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Literature DB >> 11476839

Linezolid resistance in a clinical isolate of Staphylococcus aureus.

S Tsiodras, H S Gold, G Sakoulas, G M Eliopoulos, C Wennersten, L Venkataraman, R C Moellering, M J Ferraro.

Abstract

The new oxazolidinone antimicrobial, linezolid, has been approved for the treatment of infections caused by various gram-positive bacteria, including meticillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant enterococci (VRE). Although instances of linezolid resistance in VRE have been reported, resistance has not been encountered among clinical isolates of S aureus. We have characterised an MRSA isolate resistant to linezolid that was recovered from a patient treated with this agent for dialysis-associated peritonitis.

Entities: Chemical Disease Species

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Year: 2001 PMID： 11476839 DOI： 10.1016/S0140-6736(01)05410-1

Source DB: PubMed Journal: Lancet ISSN： 0140-6736 Impact factor: 79.321

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Cited

206 in total

1. Effect of linezolid in comparison with that of vancomycin on glycocalix production: in vitro study.

Authors: L Drago; E De Vecchi; M Valli; L Nicola; M R Gismondo
Journal: Antimicrob Agents Chemother Date: 2002-02 Impact factor: 5.191

2. Detection of oxazolidinone-resistant Enterococcus faecalis and Enterococcus faecium strains by real-time PCR and PCR-restriction fragment length polymorphism analysis.

Authors: Neil Woodford; Luke Tysall; Cressida Auckland; Mark W Stockdale; Andrew J Lawson; Rachel A Walker; David M Livermore
Journal: J Clin Microbiol Date: 2002-11 Impact factor: 5.948

3. Rapid detection and estimation by pyrosequencing of 23S rRNA genes with a single nucleotide polymorphism conferring linezolid resistance in Enterococci.

Authors: Alistair Sinclair; Catherine Arnold; Neil Woodford
Journal: Antimicrob Agents Chemother Date: 2003-11 Impact factor: 5.191

4. Comparative activities of the oxazolidinone AZD2563 and linezolid against selected recent North American isolates of Streptococcus pneumoniae.

Authors: Sue E Baum; Sharon A Crawford; M L McElmeel; Cynthia G Whitney; James H Jorgensen
Journal: Antimicrob Agents Chemother Date: 2002-09 Impact factor: 5.191

10. Identification and characterization of the multidrug resistance gene cfr in a Panton-Valentine leukocidin-positive sequence type 8 methicillin-resistant Staphylococcus aureus IVa (USA300) isolate.

Authors: Anna C Shore; Orla M Brennan; Ralf Ehricht; Stefan Monecke; Stefan Schwarz; Peter Slickers; David C Coleman
Journal: Antimicrob Agents Chemother Date: 2010-10-04 Impact factor: 5.191

Linezolid resistance in a clinical isolate of Staphylococcus aureus.

1. Effect of linezolid in comparison with that of vancomycin on glycocalix production: in vitro study.

2. Detection of oxazolidinone-resistant Enterococcus faecalis and Enterococcus faecium strains by real-time PCR and PCR-restriction fragment length polymorphism analysis.

3. Rapid detection and estimation by pyrosequencing of 23S rRNA genes with a single nucleotide polymorphism conferring linezolid resistance in Enterococci.

4. Comparative activities of the oxazolidinone AZD2563 and linezolid against selected recent North American isolates of Streptococcus pneumoniae.

Review 5. Antimicrobial resistance: the example of Staphylococcus aureus.

6. Linezolid in VAP by MRSA: a better choice?

7. Gene dosage and linezolid resistance in Enterococcus faecium and Enterococcus faecalis.

8. Single-dose pharmacokinetics and safety of a novel broad-spectrum cephalosporin (BAL5788) in healthy volunteers.

9. In vitro and in vivo activities of LCB01-0371, a new oxazolidinone.

10. Identification and characterization of the multidrug resistance gene cfr in a Panton-Valentine leukocidin-positive sequence type 8 methicillin-resistant Staphylococcus aureus IVa (USA300) isolate.