| Literature DB >> 11674815 |
G Starkschall1, R E Steadham, R A Popple, S Ahmad, I I Rosen.
Abstract
Commissioning beam data for the convolution/superposition dose-calculation algorithm used in a commercial three-dimensional radiation treatment planning (3D RTP) system (PINNACLE(3), ADAC Laboratories, Milpitas, CA) can be difficult and time consuming. Sixteen adjustable parameters, as well as spectral weights representing a discrete energy spectrum, must be fit to sets of central-axis depth doses and off-axis profiles for a large number of field sizes. This paper presents the beam-commissioning methodology that we used to generate accurate beam models. The methodology is relatively rapid and provides physically reasonable values for beam parameters. The methodology was initiated by using vendor-provided automodeling software to generate a single set of beam parameters that gives an approximate fit to relative dose distributions for all beams, open and wedged, in a data set. A limited number of beam parameters were adjusted by small amounts to give accurate beam models for four open-beam field sizes and three wedged-beam field sizes. Beam parameters for other field sizes were interpolated and validated against measured beam data. Using this methodology, a complete set of beam parameters for a single energy can be generated and validated in approximately 40 h. The resulting parameter values yielded calculated relative doses that matched measured relative doses in a water phantom to within 0.5-1.0% along the central axis and 2% along off-axis beam profiles for field sizes from 4 cmx4 cm to the largest field size available. While the methodology presented is specific to the ADAC PINNACLE(3) treatment planning system, the approach should apply to other implementations of the dose model in other treatment planning system.Entities:
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Year: 2000 PMID: 11674815 PMCID: PMC5726162 DOI: 10.1120/jacmp.v1i1.2651
Source DB: PubMed Journal: J Appl Clin Med Phys ISSN: 1526-9914 Impact factor: 2.102
Figure 1(Color) Central‐axis depth‐dose distribution for electron‐contamination component. Values of parameters are as follows: .
Summary of beam parameters and their effects on calculated beam profiles.
| Parameter | Effect | Magnitude of effect |
|---|---|---|
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| An increase in the spectral weights of the higher energy components increases the central‐axis depth dose at larger depths and decreases the depth dose at shallower depths. | Changing the spectral weight of the highest energy component by as little as 0.001 will have a noticeable effect on the central‐axis depth dose. Different values of spectral weights for the two or three highest energy components are likely to be required for each field size. |
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| Fluence increase/unit distance (cone angle) | An increase in this parameter increases the magnitude of the off‐axis profile at all distances from the central axis. | Changing this parameter by 0.005 will have a noticeable effect on the off‐axis ratio, especially at larger distances from the central axis. The value of this parameter is likely to be insensitive to field size. |
| Fluence cone radius | An increase in the cone radius decreases the magnitude of the off‐axis profile at large distances from the central axis. | The off‐axis ratio is relatively insensitive to the value of this parameter. The cone radius is not a meaningful parameter for small field sizes. |
| Source size | An increase in the source size decreases the slope of the off‐axis profile in the high‐dose gradient region. | Typically a change of 0.1 is required to have a noticeable effect on the slope of the penumbra. The values of these parameters are likely to be insensitive to field size. |
| Gaussian height | An increase in the value of this parameter decreases the sharpness of the transition between the low‐dose gradient region outside the radiation field and the high‐dose gradient region. | The accuracy of monitor unit calculations for elongated fields decreases with an increase in the value of this parameter of around 0.05. The value of this parameter increases with field size. |
| Gaussian width | This parameter has a similar effect on the off‐axis profile as the Gaussian height parameter. | Because of the low value of the Gaussian height parameter required for accurate monitor unit calculations, this parameter has little effect on off‐axis profile. |
| Jaw transmission | An increase in the value of this parameter increases the value of the off‐axis profile in the low‐dose gradient region outside the radiation field. | Changes in this parameter of 0.005 have a noticeable effect on the off‐axis profile in the low‐dose gradient region outside the radiation field. The value of this parameter typically increases with field size. |
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| Modifier Scatter Factor | This parameter affects off‐axis profiles for wedged fields. An increase in the value of this parameter decreases the value of the off‐axis ratio in the region of the thin end of the wedge and increases the off‐axis ratio in the region of the thick end of the wedge. | Changes in this parameter of 0.1 are needed to have a noticeable effect on the off‐axis profile. The value of this parameter typically increases with field size. |
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| Maximum Depth (cm) | The value of this parameter is determined by the energy of the radiation beam and is typically set to be approximately | The exact value of this parameter is not too critical. It is independent of field size. |
| Surface dose (Dose/Fluence) | Increasing the value of this parameter increases the dose at very shallow depths corresponding to the region of electron contamination. | The exact value of this parameter is not critical, as the tolerance of the accuracy of the model near the surface is significantly looser than elsewhere. |
| Depth coefficient (1/cm) ( | Increasing the value of this parameter decreases the amount of electron contamination at depths beyond the surface. | Changes in this parameter of 0.5 are needed to have a noticeable effect on the central‐axis depth dose at shallow depths. |
| Off‐axis coefficient | Increasing this parameter makes the electron contamination component more forward peaked. | Because we have not seen any significant effect of this parameter on the dose distribution we set its value to 0. |
| Depth fraction ( | Increasing the value of this parameter extends the linear portion of the electron contamination to greater depths. | Because we do not use the linear portion of the electron contamination curve for modeling we set this parameter value to 0. |
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| Increasing the value of this parameter decreases the magnitude of the electron contamination curve in the exponential region. | Because we do not use the linear portion of the electron contamination curve for modeling we set this parameter value to 1. |
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| These three parameters affect the field size dependence of the electron contamination. | We use a single set of values determined by the automodeling. |
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| Off‐axis Softening Factor (S) | Increasing the off‐axis softening parameter increases the value of the off‐axis profile at large distances from the central axis for shallow depths. | Changes in the value of this parameter of 0.01 are observable in the off‐axis profiles. The value of this parameter is typically independent of field size. |
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| Fluence grid resolution, Phantom size—lateral Phantom size—depth | The values of these parameters are determined by the geometry of the beam. |
Beam parameters for a Mevatron 6740 6‐MV photon beam.
| Energy spectrum | Generic Automodeled | |
|---|---|---|
| Energy (MeV) | Relative photon weights | |
| 0.10 | 0.059 | 0.057 |
| 0.20 | 0.102 | 0.100 |
| 0.30 | 0.139 | 0.137 |
| 0.40 | 0.172 | 0.169 |
| 0.50 | 0.199 | 0.196 |
| 0.60 | 0.223 | 0.219 |
| 0.80 | 0.257 | 0.253 |
| 1.00 | 0.279 | 0.273 |
| 1.25 | 0.290 | 0.283 |
| 1.50 | 0.289 | 0.281 |
| 2.00 | 0.260 | 0.251 |
| 3.00 | 0.165 | 0.157 |
| 4.00 | 0.082 | 0.076 |
| 5.00 | 0.032 | 0.028 |
| 6.00 | 0.010 | 0.007 |
| 8.00 | 0.000 | 0.000 |
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| Incident fluence increase/cm | 0.00852307 | 0.0115108 |
| Incident fluence cone radius (cm) | 13.3592 | 14.587 |
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| 0.1025 | 0.23875 |
|
| 0.11375 | 0.07625 |
| Gaussian height (cm) | 0.0790897 | 0.089879 |
| Gaussian width (cm) | 0.824079 | 0.895998 |
| Jaw transmission | 0.0100608 | 0.00673947 |
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| Modifier scatter factor | 0.2 | 0.2 |
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| Maximum depth (cm) | 2.5 | 2.5 |
| Surface dose (dose/fluence) | 0.0005 | 0.0005 |
| Depth coefficient (1/cm) | 0.3 | 0.3 |
| Off‐axis coefficient | 0 | 0 |
|
| 0 | 0 |
|
| 1 | 1 |
|
| 0.00193502 | 0.00193502 |
|
| 0.0661798 | 0.0661798 |
|
| 0.00375271 | 0.00375271 |
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| Off‐axis softening factor | 4.53797 | 0.140592 |
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| Fluence grid resolution (cm) | 0.40 | 0.40 |
| Phantom size–lateral (cm) | 50.00 | 50.00 |
| Phantom size–depth (cm) | 50.00 | 50.00 |
Field‐size specific beam parameters for open fields.
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| field | field | field | field | field | |
| Energy (MeV) | Relative photon weights | ||||
| 0.10 | 0.057 | 0.057 | 0.057 | 0.057 | 0.057 |
| 0.20 | 0.100 | 0.100 | 0.100 | 0.100 | 0.100 |
| 0.30 | 0.137 | 0.137 | 0.137 | 0.137 | 0.137 |
| 0.40 | 0.169 | 0.169 | 0.169 | 0.169 | 0.169 |
| 0.50 | 0.196 | 0.196 | 0.196 | 0.196 | 0.196 |
| 0.60 | 0.219 | 0.219 | 0.219 | 0.219 | 0.219 |
| 0.80 | 0.253 | 0.253 | 0.253 | 0.253 | 0.253 |
| 1.00 | 0.273 | 0.273 | 0.273 | 0.273 | 0.273 |
| 1.25 | 0.283 | 0.283 | 0.283 | 0.283 | 0.283 |
| 1.50 | 0.281 | 0.281 | 0.281 | 0.281 | 0.281 |
| 2.00 | 0.251 | 0.251 | 0.251 | 0.251 | 0.251 |
| 3.00 | 0.157 | 0.157 | 0.157 | 0.157 | 0.157 |
| 4.00 | 0.076 | 0.076 | 0.076 | 0.076 | 0.076 |
| 5.00 | 0.030 | 0.025 | 0.025 | 0.025 | 0.025 |
| 6.00 | 0.005 | 0.005 | 0.005 | 0.005 | 0.005 |
| 8.00 | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 |
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| Incident fluence increase/cm | 0.016 | 0.016 | 0.016 | 0.013 | 0.011 |
| Incidence fluence cone radius (cm) | 3 | 3 | 5 | 9 | 15 |
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| 0.1 | 0.1 | 0.1 | 0.1 | 0.1 |
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| 0.1 | 0.1 | 0.1 | 0.1 | 0.1 |
| Gaussian height (cm) | 0.03 | 0.03 | 0.03 | 0.03 | 0.03 |
| Gaussian width (cm) | 1.3 | 1.3 | 1.3 | 1.3 | 1.3 |
| Jaw transmission | 0.01 | 0.02 | 0.03 | 0.04 | 0.05 |
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| Modifier scatter factor | 0.2 | 0.2 | 0.2 | 0.2 | 0.2 |
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| Maximum depth (cm) | 2.5 | 2.5 | 2.5 | 2.5 | 2.5 |
| Surface dose (dose/fluence) | 0.22 | 0.22 | 0.22 | 0.22 | 0.22 |
| Depth coefficient (1/cm) | 3.2 | 3.2 | 3.2 | 3.2 | 3.2 |
| Off‐axis coefficient | 0 | 0 | 0 | 0 | 0 |
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| 0 | 0 | 0 | 0 | 0 |
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| 1 | 1 | 1 | 1 | 1 |
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| 0.015 | 0.015 | 0.015 | 0.015 | 0.015 |
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| 0.07 | 0.07 | 0.07 | 0.07 | 0.07 |
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| 0.07 | 0.07 | 0.07 | 0.07 | 0.07 |
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| Off‐axis softening factor | 0 | 0 | 0 | 0 | 0 |
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| Fluence grid resolution (cm) | 0.40 | 0.40 | 0.40 | 0.40 | 0.40 |
| Phantom size—lateral (cm) | 50.00 | 50.00 | 50.00 | 60.00 | 70.00 |
| Phantom size—depth (cm) | 50.00 | 50.00 | 50.00 | 50.00 | 50.00 |
Maximum deviation between calculated and measured dose profiles. “Inside beam” refers to points inside the beam penumbra for which the dose gradient is small, while “outside beam” refers to points outside the penumbra for which the dose gradient is small.
| Central axis | Off‐axis inside beam | Off‐axis outside beam | |||||||
|---|---|---|---|---|---|---|---|---|---|
| Field size (cm) |
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| 35 cm |
| 35 cm | Penumbra |
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| 1.80 | 2.5% | 0.2% | 0.3% | 0.5% | 0.3% | 1.1% | 1.3% |
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| 1.60 | 2.1% | 0.2% | 0.3% | 1.0% | 0.2% | 1.4% | 2.1% |
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| 1.60 | 1.7% | 0.4% | 0.3% | 1.2% | 0.7% | 1.8% | 2.2% | 1 mm |
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| 1.60 | 1.5% | 0.3% | 0.2% | 1.0% | 1.1% | 1.3% | 1.9% |
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| 1.60 | 1.4% | 0.3% | 0.2% | 1.0% | 1.6% | 1.5% | 2.0% | 1 mm |
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| 1.60 | 1.5% | 0.3% | 0.2% | 1.2% | 1.5% | 2.0% | 1.9% | 1 mm |
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| 1.60 | 1.3% | 0.3% | 0.2% | 1.0% | 1.2% | 1.7% | 2.7% | 1 mm |
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| 1.60 | 0.7% | 0.3% | 0.1% | 1.0% | 1.4% | 1.6% | 2.5% | 1 mm |
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| 1.50 | 0.5% | 0.3% | 0.2% | 1.2% | 1.3% | 2.2% | 3.0% | 1 mm |
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| 1.50 | 1.0% | 0.5% | 0.2% | 0.8% | 1.4% | 1.8% | 3.0% | 1 mm |
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| 1.45 | 0.7% | 0.3% | 0.2% | 1.9% | 3.1% | 2.5% | 3.7% | 2 mm |
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| 1.40 | 0.5% | 0.6% | 0.2% | 2.5% | 3.9% | 2.8% | 4.6% | 2 mm |
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| 1.30 | 0.7% | 1.0% | 0.3% | 3.2% | 4.5% | 3.2% | 5.6% | 3 mm |
Figure 2(Color) Isodose distributions for a open field. The calculated dose distribution is indicated in color, and the measured dose distribution is indicated in black and white.
Beam parameters for 60° wedged fields.
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|---|---|---|---|
| Energy spectrum | field | field | field |
| Energy (MeV) | Relative photon weights | ||
| 0.10 | 0.057 | 0.057 | 0.057 |
| 0.20 | 0.100 | 0.100 | 0.100 |
| 0.30 | 0.137 | 0.137 | 0.137 |
| 0.40 | 0.169 | 0.169 | 0.169 |
| 0.50 | 0.196 | 0.196 | 0.196 |
| 0.60 | 0.219 | 0.219 | 0.219 |
| 0.80 | 0.253 | 0.253 | 0.253 |
| 1.00 | 0.273 | 0.273 | 0.273 |
| 1.25 | 0.283 | 0.283 | 0.283 |
| 1.50 | 0.281 | 0.281 | 0.281 |
| 2.00 | 0.251 | 0.251 | 0.251 |
| 3.00 | 0.157 | 0.157 | 0.157 |
| 4.00 | 0.076 | 0.076 | 0.076 |
| 5.00 | 0.025 | 0.008 | 0.008 |
| 6.00 | 0.005 | 0.000 | 0.000 |
| 8.00 | 0.000 | 0.000 | 0.000 |
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| Incident fluence increase/cm | 0.012 | 0.012 | 0.014 |
| Incident fluence cone radius (cm) | 3 | 3 | 4 |
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| 0.1 | 0.1 | 0.1 |
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| 0.1 | 0.1 | 0.1 |
| Gaussian height (cm) | 0.03 | 0.03 | 0.03 |
| Gaussian width (cm) | 1.3 | 1.3 | 1.3 |
| Jaw transmission | 0.02 | 0.03 | 0.05 |
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| Modifier scatter factor | 0.12 | 0.12 | 0.20 |
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| Maximum depth (cm) | 2.5 | 2.5 | 2.5 |
| Surface dose (dose/fluence) | 1.0 | 1.0 | 1.0 |
| Depth coefficient (1/cm) | 9.9 | 9.9 | 9.9 |
| Off‐axis coefficient | 0 | 0 | 0 |
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| 0 | 0 | 0 |
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| 1 | 1 | 1 |
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| 0.05 | 0.05 | 0.05 |
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| 0.8 | 0.8 | 0.8 |
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| 0.1 | 0.1 | 0.1 |
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| Off‐axis softening factor | 0.004 | 0.004 | 0.004 |
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| Fluence grid resolution (cm) | 0.40 | 0.40 | 0.40 |
| Phantom size—lateral (cm) | 50.00 | 50.00 | 50.00 |
| Phantom size—depth (cm) | 50.00 | 50.00 | 50.00 |
Maximum deviation between calculated and measured dose profiles for 60° wedged fields. Maximum difference at depth of 1.5 cm. Calculated value at other depths within 2.0% of measurement. Maximum difference at depth of 1.5 cm. Calculated value at other depths within 2.5% of measurement.
| Central axis | Off‐axis inside beam | Off‐axis outside beam | |||||||
|---|---|---|---|---|---|---|---|---|---|
| Field Size (cm) |
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| 35 cm |
| 35 cm | Penumbra |
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| 1.70 | 3.7% | 0.4% | 0.6% | 1.9% | 1.8% | 0.9% | 0.7% |
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| 1.70% | 3.8% | 0.5% | 0.7% | 2.9%a | 2.3% | 1.0% | 1.6% |
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| 1.75 | 4.1% | 0.5% | 0.8% | 2.5%a | 2.1% | 1.3% | 1.8% |
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| 1.80 | 4.3% | 0.3% | 0.8% | 3.2%b | 2.4% | 1.2% | 1.7% |
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| 1.70 | 4.1% | 0.6% | 1.0% | 3.2% | 1.7% | 1.3% | 2.0% | 1 mm |
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| 1.70 | 5.0% | 0.5% | 0.9% | 1.6% | 1.8% | 2.4% | 2.5% | 1 mm |
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| 1.60 | 2.3% | 0.4% | 1.0% | 2.5% | 1.5% | 3.4% | 3.0% | 2 mm |
Figure 3(Color) Isodose distributions for a 60° wedged field. The calculated dose distribution is indicated in color and the measured dose distribution is indicated in black and white.