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Literature DB >> 2466202

RNA evolution and the origins of life.

Abstract

The evolution of RNA is likely to have played an important role in the very early history of life on Earth but it is doubtful that life began with RNA. Consideration of what came before RNA must take into account relevant information from geochemistry, prebiotic chemistry and nucleic acid biochemistry.

Mesh：

Substances：
Carbohydrates
Purines
RNA

Year: 1989 PMID： 2466202 DOI： 10.1038/338217a0

Source DB: PubMed Journal: Nature ISSN： 0028-0836 Impact factor: 49.962

Keyword Cloud
Cited

151 in total

1. Prebiotic synthesis of nucleotides.

Authors: G Zubay; T Mui
Journal: Orig Life Evol Biosph Date: 2001 Feb-Apr Impact factor: 1.950

2. Use of DNA, RNA, and chimeric templates by a viral RNA-dependent RNA polymerase: evolutionary implications for the transition from the RNA to the DNA world.

Authors: R W Siegel; L Bellon; L Beigelman; C C Kao
Journal: J Virol Date: 1999-08 Impact factor: 5.103

3. The fidelity of template-directed oligonucleotide ligation and the inevitability of polymerase function.

Authors: K D James; A D Ellington
Journal: Orig Life Evol Biosph Date: 1999-08 Impact factor: 1.950

4. The possible role of volcanic aquifers in prebiologic genesis of organic compounds and RNA.

Authors: J Washington
Journal: Orig Life Evol Biosph Date: 2000-02 Impact factor: 1.950

5. Two-dimensional life?

Authors: C de Duve; S L Miller
Journal: Proc Natl Acad Sci U S A Date: 1991-11 Impact factor: 11.205

6. Speculations on the origin of life and thermophily: review of available information on reverse gyrase suggests that hyperthermophilic procaryotes are not so primitive.

Authors: P Forterre; F Confalonieri; F Charbonnier; M Duguet
Journal: Orig Life Evol Biosph Date: 1995-06 Impact factor: 1.950

RNA evolution and the origins of life.

1. Prebiotic synthesis of nucleotides.

2. Use of DNA, RNA, and chimeric templates by a viral RNA-dependent RNA polymerase: evolutionary implications for the transition from the RNA to the DNA world.

3. The fidelity of template-directed oligonucleotide ligation and the inevitability of polymerase function.

4. The possible role of volcanic aquifers in prebiologic genesis of organic compounds and RNA.

5. Two-dimensional life?

6. Speculations on the origin of life and thermophily: review of available information on reverse gyrase suggests that hyperthermophilic procaryotes are not so primitive.

7. Binding of adenine and adenine-related compounds to the clay montmorillonite and the mineral hydroxylapatite.

8. The role of accuracy for early stages of the origin of life.

9. Importance of compartment formation for a self-encoding system.

10. A system of two polymerases--a model for the origin of life.