Literature DB >> 12185678

Synthesis of adenine from HCN tetramer and ammonium formate.

Aubrey Hill1, Leslie E Orgel.   

Abstract

Adenine is formed in about 18% yield when HCN tetramer is heated with ammonium formate at 110 degrees C. The prebiotic significance of this reaction is discussed.

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Year:  2002        PMID： 12185678     DOI： 10.1023/a:1016070723772

Source DB:  PubMed          Journal:  Orig Life Evol Biosph        ISSN： 0169-6149            Impact factor:   1.950


  5 in total

1.  Prebiotic synthesis of nucleotides.

Authors:  G Zubay; T Mui
Journal:  Orig Life Evol Biosph       Date:  2001 Feb-Apr       Impact factor: 1.950

2.  Mechanism of synthesis of adenine from hydrogen cyanide under possible primitive earth conditions.

Authors:  J ORO
Journal:  Nature       Date:  1961-09-16       Impact factor: 49.962

3.  RNA evolution and the origins of life.

Authors:  G F Joyce
Journal:  Nature       Date:  1989-03-16       Impact factor: 49.962

4.  Studies in prebiotic synthesis. II. Synthesis of purine precursors and amino acids from aqueous hydrogen cyanide.

Authors:  R A Sanchez; J P Ferris; L E Orgel
Journal:  J Mol Biol       Date:  1967-12-14       Impact factor: 5.469

5.  A possible prebiotic synthesis of purine, adenine, cytosine, and 4(3H)-pyrimidinone from formamide: implications for the origin of life.

Authors:  R Saladino; C Crestini; G Costanzo; R Negri; E Di Mauro
Journal:  Bioorg Med Chem       Date:  2001-05       Impact factor: 3.641
  5 in total
  8 in total

Review 1.  Closing the circle: replicating RNA with RNA.

Authors:  Leslie K L Cheng; Peter J Unrau
Journal:  Cold Spring Harb Perspect Biol       Date:  2010-06-16       Impact factor: 10.005

2.  The effects of borate minerals on the synthesis of nucleic acid bases, amino acids and biogenic carboxylic acids from formamide.

Authors:  Raffaele Saladino; Maurizio Barontini; Cristina Cossetti; Ernesto Di Mauro; Claudia Crestini
Journal:  Orig Life Evol Biosph       Date:  2011-03-19       Impact factor: 1.950

3.  The Dissipative Photochemical Origin of Life: UVC Abiogenesis of Adenine.

Authors:  Karo Michaelian
Journal:  Entropy (Basel)       Date:  2021-02-10       Impact factor: 2.524

4.  An investigation of prebiotic purine synthesis from the hydrolysis of HCN polymers.

Authors:  Eduardo Borquez; H James Cleaves; Antonio Lazcano; Stanley L Miller
Journal:  Orig Life Evol Biosph       Date:  2005-04       Impact factor: 1.950

5.  Thermodynamic potential for the abiotic synthesis of adenine, cytosine, guanine, thymine, uracil, ribose, and deoxyribose in hydrothermal systems.

Authors:  Douglas E LaRowe; Pierre Regnier
Journal:  Orig Life Evol Biosph       Date:  2008-06-24       Impact factor: 1.950

6.  Adenine Synthesis in a Model Prebiotic Reaction: Connecting Origin of Life Chemistry with Biology.

Authors:  Lakshmi N Anumukonda; Avery Young; David G Lynn; Ragan Buckley; Amena Warrayat; Christina L Graves; Heather D Bean; Nicholas V Hud
Journal:  J Chem Educ       Date:  2011-10-17       Impact factor: 2.979

7.  Dissipative Photochemical Abiogenesis of the Purines.

Authors:  Claudeth Hernández; Karo Michaelian
Journal:  Entropy (Basel)       Date:  2022-07-26       Impact factor: 2.738

Review 8.  Illuminating Life's Origins: UV Photochemistry in Abiotic Synthesis of Biomolecules.

Authors:  Nicholas J Green; Jianfeng Xu; John D Sutherland
Journal:  J Am Chem Soc       Date:  2021-04-21       Impact factor: 15.419
  8 in total

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