Literature DB >> 1232029

The study of genic variation by electrophoretic and heat denaturation techniques at the octanol dehydrogenase locus in members of the Drosophila virilis group.

R S Singh, J L Hubby, L H Throckmorton.   

Abstract

Heat denaturation studies of three different electrophoretic allozymes of octanol dehydrogenase were performed from 10 species of the Drosophila virilis group. A total of 18 alleles were discovered, and in 3 species in which electrophoretic studies indicated that the locus was monomorphic, heat denaturation showed that the locus was polymorphic. We show that electrophoretic studies underestimate the number of alleles at this locus by a factor of 2.6 in these species. The results are discussed in the light of the continuing controversy over selection and neutral theories of genetic variation.

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Year:  1975        PMID: 1232029      PMCID: PMC1213365     

Source DB:  PubMed          Journal:  Genetics        ISSN: 0016-6731            Impact factor:   4.562


  7 in total

1.  THE NUMBER OF ALLELES THAT CAN BE MAINTAINED IN A FINITE POPULATION.

Authors:  M KIMURA; J F CROW
Journal:  Genetics       Date:  1964-04       Impact factor: 4.562

2.  An electrophoretic study of mutationally altered A proteins of the tryptophan synthetase of Escherichia coli.

Authors:  U HENNING; C YANOFSKY
Journal:  J Mol Biol       Date:  1963-01       Impact factor: 5.469

3.  Still more genetic variability in natural populations.

Authors:  S C Bernstein; L H Throckmorton; J L Hubby
Journal:  Proc Natl Acad Sci U S A       Date:  1973-12       Impact factor: 11.205

4.  Molecular heterosis for heat-sensitive enzyme alleles.

Authors:  R S Singh; J L Hubby; R C Lewontin
Journal:  Proc Natl Acad Sci U S A       Date:  1974-05       Impact factor: 11.205

5.  Stability and genetic variation of a structural protein.

Authors:  H Jockusch
Journal:  Naturwissenschaften       Date:  1968-11

6.  Polymorphisms in continental and island populations of Drosophila willistoni.

Authors:  F J Ayala; J R Powell; T Dobzhansky
Journal:  Proc Natl Acad Sci U S A       Date:  1971-10       Impact factor: 11.205

7.  Mutants of yeast defective in iso-1-cytochrome c.

Authors:  F Sherman; J W Stewart; M Jackson; R A Gilmore; J H Parker
Journal:  Genetics       Date:  1974-06       Impact factor: 4.562

  7 in total
  38 in total

1.  Alcohol dehydrogenase polymorphism in populations of Drosophila melanogaster. II. Relation between ADH activity and adult mortality.

Authors:  A Kamping; W van Delden
Journal:  Biochem Genet       Date:  1978-06       Impact factor: 1.890

2.  Hidden genetic variability within electromorphs in finite populations.

Authors:  R Chakraborty; M Nei
Journal:  Genetics       Date:  1976-10       Impact factor: 4.562

3.  Electrophoretically silent alleles in a finite population.

Authors:  M Nei; R Chakraborty
Journal:  J Mol Evol       Date:  1976-12-30       Impact factor: 2.395

4.  Allelic heterogeneity within allozymes separated by electrophoresis in Drosophila pseudoobscura.

Authors:  R E McDowell; S Prakash
Journal:  Proc Natl Acad Sci U S A       Date:  1976-11       Impact factor: 11.205

5.  Genetic differentiation studies and phylogenetic inference in the plant genus Limnanthes (section Inflexae).

Authors:  C I McNeill; S K Jain
Journal:  Theor Appl Genet       Date:  1983-09       Impact factor: 5.699

6.  Patterns of molecular variation. I. Interspecific comparisons of electromorphs in the Drosophila mulleri complex.

Authors:  R H Richardson; P E Smouse
Journal:  Biochem Genet       Date:  1976-06       Impact factor: 1.890

7.  Characterization of electrophoretically cryptic variation in the alpine butterfly Colias meadii.

Authors:  G B Johnson
Journal:  Biochem Genet       Date:  1977-08       Impact factor: 1.890

8.  The effects of overdominance of linkage in a multilocus system.

Authors:  T Yamazaki
Journal:  Genetics       Date:  1977-05       Impact factor: 4.562

9.  Further evidence of thermostability variation within electrophoretic mobility classes of enzymes.

Authors:  R Milkman
Journal:  Biochem Genet       Date:  1976-04       Impact factor: 1.890

10.  The purification and biochemical properties of alcohol dehydrogenase--"fast (Chateau Douglas)" from Drosophila melanogaster.

Authors:  G K Chambers
Journal:  Biochem Genet       Date:  1984-06       Impact factor: 1.890

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