Literature DB >> 2388258

Strategy for analysing the co-operativity of intramolecular interactions in peptides and proteins.

A Horovitz1, A R Fersht.   

Abstract

Double mutant cycles enable the measurement of pairwise interactions in proteins. This method is extended for mutations at any number of positions in the protein. This provides a way for determining the context dependence of pairwise interactions on other neighbouring residues.

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Year:  1990        PMID： 2388258     DOI： 10.1016/0022-2836(90)90275-Q

Source DB:  PubMed          Journal:  J Mol Biol        ISSN： 0022-2836            Impact factor:   5.469


  131 in total

1.  Aromatics at the murine nicotinic receptor agonist binding site: mutational analysis of the alphaY93 and alphaW149 residues.

Authors:  G Akk
Journal:  J Physiol       Date:  2001-09-15       Impact factor: 5.182

2.  Unspecific hydrophobic stabilization of folding transition states.

Authors:  Ana Rosa Viguera; Cristina Vega; Luis Serrano
Journal:  Proc Natl Acad Sci U S A       Date:  2002-04-16       Impact factor: 11.205

3.  Subunit-selective contribution to channel gating of the M4 domain of the nicotinic receptor.

Authors:  Cecilia Bouzat; Fernanda Gumilar; María del Carmen Esandi; Steven M Sine
Journal:  Biophys J       Date:  2002-04       Impact factor: 4.033

4.  Propagation of a single destabilizing mutation throughout the Escherichia coli ribonuclease HI native state.

Authors:  Giulietta Spudich; Sonja Lorenz; Susan Marqusee
Journal:  Protein Sci       Date:  2002-03       Impact factor: 6.725

5.  Evaluation of the energetic contribution of an ionic network to beta-sheet stability.

Authors:  Kirsten S Lassila; Deepshikha Datta; Stephen L Mayo
Journal:  Protein Sci       Date:  2002-03       Impact factor: 6.725

6.  Structure of the interferon-receptor complex determined by distance constraints from double-mutant cycles and flexible docking.

Authors:  L C Roisman; J Piehler; J Y Trosset; H A Scheraga; G Schreiber
Journal:  Proc Natl Acad Sci U S A       Date:  2001-11-06       Impact factor: 11.205

7.  A general method for the quantitative analysis of functional chimeras: applications from site-directed mutagenesis and macromolecular association.

Authors:  T N Luong; J F Kirsch
Journal:  Protein Sci       Date:  2001-03       Impact factor: 6.725

8.  Contributions of the non-alpha subunit residues (loop D) to agonist binding and channel gating in the muscle nicotinic acetylcholine receptor.

Authors:  Gustav Akk
Journal:  J Physiol       Date:  2002-11-01       Impact factor: 5.182

Review 9.  Biological phosphoryl-transfer reactions: understanding mechanism and catalysis.

Authors:  Jonathan K Lassila; Jesse G Zalatan; Daniel Herschlag
Journal:  Annu Rev Biochem       Date:  2011       Impact factor: 23.643

10.  Interaction of the aromatics Tyr-72/Trp-288 in the interface of the extracellular and transmembrane domains is essential for proton gating of acid-sensing ion channels.

Authors:  Tianbo Li; Youshan Yang; Cecilia M Canessa
Journal:  J Biol Chem       Date:  2008-12-11       Impact factor: 5.157
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