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Literature DB >> 11747699

Multidrug-resistant tuberculosis in prison inmates, Azerbaijan.

G E Pfyffer¹, A Strässle, T van Gorkum, F Portaels, L Rigouts, C Mathieu, F Mirzoyev, H Traore, J D van Embden.

Abstract

In a tuberculosis (TB) program in the Central Penitentiary Hospital of Azerbaijan, we analyzed 65 isolates of Mycobacterium tuberculosis by IS6110-based restriction fragment-length polymorphism (RFLP) and spoligotyping. From 11 clusters associated with 33 patients, 31 isolates had an IS6110-based banding pattern characteristic of the Beijing genotype of M. tuberculosis. In addition, 15 M. tuberculosis isolates with similar RFLP patterns constituted a single group by spoligotyping, matching the Beijing genotype. Multidrug resistance, always involving isoniazid and rifampin, was seen in 34 (52.3%) of 65 isolates, with 28 belonging to the Beijing genotype.

Entities: Chemical Disease Species

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Year: 2001 PMID： 11747699 PMCID： PMC2631864 DOI： 10.3201/eid0705.017514

Source DB: PubMed Journal: Emerg Infect Dis ISSN： 1080-6040 Impact factor: 6.883

28 in total

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