Literature DB >> 12086692

Absorption and urinary excretion of procyanidin B2 [epicatechin-(4beta-8)-epicatechin] in rats.

Seigo Baba1, Naomi Osakabe, Midori Natsume, Junji Terao.   

Abstract

We evaluated the bioavailability and plasma antioxidative activity after administration of procyanidin B2 [epicatechin-(4beta-8)-epicatechin] in rats. After procyanidin B2 administration, procyanidin B2 is absorbed and excreted in urine, and a portion of the PB2 is degraded to (-)-epicatechin and to the metabolized conjugated and/or methylated (-)-epicatechin internally in the rat. Moreover, PB2 reduces the accumulation of lipid peroxide in plasma oxidized by copper ions.

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Year:  2002        PMID： 12086692     DOI： 10.1016/s0891-5849(02)00871-7

Source DB:  PubMed          Journal:  Free Radic Biol Med        ISSN： 0891-5849            Impact factor:   7.376


  30 in total

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4.  Distribution of procyanidins and their metabolites in rat plasma and tissues in relation to ingestion of procyanidin-enriched or procyanidin-rich cocoa creams.

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7.  Cacao polyphenols ameliorate autoimmune myocarditis in mice.

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Review 8.  Cocoa, chocolate, and cardiovascular disease.

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Journal:  J Cardiovasc Pharmacol       Date:  2009-12       Impact factor: 3.105

9.  Liquid chromatography tandem mass spectrometry identification of proanthocyanidins in rat plasma after oral administration of grape seed extract.

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Journal:  Phytomedicine       Date:  2008-12-17       Impact factor: 5.340

10.  Dose-dependent hypocholesterolemic actions of dietary apple polyphenol in rats fed cholesterol.

Authors:  Kyoichi Osada; Takashi Suzuki; Yuki Kawakami; Mineo Senda; Atsushi Kasai; Manabu Sami; Yutaka Ohta; Tomomasa Kanda; Mitsuo Ikeda
Journal:  Lipids       Date:  2006-02       Impact factor: 1.880
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