Literature DB >> 1180577

Glycerol: major contributor to the short term protein sparing effect of fat emulsions in normal man.

M F Brennan, G F Fitzpatrick, K H Cohen, F D Moore.   

Abstract

Intravenous fat emulsions have been advocated as acceptable alternatives to hyperosmolar glucose solutions in parenteral nutrition. The ability of a fat emulsion (soy bean oil suspended in glycerol) to produce nitrogen sparing in the absence of nitrogen intake was examined in normal man. The protein conservation obtained by the fat emulsion can be duplicated by the infusion of glycerol alone in the same amount as that available from the fat emulsion.

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Year:  1975        PMID: 1180577      PMCID: PMC1343997          DOI: 10.1097/00000658-197510000-00004

Source DB:  PubMed          Journal:  Ann Surg        ISSN: 0003-4932            Impact factor:   12.969


  31 in total

1.  ORAL GLYCEROL FOR THE REDUCTION OF INTRACRANIAL PRESSURE.

Authors:  G CANTORE; B GUIDETTI; M VIRNO
Journal:  J Neurosurg       Date:  1964-04       Impact factor: 5.115

2.  The relationship of carbohydrate metabolism to protein metabolism. IV. The effect of substituting fat for dietary carbohydrate.

Authors:  W S THOMSON; H N MUNRO
Journal:  J Nutr       Date:  1955-05-10       Impact factor: 4.798

3.  The proteinsparing effect of intravenous fat emulsion; a preliminary report.

Authors:  C P ARTZ; T K WILLIAMS
Journal:  Metabolism       Date:  1957-11       Impact factor: 8.694

4.  The influence of energy intake on protein metabolism.

Authors:  H N MUNRO; D J NAISMITH
Journal:  Biochem J       Date:  1953-05       Impact factor: 3.857

5.  The Influence of Fat and Carbohydrate on the Nitrogen Distribution in the Urine.

Authors:  E P Cathcart
Journal:  Biochem J       Date:  1922       Impact factor: 3.857

6.  The influence of carbohydrates and fats on protein metabolism.

Authors:  E P Cathcart
Journal:  J Physiol       Date:  1909-10-22       Impact factor: 5.182

7.  Will fat emulsions given intravenously promote protein synthesis? Metabolic studies on normal subjects and surgical patients.

Authors:  T B VAN ITALLIE; F D MOORE; R P GEYER; F J STARE
Journal:  Surgery       Date:  1954-10       Impact factor: 3.982

8.  Carbohydrate and fat as factors in protein utilization and metabolism.

Authors:  H N MUNRO
Journal:  Physiol Rev       Date:  1951-10       Impact factor: 37.312

9.  Treatment with glycerol of cerebral oedema due to acute cerebral infarction.

Authors:  J S Meyer; J Z Charney; V M Rivera; N T Mathew
Journal:  Lancet       Date:  1971-11       Impact factor: 79.321

10.  Hormone-fuel interrelationships during fasting.

Authors:  G F Cahill; M G Herrera; A P Morgan; J S Soeldner; J Steinke; P L Levy; G A Reichard; D M Kipnis
Journal:  J Clin Invest       Date:  1966-11       Impact factor: 14.808

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  12 in total

1.  Metabolic studies of a lipid emulsion containing medium-chain triglyceride in perioperative and total parenteral nutrition infusions.

Authors:  R F Dawes; G T Royle; A R Dennison; P J Crowe; M Ball
Journal:  World J Surg       Date:  1986-02       Impact factor: 3.352

2.  Evidence for a role of free fatty acids in the regulation of somatostatin secretion in normal and alloxan diabetic dogs.

Authors:  T Wasada; B Howard; R E Dobbs; R H Unger
Journal:  J Clin Invest       Date:  1980-09       Impact factor: 14.808

3.  Glucose-lipid ratio is a determinant of nitrogen balance during total parenteral nutrition in critically ill patients: a prospective, randomized, multicenter blind trial with an intention-to-treat analysis.

Authors:  P Boulétreau; D Chassard; B Allaouchiche; J C Dumont; C Auboyer; M Bertin-Maghit; H Bricard; R Ecochard; J Rangaraj; C Chambrier; C Schneid; L Cynober
Journal:  Intensive Care Med       Date:  2005-08-24       Impact factor: 17.440

4.  Comparison of medium and long chain triglyceride metabolism in intensive care patients on parenteral nutrition.

Authors:  M J Ball; K White
Journal:  Intensive Care Med       Date:  1989       Impact factor: 17.440

5.  Multiomics assessment of dietary protein titration reveals altered hepatic glucose utilization.

Authors:  Michael R MacArthur; Sarah J Mitchell; Katia S Chadaideh; J Humberto Treviño-Villarreal; Jonathan Jung; Krystle C Kalafut; Justin S Reynolds; Charlotte G Mann; Kaspar M Trocha; Ming Tao; Tay-Zar Aye Cho; Anantawat Koontanatechanon; Vladimir Yeliseyev; Lynn Bry; Alban Longchamp; C Keith Ozaki; Caroline A Lewis; Rachel N Carmody; James R Mitchell
Journal:  Cell Rep       Date:  2022-08-16       Impact factor: 9.995

6.  Substrate interaction in intravenous feeding: comparative effects of carbohydrate and fat on amino acid utilization in fasting man.

Authors:  B M Wolfe; J M Culebras; A J Sim; M R Ball; F D Moore
Journal:  Ann Surg       Date:  1977-10       Impact factor: 12.969

7.  Intravenous amino acids as the sole nutritional substrate. Utilization and metabolism in fasting normal human subjects.

Authors:  D E Tweedle; G F Fitzpatrick; M F Brennan; J M Culebras; B M Wolfe; M R Ball; F D Moore
Journal:  Ann Surg       Date:  1977-07       Impact factor: 12.969

8.  Studies with a safflower oil emulsion in total parenteral nutrition.

Authors:  K H Wong; M Deitel
Journal:  Can Med Assoc J       Date:  1981-12-15       Impact factor: 8.262

9.  Influence of total parenteral nutrition on tissue lipoprotein lipase activity during chronic and acute illness.

Authors:  A P Robin; M R Greenwood; J Askanazi; D H Elwyn; J M Kinney
Journal:  Ann Surg       Date:  1981-12       Impact factor: 12.969

10.  Regulation of leucine catabolism by caloric sources. Role of glucose and lipid in nitrogen sparing during nitrogen deprivation.

Authors:  J A Vazquez; H S Paul; S A Adibi
Journal:  J Clin Invest       Date:  1988-11       Impact factor: 14.808

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