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Literature DB >> 12234856

-11 Mutation in the ampC promoter increasing resistance to beta-lactams in a clinical Escherichia coli strain.

S Corvec¹, N Caroff, E Espaze, J Marraillac, A Reynaud.

Abstract

A mutation was discovered in the Pribnow box of the ampC promoter in a clinical Escherichia coli strain. This -11 C-to-T transition created a perfect homology with the -10 consensus sequence. The new promoter was cloned upstream of the cat gene of pKK232-8 and induced a sixfold increase in promoter strength.

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Year: 2002 PMID： 12234856 PMCID： PMC128767 DOI： 10.1128/AAC.46.10.3265-3267.2002

Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN： 0066-4804 Impact factor: 5.191

12 in total

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3. Molecular diversity and evolution of blaTEM genes encoding beta-lactamases resistant to clavulanic acid in clinical E. coli.

Authors: M M Caniça; C Y Lu; R Krishnamoorthy; G C Paul
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5. Protected environments allow parallel evolution of a bacterial pathogen in a patient subjected to long-term antibiotic therapy.

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6. Molecular and genetic aspects of the fumarate reductase of Escherichia coli.

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Review 7. Compilation and analysis of Escherichia coli promoter DNA sequences.

Authors: D K Hawley; W R McClure
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8. ampC cephalosporinase of Escherichia coli K-12 has a different evolutionary origin from that of beta-lactamases of the penicillinase type.

Authors: B Jaurin; T Grundström
Journal: Proc Natl Acad Sci U S A Date: 1981-08 Impact factor: 11.205

9. Molecular basis of AmpC hyperproduction in clinical isolates of Escherichia coli.

Authors: E C Nelson; B G Elisha
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10. Sequence elements determining ampC promoter strength in E. coli.

Authors: B Jaurin; T Grundström; S Normark
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