Literature DB >> 16585780

Identification of Nudix hydrolase family members with an antimutator role in Mycobacterium tuberculosis and Mycobacterium smegmatis.

T Dos Vultos1, J Blázquez, J Rauzier, I Matic, B Gicquel.   

Abstract

Mycobacterium tuberculosis and Mycobacterium smegmatis MutT1, MutT2, MutT3, and Rv3908 (MutT4) enzymes were screened for an antimutator role. Results indicate that both MutT1, in M. tuberculosis and M. smegmatis, and MutT4, in M. smegmatis, have that role. Furthermore, an 8-oxo-guanosine triphosphatase function for MutT1 and MutT2 is suggested.

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Year:  2006        PMID: 16585780      PMCID: PMC1446978          DOI: 10.1128/JB.188.8.3159-3161.2006

Source DB:  PubMed          Journal:  J Bacteriol        ISSN: 0021-9193            Impact factor:   3.490


  27 in total

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2.  Structure of a coenzyme A pyrophosphatase from Deinococcus radiodurans: a member of the Nudix family.

Authors:  Lin-Woo Kang; Sandra B Gabelli; Mario A Bianchet; Wen Lian Xu; Maurice J Bessman; L Mario Amzel
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Authors:  Jim Werngren; Sven E Hoffner
Journal:  J Clin Microbiol       Date:  2003-04       Impact factor: 5.948

5.  Studies on the ADP-ribose pyrophosphatase subfamily of the nudix hydrolases and tentative identification of trgB, a gene associated with tellurite resistance.

Authors:  C A Dunn; S F O'Handley; D N Frick; M J Bessman
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7.  Characterization of spontaneous, In vitro-selected, rifampin-resistant mutants of Mycobacterium tuberculosis strain H37Rv.

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Authors:  WenLian Xu; JianYing Shen; Christopher A Dunn; Maurice J Bessman
Journal:  J Biol Chem       Date:  2003-07-18       Impact factor: 5.157

9.  Multidrug-resistant tuberculosis in prison inmates, Azerbaijan.

Authors:  G E Pfyffer; A Strässle; T van Gorkum; F Portaels; L Rigouts; C Mathieu; F Mirzoyev; H Traore; J D van Embden
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10.  Mutations in putative mutator genes of Mycobacterium tuberculosis strains of the W-Beijing family.

Authors:  Mina Ebrahimi-Rad; Pablo Bifani; Carlos Martin; Kristin Kremer; Sofia Samper; Jean Rauzier; Barry Kreiswirth; Jesus Blazquez; Marc Jouan; Dick van Soolingen; Brigitte Gicquel
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  22 in total

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Authors:  S M Arif; A G Patil; U Varshney; M Vijayan
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2.  Crystallization and preliminary X-ray characterization of MutT2, MSMEG_5148 from Mycobacterium smegmatis.

Authors:  S M Arif; P B Sang; U Varshney; M Vijayan
Journal:  Acta Crystallogr F Struct Biol Commun       Date:  2014-01-21       Impact factor: 1.056

3.  A multilayered repair system protects the mycobacterial chromosome from endogenous and antibiotic-induced oxidative damage.

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Review 4.  A new evolutionary and pharmacokinetic-pharmacodynamic scenario for rapid emergence of resistance to single and multiple anti-tuberculosis drugs.

Authors:  Jotam G Pasipanodya; Tawanda Gumbo
Journal:  Curr Opin Pharmacol       Date:  2011-07-30       Impact factor: 5.547

5.  Nucleoside Diphosphate Kinase Escalates A-to-C Mutations in MutT-Deficient Strains of Escherichia coli.

Authors:  Indu Kapoor; Elhassan Ali Fathi Emam; Abhirup Shaw; Umesh Varshney
Journal:  J Bacteriol       Date:  2019-12-06       Impact factor: 3.490

6.  Biochemical properties of MutT2 proteins from Mycobacterium tuberculosis and M. smegmatis and their contrasting antimutator roles in Escherichia coli.

Authors:  Pau Biak Sang; Umesh Varshney
Journal:  J Bacteriol       Date:  2013-01-25       Impact factor: 3.490

7.  Isoxyl activation is required for bacteriostatic activity against Mycobacterium tuberculosis.

Authors:  Jana Korduláková; Yves L Janin; Avraham Liav; Nathalie Barilone; Tiago Dos Vultos; Jean Rauzier; Patrick J Brennan; Brigitte Gicquel; Mary Jackson
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8.  Oxidation of dCTP contributes to antibiotic lethality in stationary-phase mycobacteria.

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Journal:  Proc Natl Acad Sci U S A       Date:  2018-01-30       Impact factor: 11.205

9.  Mycobacterium tuberculosis MutT1 (Rv2985) and ADPRase (Rv1700) proteins constitute a two-stage mechanism of 8-oxo-dGTP and 8-oxo-GTP detoxification and adenosine to cytidine mutation avoidance.

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Journal:  J Biol Chem       Date:  2013-03-05       Impact factor: 5.157

10.  Substrate ambiguity among the nudix hydrolases: biologically significant, evolutionary remnant, or both?

Authors:  Alexander G McLennan
Journal:  Cell Mol Life Sci       Date:  2012-11-27       Impact factor: 9.261

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