Literature DB >> 11847291

Evaluation of the energetic contribution of an ionic network to beta-sheet stability.

Kirsten S Lassila1, Deepshikha Datta, Stephen L Mayo.   

Abstract

We have evaluated the interaction energy of a three-residue ionic network constructed on the beta-sheet surface of protein G using double mutant cycles. Although the two individual ion pairs were each stabilizing by 0.6 kcal/mol, the excess gain in stability for the triad was small (0.06 kcal/mol).

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Year:  2002        PMID： 11847291      PMCID： PMC2373463          DOI： 10.1110/ps.23502

Source DB:  PubMed          Journal:  Protein Sci        ISSN： 0961-8368            Impact factor:   6.725


  19 in total

1.  Intrinsic beta-sheet propensities result from van der Waals interactions between side chains and the local backbone.

Authors:  A G Street; S L Mayo
Journal:  Proc Natl Acad Sci U S A       Date:  1999-08-03       Impact factor: 11.205

2.  Contribution of salt bridges near the surface of a protein to the conformational stability.

Authors:  K Takano; K Tsuchimori; Y Yamagata; K Yutani
Journal:  Biochemistry       Date:  2000-10-10       Impact factor: 3.162

3.  Trading accuracy for speed: A quantitative comparison of search algorithms in protein sequence design.

Authors:  C A Voigt; D B Gordon; S L Mayo
Journal:  J Mol Biol       Date:  2000-06-09       Impact factor: 5.469

4.  Estimating the contribution of engineered surface electrostatic interactions to protein stability by using double-mutant cycles.

Authors:  L Serrano; A Horovitz; B Avron; M Bycroft; A R Fersht
Journal:  Biochemistry       Date:  1990-10-09       Impact factor: 3.162

5.  Thermodynamic analysis of the folding of the streptococcal protein G IgG-binding domains B1 and B2: why small proteins tend to have high denaturation temperatures.

Authors:  P Alexander; S Fahnestock; T Lee; J Orban; P Bryan
Journal:  Biochemistry       Date:  1992-04-14       Impact factor: 3.162

6.  Strength and co-operativity of contributions of surface salt bridges to protein stability.

Authors:  A Horovitz; L Serrano; B Avron; M Bycroft; A R Fersht
Journal:  J Mol Biol       Date:  1990-12-20       Impact factor: 5.469

7.  Strategy for analysing the co-operativity of intramolecular interactions in peptides and proteins.

Authors:  A Horovitz; A R Fersht
Journal:  J Mol Biol       Date:  1990-08-05       Impact factor: 5.469

8.  Sidechain interactions in parallel beta sheets: the energetics of cross-strand pairings.

Authors:  J S Merkel; J M Sturtevant; L Regan
Journal:  Structure       Date:  1999-11-15       Impact factor: 5.006

9.  Contributions of engineered surface salt bridges to the stability of T4 lysozyme determined by directed mutagenesis.

Authors:  D P Sun; U Sauer; H Nicholson; B W Matthews
Journal:  Biochemistry       Date:  1991-07-23       Impact factor: 3.162

10.  Energetic contribution of solvent-exposed ion pairs to alpha-helix structure.

Authors:  P C Lyu; P J Gans; N R Kallenbach
Journal:  J Mol Biol       Date:  1992-01-05       Impact factor: 5.469
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  4 in total

1.  Boosting protein stability with the computational design of β-sheet surfaces.

Authors:  Doo Nam Kim; Timothy M Jacobs; Brian Kuhlman
Journal:  Protein Sci       Date:  2016-01-13       Impact factor: 6.725

2.  Stabilizing salt-bridge enhances protein thermostability by reducing the heat capacity change of unfolding.

Authors:  Chi-Ho Chan; Tsz-Ha Yu; Kam-Bo Wong
Journal:  PLoS One       Date:  2011-06-24       Impact factor: 3.240

Review 3.  Physicochemical Properties of Ion Pairs of Biological Macromolecules.

Authors:  Junji Iwahara; Alexandre Esadze; Levani Zandarashvili
Journal:  Biomolecules       Date:  2015-09-30

4.  Establishing knowledge on the sequence arrangement pattern of nucleated protein folding.

Authors:  Fei Leng; Chao Xu; Xia-Yu Xia; Xian-Ming Pan
Journal:  PLoS One       Date:  2017-03-08       Impact factor: 3.240
  4 in total

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