Literature DB >> 1194311

An unusual reaction in muscle in association with Vitallium plate: a report of possible metal hypersensitivity.

D S Halpin.   

Abstract

A case is reported in which fractures of the radius and ulna were fixed with Vitallium plates and screws. Seven years later a painful swelling appeared over the extensor aspect of the forearm. After eight years sarcoma was suspected and a pale tumour infiltrating muscle was found at operation. However, the histology excluded neoplasia and showed massive fibrosis and patchy necrosis of muscle, with chronic inflammatory changes peripherally. After the removal of the metal the swelling disappeared. A sinus down to the ulna followed operation and was not cured two years later. At this stage standard patch testing showed skin sensitivity to cobalt. Metal sensitivity is proposed as the cause of this extraordinary reaction in muscle.

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Year:  1975        PMID: 1194311

Source DB:  PubMed          Journal:  J Bone Joint Surg Br        ISSN: 0301-620X


  11 in total

1.  In vitro reactivity to implant metals demonstrates a person-dependent association with both T-cell and B-cell activation.

Authors:  Nadim James Hallab; Marco Caicedo; Rachel Epstein; Kyron McAllister; Joshua J Jacobs
Journal:  J Biomed Mater Res A       Date:  2010-02       Impact factor: 4.396

Review 2.  Nickel-free austenitic stainless steels for medical applications.

Authors:  Ke Yang; Yibin Ren
Journal:  Sci Technol Adv Mater       Date:  2010-02-26       Impact factor: 8.090

3.  [Metallurgical differentiation of cobalt-chromium alloys for implants].

Authors:  U Holzwarth; P Thomas; W Kachler; J Göske; A Schuh
Journal:  Orthopade       Date:  2005-10       Impact factor: 1.087

4.  Metal allergy: a false alarm?

Authors: 
Journal:  Br Med J       Date:  1980-11-15

5.  [Pathological findings in tissue surrounding revised metal/metal articulations].

Authors:  W Baur; W Hönle; H-G Willert; A Schuh
Journal:  Orthopade       Date:  2005-03       Impact factor: 1.087

6.  Orthopaedic implant related metal toxicity in terms of human lymphocyte reactivity to metal-protein complexes produced from cobalt-base and titanium-base implant alloy degradation.

Authors:  N J Hallab; K Mikecz; C Vermes; A Skipor; J J Jacobs
Journal:  Mol Cell Biochem       Date:  2001-06       Impact factor: 3.396

7.  The imaging spectrum of peri-articular inflammatory masses following metal-on-metal hip resurfacing.

Authors:  Christopher S J Fang; Paul Harvie; Christopher L M H Gibbons; Duncan Whitwell; Nicholas A Athanasou; Simon Ostlere
Journal:  Skeletal Radiol       Date:  2008-05-14       Impact factor: 2.199

Review 8.  Corrosion degradation and prevention by surface modification of biometallic materials.

Authors:  Raghuvir Singh; Narendra B Dahotre
Journal:  J Mater Sci Mater Med       Date:  2006-12-02       Impact factor: 4.727

9.  A review of the biologic effects of spine implant debris: Fact from fiction.

Authors:  Nadim James Hallab
Journal:  SAS J       Date:  2009-12-01

Review 10.  Metal Hypersensitivity Reactions to Orthopedic Implants.

Authors:  Wendy Z W Teo; Peter C Schalock
Journal:  Dermatol Ther (Heidelb)       Date:  2016-12-19
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