Literature DB >> 11867802

Morphologic phenotyping with MR microscopy: the visible mouse.

G Allan Johnson1, Gary P Cofer, Sally L Gewalt, Laurence W Hedlund.   

Abstract

A method for rapid morphologic phenotyping is demonstrated by using magnetic resonance microscopy. Whole fixed C57BL/6J mice were imaged at 110-microm isotropic resolution; limited volumes of the intact specimen, at 50-microm isotropic resolution; and isolated organs, at 25-microm isotropic resolution. The three-dimensional imaging technique was applied to uricase knockout mice to demonstrate the method for the evaluation of morphologic phenotype.

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Year:  2002        PMID： 11867802     DOI： 10.1148/radiol.2223010531

Source DB:  PubMed          Journal:  Radiology        ISSN： 0033-8419            Impact factor:   11.105


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