Literature DB >> 11509259

Population genomics: linkage disequilibrium holds the key.

D B Goldstein1, M E Weale.   

Abstract

Current efforts to find disease-causing genes depend on patterns of linkage disequilibrium in human populations. Recent work has shown that linkage disequilibrium can extend over much larger genomic regions than expected, and that the patterns of linkage disequilibrium can differ markedly among populations.

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Mesh：

Year:  2001        PMID： 11509259     DOI： 10.1016/s0960-9822(01)00348-7

Source DB:  PubMed          Journal:  Curr Biol        ISSN： 0960-9822            Impact factor:   10.834


  35 in total

1.  Linkage disequilibrium and sequence diversity in a 500-kbp region around the adh1 locus in elite maize germplasm.

Authors:  Mark Jung; Ada Ching; Dinakar Bhattramakki; Maureen Dolan; Scott Tingey; Michelle Morgante; Antoni Rafalski
Journal:  Theor Appl Genet       Date:  2004-08       Impact factor: 5.699

2.  Locked nucleic acid (LNA) single nucleotide polymorphism (SNP) genotype analysis and validation using real-time PCR.

Authors:  Matthew P Johnson; Larisa M Haupt; Lyn R Griffiths
Journal:  Nucleic Acids Res       Date:  2004-03-26       Impact factor: 16.971

3.  Nucleotide diversity and linkage disequilibrium in cold-hardiness- and wood quality-related candidate genes in Douglas fir.

Authors:  Konstantin V Krutovsky; David B Neale
Journal:  Genetics       Date:  2005-09-12       Impact factor: 4.562

Review 4.  Genetic approaches to solving common diseases.

Authors:  P M Abou-Sleiman; D G Healy; N W Wood
Journal:  J Neurol       Date:  2004-10       Impact factor: 4.849

5.  Intra- and interpopulation genotype reconstruction from tagging SNPs.

Authors:  Peristera Paschou; Michael W Mahoney; Asif Javed; Judith R Kidd; Andrew J Pakstis; Sheng Gu; Kenneth K Kidd; Petros Drineas
Journal:  Genome Res       Date:  2006-12-06       Impact factor: 9.043

Review 6.  Systems biology and heart failure: concepts, methods, and potential research applications.

Authors:  Kirkwood F Adams
Journal:  Heart Fail Rev       Date:  2010-07       Impact factor: 4.214

7.  Why Do Different Individuals Progress Along Different Life Trajectories?

Authors:  Gregory T Smith
Journal:  Perspect Psychol Sci       Date:  2009-07

8.  Porcine ubiquitin-like 5 (UBL5) gene: genomic organization, polymorphisms, mRNA cloning, splicing variants and association study.

Authors:  Martin Masopust; Filip Weisz; Heinz Bartenschlager; Aleš Knoll; Zuzana Vykoukalová; Hermann Geldermann; Stanislav Cepica
Journal:  Mol Biol Rep       Date:  2014-01-24       Impact factor: 2.316

9.  Genetic association between intronic variants in AS3MT and arsenic methylation efficiency is focused on a large linkage disequilibrium cluster in chromosome 10.

Authors:  Paulina Gomez-Rubio; Maria M Meza-Montenegro; Ernesto Cantu-Soto; Walter T Klimecki
Journal:  J Appl Toxicol       Date:  2010-04       Impact factor: 3.446

10.  Genotype-phenotype analysis of the Crohn's disease susceptibility haplotype on chromosome 5q31.

Authors:  A Armuzzi; T Ahmad; K-L Ling; A de Silva; S Cullen; D van Heel; T R Orchard; K I Welsh; S E Marshall; D P Jewell
Journal:  Gut       Date:  2003-08       Impact factor: 23.059
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