Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Histone modifications in transcriptional regulation.

Literature DB >> 11893486

Histone modifications in transcriptional regulation.

Abstract

Covalent modifications of the amino termini of the core histones in nucleosomes have important roles in gene regulation. Research in the past two years reveals these modifications to consist of phosphorylation, methylation and ubiquitination, in addition to the better-characterized acetylation. This multiplicity of modifications, and their occurrence in patterns and dependent sequences, argues persuasively for the existence of a histone code.

Mesh：

Substances：

Year: 2002 PMID： 11893486 DOI： 10.1016/s0959-437x(02)00279-4

Source DB: PubMed Journal: Curr Opin Genet Dev ISSN： 0959-437X Impact factor: 5.578

Keyword Cloud
Cited

421 in total

1. The CBP bromodomain and nucleosome targeting are required for Zta-directed nucleosome acetylation and transcription activation.

Authors: Zhong Deng; Chi-Ju Chen; Michaela Chamberlin; Fang Lu; Gerd A Blobel; David Speicher; Lisa Ann Cirillo; Kenneth S Zaret; Paul M Lieberman
Journal: Mol Cell Biol Date: 2003-04 Impact factor: 4.272

2. Identification of a functional domain within the essential core of histone H3 that is required for telomeric and HM silencing in Saccharomyces cerevisiae.

Authors: Jeffrey S Thompson; Marilyn L Snow; Summer Giles; Leslie E McPherson; Michael Grunstein
Journal: Genetics Date: 2003-01 Impact factor: 4.562

10. Monocytic leukemia zinc finger protein is essential for the development of long-term reconstituting hematopoietic stem cells.

Authors: Tim Thomas; Lynn M Corcoran; Raffi Gugasyan; Mathew P Dixon; Thomas Brodnicki; Stephen L Nutt; Donald Metcalf; Anne K Voss
Journal: Genes Dev Date: 2006-05-01 Impact factor: 11.361

Histone modifications in transcriptional regulation.

1. The CBP bromodomain and nucleosome targeting are required for Zta-directed nucleosome acetylation and transcription activation.

2. Identification of a functional domain within the essential core of histone H3 that is required for telomeric and HM silencing in Saccharomyces cerevisiae.

3. Cascade of distinct histone modifications during collagenase gene activation.

4. SWI/SNF-dependent chromatin remodeling of RNR3 requires TAF(II)s and the general transcription machinery.

Review 5. Histone modifications and alcohol-induced liver disease: are altered nutrients the missing link?

6. Chaperone-mediated acetylation of histones by Rtt109 identified by quantitative proteomics.

Review 7. Role of chromatin states in transcriptional memory.

8. HISTONE DEACETYLASE19 is involved in jasmonic acid and ethylene signaling of pathogen response in Arabidopsis.

9. Epigenetic and genetic mechanisms contribute to telomerase inhibition by EGCG.

10. Monocytic leukemia zinc finger protein is essential for the development of long-term reconstituting hematopoietic stem cells.