Literature DB >> 22106220

Virulence factors and TEM-type β-lactamases produced by two isolates of an epidemic Klebsiella pneumoniae strain.

Frédéric Robin1, Claire Hennequin, Marek Gniadkowski, Racha Beyrouthy, Joanna Empel, Lucie Gibold, Richard Bonnet.   

Abstract

Two Klebsiella pneumoniae isolates of the same strain, identified in Poland, produced either TEM-47 or TEM-68, which differed by the Arg275Leu substitution. They harbored a few virulence factors, including an iron-chelating factor and capsule overproduction, suggesting that these factors were sufficient to enhance their nosocomial potency. TEM-68 and TEM-47 had similar enzymatic activities, but TEM-68 was less susceptible to inhibitors than TEM-47. These results confirm the role of the Arg275Leu substitution in the evolution of TEM enzymes.

Entities:  

Mesh：

Substances：

Year:  2011        PMID： 22106220      PMCID： PMC3264223          DOI： 10.1128/AAC.05079-11

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  39 in total

1.  Computerized microacidimetric determination of beta lactamase Michaelis-Menten constants.

Authors:  R Labia; J Andrillon; F Le Goffic
Journal:  FEBS Lett       Date:  1973-06-15       Impact factor: 4.124

2.  Prospective survey of colonization and infection caused by expanded-spectrum-beta-lactamase-producing members of the family Enterobacteriaceae in an intensive care unit.

Authors:  C De Champs; M P Sauvant; C Chanal; D Sirot; N Gazuy; R Malhuret; J C Baguet; J Sirot
Journal:  J Clin Microbiol       Date:  1989-12       Impact factor: 5.948

3.  Binding of the type 3 fimbriae of Klebsiella pneumoniae to human endothelial and urinary bladder cells.

Authors:  A M Tarkkanen; R Virkola; S Clegg; T K Korhonen
Journal:  Infect Immun       Date:  1997-04       Impact factor: 3.441

4.  A gene, uge, is essential for Klebsiella pneumoniae virulence.

Authors:  Miguel Regué; Beatriz Hita; Nuria Piqué; Luis Izquierdo; Susana Merino; Sandra Fresno; Vicente Javier Benedí; Juan M Tomás
Journal:  Infect Immun       Date:  2004-01       Impact factor: 3.441

5.  Molecular characterization and adhesive properties of CF29K, an adhesin of Klebsiella pneumoniae strains involved in nosocomial infections.

Authors:  P Di Martino; Y Bertin; J P Girardeau; V Livrelli; B Joly; A Darfeuille-Michaud
Journal:  Infect Immun       Date:  1995-11       Impact factor: 3.441

6.  Polysaccharide capsule-mediated resistance to opsonophagocytosis in Klebsiella pneumoniae.

Authors:  P Domenico; R J Salo; A S Cross; B A Cunha
Journal:  Infect Immun       Date:  1994-10       Impact factor: 3.441

7.  Sequential outbreaks of infection due to Klebsiella pneumoniae in a neonatal intensive care unit: implication of a conjugative R plasmid.

Authors:  S M Markowitz; J M Veazey; F L Macrina; C G Mayhall; V A Lamb
Journal:  J Infect Dis       Date:  1980-07       Impact factor: 5.226

8.  Mucoid phenotype of Klebsiella pneumoniae is a plasmid-encoded virulence factor.

Authors:  X Nassif; J M Fournier; J Arondel; P J Sansonetti
Journal:  Infect Immun       Date:  1989-02       Impact factor: 3.441

9.  Correlation of the virulence of Klebsiella pneumoniae K1 and K2 with the presence of a plasmid encoding aerobactin.

Authors:  X Nassif; P J Sansonetti
Journal:  Infect Immun       Date:  1986-12       Impact factor: 3.441

10.  A novel virulence gene in Klebsiella pneumoniae strains causing primary liver abscess and septic metastatic complications.

Authors:  Chi-Tai Fang; Yi-Ping Chuang; Chia-Tung Shun; Shan-Chwen Chang; Jin-Town Wang
Journal:  J Exp Med       Date:  2004-03-01       Impact factor: 14.307
View more
  3 in total

Review 1.  Correlation between antimicrobial resistance and virulence in Klebsiella pneumoniae.

Authors:  C Hennequin; F Robin
Journal:  Eur J Clin Microbiol Infect Dis       Date:  2015-12-30       Impact factor: 3.267

2.  Impact of therapy and strain type on outcomes in urinary tract infections caused by carbapenem-resistant Klebsiella pneumoniae.

Authors:  David van Duin; Eric Cober; Sandra S Richter; Federico Perez; Robert C Kalayjian; Robert A Salata; Scott Evans; Vance G Fowler; Keith S Kaye; Robert A Bonomo
Journal:  J Antimicrob Chemother       Date:  2014-12-09       Impact factor: 5.790

3.  Emergence of the third-generation cephalosporin-resistant hypervirulent Klebsiella pneumoniae due to the acquisition of a self-transferable blaDHA-1-carrying plasmid by an ST23 strain.

Authors:  Yingzhou Xie; Lijun Tian; Gang Li; Hongping Qu; Jingyong Sun; Wei Liang; Xiaobin Li; Xiaoli Wang; Zixin Deng; Jialin Liu; Hong-Yu Ou
Journal:  Virulence       Date:  2018-12-31       Impact factor: 5.882
  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.