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Literature DB >> 12384377

TEM-103/IRT-28 beta-lactamase, a new TEM variant produced by Escherichia coli BM4511.

Rodrigo Alonso¹, Guy Gerbaud, Marc Galimand, Patrice Courvalin.

Abstract

Clinical isolate Escherichia coli BM4511 was resistant to broad-spectrum penicillins in the presence or in the absence of beta-lactamase inhibitors but remained susceptible to cephalosporins. Resistance was due to production of a new TEM-type beta-lactamase, designated TEM-103/IRT-28, characterized by the Arg(275)Leu substitution and encoded by the ca. 62-kb pIP845 conjugative plasmid of the IncI1 incompatibility group.

Entities: Chemical Gene Mutation Species

Mesh：

Substances：

Year: 2002 PMID： 12384377 PMCID： PMC128718 DOI： 10.1128/AAC.46.11.3627-3629.2002

Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN： 0066-4804 Impact factor: 5.191

18 in total

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Journal: Antimicrob Agents Chemother Date: 1990-11 Impact factor: 5.191

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Journal: Biochem J Date: 1991-05-15 Impact factor: 3.857

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Journal: Antimicrob Agents Chemother Date: 1999-07 Impact factor: 5.191

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Journal: Proc Natl Acad Sci U S A Date: 1978-08 Impact factor: 11.205

5. Effect of hyperproduction of TEM-1 beta-lactamase on in vitro susceptibility of Escherichia coli to beta-lactam antibiotics.

Authors: P J Wu; K Shannon; I Phillips
Journal: Antimicrob Agents Chemother Date: 1994-03 Impact factor: 5.191

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Authors: J R Knox
Journal: Antimicrob Agents Chemother Date: 1995-12 Impact factor: 5.191

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Journal: J Bacteriol Date: 1972-11 Impact factor: 3.490

8. Kanamycin-resistant vectors that are analogues of plasmids pUC8, pUC9, pEMBL8 and pEMBL9.

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Journal: Gene Date: 1986 Impact factor: 3.688

9. A novel complex mutant beta-lactamase, TEM-68, identified in a Klebsiella pneumoniae isolate from an outbreak of extended-spectrum beta-lactamase-producing Klebsiellae.

Authors: J Fiett; A Pałucha; B Miaczyńska; M Stankiewicz; H Przondo-Mordarska; W Hryniewicz; M Gniadkowski
Journal: Antimicrob Agents Chemother Date: 2000-06 Impact factor: 5.191

10. Molecular characterization of nine different types of mutants among 107 inhibitor-resistant TEM beta-lactamases from clinical isolates of Escherichia coli.

Authors: C Henquell; C Chanal; D Sirot; R Labia; J Sirot
Journal: Antimicrob Agents Chemother Date: 1995-02 Impact factor: 5.191

4 in total