phage that improves phage display selection efficiency by preventing the amplification of phages without recombinant protein.

2. Self-made phage libraries with heterologous inserts in the Mtd of Bordetella bronchiseptica.

3. A general method for greatly improving the affinity of antibodies by using combinatorial libraries.

Review 4. Vaccinology in the genome era.

5. Biopanning Phage-Display Libraries on Small Tissue Sections Captured by Laser Capture Microdissection.

Review 6. Bacteriophages and medical oncology: targeted gene therapy of cancer.

Review 7. Virus-Derived Peptides for Clinical Applications.

8. Automated detection of conformational epitopes using phage display Peptide sequences.

9. The use of phage display to generate conformation-sensor recombinant antibodies.

10. Gene transduction and cell entry pathway of fiber-modified adenovirus type 5 vectors carrying novel endocytic peptide ligands selected on human tracheal glandular cells.