Literature DB >> 12163617

Genetically stable picornavirus expression vectors with recombinant internal ribosomal entry sites.

Andrew T Dufresne1, Elena Y Dobrikova, Stacie Schmidt, Matthias Gromeier.   

Abstract

In many respects, picornaviruses are well suited for their proposed use as immunization vectors. However, their inherent genetic instability hinders application for prophylactic purposes. We demonstrate the improved expression and stability of a heterologous insert through a novel vector design strategy that partially replaces noncoding regulatory sequences with coding sequences for foreign gene products.

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Year:  2002        PMID： 12163617      PMCID： PMC136971          DOI： 10.1128/jvi.76.17.8966-8972.2002

Source DB:  PubMed          Journal:  J Virol        ISSN： 0022-538X            Impact factor:   5.103


  26 in total

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Authors:  M J Schnell
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Authors:  J Pelletier; N Sonenberg
Journal:  J Virol       Date:  1989-01       Impact factor: 5.103

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Authors:  S Kuge; A Nomoto
Journal:  J Virol       Date:  1987-05       Impact factor: 5.103

4.  A segment of the 5' nontranslated region of encephalomyocarditis virus RNA directs internal entry of ribosomes during in vitro translation.

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Journal:  J Virol       Date:  1988-08       Impact factor: 5.103

5.  Primary structure, gene organization and polypeptide expression of poliovirus RNA.

Authors:  N Kitamura; B L Semler; P G Rothberg; G R Larsen; C J Adler; A J Dorner; E A Emini; R Hanecak; J J Lee; S van der Werf; C W Anderson; E Wimmer
Journal:  Nature       Date:  1981-06-18       Impact factor: 49.962

6.  The 5' end of poliovirus mRNA is not capped with m7G(5')ppp(5')Np.

Authors:  A Nomoto; Y F Lee; E Wimmer
Journal:  Proc Natl Acad Sci U S A       Date:  1976-02       Impact factor: 11.205

7.  Intergeneric poliovirus recombinants for the treatment of malignant glioma.

Authors:  M Gromeier; S Lachmann; M R Rosenfeld; P H Gutin; E Wimmer
Journal:  Proc Natl Acad Sci U S A       Date:  2000-06-06       Impact factor: 11.205

8.  Initiation of protein synthesis by internal entry of ribosomes into the 5' nontranslated region of encephalomyocarditis virus RNA in vivo.

Authors:  S K Jang; M V Davies; R J Kaufman; E Wimmer
Journal:  J Virol       Date:  1989-04       Impact factor: 5.103

9.  Mucosal immunization of cynomolgus macaques with two serotypes of live poliovirus vectors expressing simian immunodeficiency virus antigens: stimulation of humoral, mucosal, and cellular immunity.

Authors:  S Crotty; B L Lohman; F X Lü; S Tang; C J Miller; R Andino
Journal:  J Virol       Date:  1999-11       Impact factor: 5.103

10.  Internal initiation of translation of eukaryotic mRNA directed by a sequence derived from poliovirus RNA.

Authors:  J Pelletier; N Sonenberg
Journal:  Nature       Date:  1988-07-28       Impact factor: 49.962
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  7 in total

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Authors:  Melinda K Merrill; Guenter Bernhardt; John H Sampson; Carol J Wikstrand; Darell D Bigner; Matthias Gromeier
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Authors:  Kevin D Pavelko; Michael P Bell; Lavakumar Karyampudi; Michael J Hansen; Kathleen S Allen; Keith L Knutson; Larry R Pease
Journal:  Mol Ther       Date:  2013-04-09       Impact factor: 11.454

Review 4.  Therapeutic Use of Native and Recombinant Enteroviruses.

Authors:  Jani Ylä-Pelto; Lav Tripathi; Petri Susi
Journal:  Viruses       Date:  2016-02-23       Impact factor: 5.048

5.  Packaging of porcine reproductive and respiratory syndrome virus replicon RNA by a stable cell line expressing its nucleocapsid protein.

Authors:  Byung-Hak Song; Jeong-Min Kim; Jin-Kyoung Kim; Han-Saem Jang; Gil-Nam Yun; Eun-Jin Choi; Jae-Young Song; Sang-Im Yun; Young-Min Lee
Journal:  J Microbiol       Date:  2011-06-30       Impact factor: 3.422

6.  Genetically stable poliovirus vectors activate dendritic cells and prime antitumor CD8 T cell immunity.

Authors:  Mubeen M Mosaheb; Elena Y Dobrikova; Michael C Brown; Yuanfan Yang; Jana Cable; Hideho Okada; Smita K Nair; Darell D Bigner; David M Ashley; Matthias Gromeier
Journal:  Nat Commun       Date:  2020-01-27       Impact factor: 14.919

7.  Kunjin replicon-based simian immunodeficiency virus gag vaccines.

Authors:  Itaru Anraku; Vladislav V Mokhonov; Paweena Rattanasena; Ekaterina I Mokhonova; Jason Leung; Gorben Pijlman; Andrea Cara; Wayne A Schroder; Alexander A Khromykh; Andreas Suhrbier
Journal:  Vaccine       Date:  2008-04-21       Impact factor: 3.641
  7 in total

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