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Literature DB >> 12234875

Gene dosage and linezolid resistance in Enterococcus faecium and Enterococcus faecalis.

S H Marshall¹, C J Donskey, R Hutton-Thomas, R A Salata, L B Rice.

Abstract

Resistance to linezolid has been associated with a G2576U mutation in domain V of the 23S rRNA. We analyzed nine clinical isolates of linezolid-resistant enterococci and showed a clear association between the number of 23S rRNA genes containing this mutation and the level of linezolid resistance expressed.

Entities: Chemical Species

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Year: 2002 PMID： 12234875 PMCID： PMC128780 DOI： 10.1128/AAC.46.10.3334-3336.2002

Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN： 0066-4804 Impact factor: 5.191

8 in total

1. Infections due to vancomycin-resistant Enterococcus faecium resistant to linezolid.

Authors: R D Gonzales; P C Schreckenberger; M B Graham; S Kelkar; K DenBesten; J P Quinn
Journal: Lancet Date: 2001-04-14 Impact factor: 79.321

2. Linezolid resistance in a clinical isolate of Staphylococcus aureus.

Authors: S Tsiodras; H S Gold; G Sakoulas; G M Eliopoulos; C Wennersten; L Venkataraman; R C Moellering; M J Ferraro
Journal: Lancet Date: 2001-07-21 Impact factor: 79.321

3. Resistance to linezolid: characterization of mutations in rRNA and comparison of their occurrences in vancomycin-resistant enterococci.

Authors: J Prystowsky; F Siddiqui; J Chosay; D L Shinabarger; J Millichap; L R Peterson; G A Noskin
Journal: Antimicrob Agents Chemother Date: 2001-07 Impact factor: 5.191

4. A polyclonal outbreak of predominantly VanB vancomycin-resistant enterococci in northeast Ohio. Northeast Ohio Vancomycin-Resistant Enterococcus Surveillance Program.

Authors: C J Donskey; J R Schreiber; M R Jacobs; R Shekar; R A Salata; S Gordon; C C Whalen; F Smith; L B Rice
Journal: Clin Infect Dis Date: 1999-09 Impact factor: 9.079

5. Resistance mutations in 23 S rRNA identify the site of action of the protein synthesis inhibitor linezolid in the ribosomal peptidyl transferase center.

Authors: P Kloss; L Xiong; D L Shinabarger; A S Mankin
Journal: J Mol Biol Date: 1999-11-19 Impact factor: 5.469

6. Diversity of domain V of 23S rRNA gene sequence in different Enterococcus species.

Authors: S Tsiodras; H S Gold; E P Coakley; C Wennersten; R C Moellering; G M Eliopoulos
Journal: J Clin Microbiol Date: 2000-11 Impact factor: 5.948

7. Mechanism of action of oxazolidinones: effects of linezolid and eperezolid on translation reactions.

Authors: D L Shinabarger; K R Marotti; R W Murray; A H Lin; E P Melchior; S M Swaney; D S Dunyak; W F Demyan; J M Buysse
Journal: Antimicrob Agents Chemother Date: 1997-10 Impact factor: 5.191

8. Genetic linkage and cotransfer of a novel, vanB-containing transposon (Tn5382) and a low-affinity penicillin-binding protein 5 gene in a clinical vancomycin-resistant Enterococcus faecium isolate.

Authors: L L Carias; S D Rudin; C J Donskey; L B Rice
Journal: J Bacteriol Date: 1998-09 Impact factor: 3.490

8 in total

76 in total

Review 1. Resistance to linezolid caused by modifications at its binding site on the ribosome.

Authors: Katherine S Long; Birte Vester
Journal: Antimicrob Agents Chemother Date: 2011-12-05 Impact factor: 5.191

2. Rapid detection and estimation by pyrosequencing of 23S rRNA genes with a single nucleotide polymorphism conferring linezolid resistance in Enterococci.

Authors: Alistair Sinclair; Catherine Arnold; Neil Woodford
Journal: Antimicrob Agents Chemother Date: 2003-11 Impact factor: 5.191

3. Clinical-use-associated decrease in susceptibility of vancomycin-resistant Enterococcus faecium to linezolid: a comparison with quinupristin-dalfopristin.

Authors: Issam I Raad; Hend A Hanna; Ray Y Hachem; Tanya Dvorak; Rebecca B Arbuckle; Gassan Chaiban; Louis B Rice
Journal: Antimicrob Agents Chemother Date: 2004-09 Impact factor: 5.191

4. Mutations in 23S rRNA at the peptidyl transferase center and their relationship to linezolid binding and cross-resistance.

Authors: Katherine S Long; Christian Munck; Theis M B Andersen; Maria A Schaub; Sven N Hobbie; Erik C Böttger; Birte Vester
Journal: Antimicrob Agents Chemother Date: 2010-08-09 Impact factor: 5.191

Review 5. Evolving resistance among Gram-positive pathogens.

Authors: Jose M Munita; Arnold S Bayer; Cesar A Arias
Journal: Clin Infect Dis Date: 2015-09-15 Impact factor: 9.079

6. Molecular detection of linezolid resistance in Enterococcus faecium and Enterococcus faecalis by use of 5' nuclease real-time PCR compared to a modified classical approach.

Authors: Guido Werner; Birgit Strommenger; Ingo Klare; Wolfgang Witte
Journal: J Clin Microbiol Date: 2004-11 Impact factor: 5.948

7. Heterogeneous macrolide resistance and gene conversion in the pneumococcus.

Authors: Nicole Wolter; Anthony M Smith; David J Farrell; Keith P Klugman
Journal: Antimicrob Agents Chemother Date: 2006-01 Impact factor: 5.191

8. Novel mechanism of resistance to oxazolidinones, macrolides, and chloramphenicol in ribosomal protein L4 of the pneumococcus.

Authors: Nicole Wolter; Anthony M Smith; David J Farrell; William Schaffner; Matthew Moore; Cynthia G Whitney; James H Jorgensen; Keith P Klugman
Journal: Antimicrob Agents Chemother Date: 2005-08 Impact factor: 5.191

9. Nosocomial spread of Enterococcus faecium resistant to vancomycin and linezolid in a tertiary care medical center.

Authors: Thomas E Dobbs; Mukesh Patel; Ken B Waites; Stephen A Moser; Alan M Stamm; Craig J Hoesley
Journal: J Clin Microbiol Date: 2006-09 Impact factor: 5.948

10. Tedizolid susceptibility in linezolid- and vancomycin-resistant Enterococcus faecium isolates.

Authors: E-M Klupp; A Both; C Belmar Campos; H Büttner; C König; M Christopeit; M Christner; M Aepfelbacher; H Rohde
Journal: Eur J Clin Microbiol Infect Dis Date: 2016-08-15 Impact factor: 3.267