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Literature DB >> 1140623

Effect of metiamide on the response to secretin and cholecystokinin in man.

Abstract

The effects of intravenous metiamide on the pancreatic exocrine response to intravenous infusion of secretin plus cholecystokinin has been studied in eight patients with duodenal ulceration. The secretion of bicarbonate and water was not altered by metiamide. The secretion of enzymes was significantly less than control during infusion of metiamide. The differences between the pancreatic and gastric responses to metiamide are discussed.

Entities: Chemical Disease Gene Species

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Year: 1975 PMID： 1140623 PMCID： PMC1410936 DOI： 10.1136/gut.16.1.33

Source DB: PubMed Journal: Gut ISSN： 0017-5749 Impact factor: 23.059

6 in total

1. A method for estimating peptic activity in gastric contents.

Authors: J N Hunt
Journal: Biochem J Date: 1948 Impact factor: 3.857

2. Effects of a gastrin-like pentapeptide (I.C.I. 50,123) on stomach and pancreas.

Authors: K G Wormsley; M P Mahoney; M Ng
Journal: Lancet Date: 1966-05-07 Impact factor: 79.321

3. Inhibition of nocturnal acid secretion in duodenal ulcer by one oral dose of metiamide.

Authors: G J Milton-Thompson; J G Williams; D J Jenkins; J J Misiewicz
Journal: Lancet Date: 1974-04-20 Impact factor: 79.321

4. The effect of histamine (H2-) receptor blockade on vagally-induced gastric secretion in man.

Authors: D C Carter; M Werner; J H Forrest; R C Heading; J Park; D J Shearman
Journal: Scott Med J Date: 1974-05 Impact factor: 0.729

5. Further studies of gastric hypersecretion in chronic renal failure.

Authors: A M Shepherd; W K Stewart; B Thjodleifsson; K G Wormsley
Journal: Br Med J Date: 1974-01-19

6. Gastric response to metiamide.

Authors: B Thjodleifsson; K G Wormsley
Journal: Br Med J Date: 1974-05-11

6 in total

8 in total

Effect of metiamide on the response to secretin and cholecystokinin in man.

1. A method for estimating peptic activity in gastric contents.

2. Effects of a gastrin-like pentapeptide (I.C.I. 50,123) on stomach and pancreas.

3. Inhibition of nocturnal acid secretion in duodenal ulcer by one oral dose of metiamide.

4. The effect of histamine (H2-) receptor blockade on vagally-induced gastric secretion in man.

5. Further studies of gastric hypersecretion in chronic renal failure.

6. Gastric response to metiamide.

1. Histamine receptors in unstimulated pancreatic exocrine secretion of the rabbit.

2. Cimetidine and postprandial pancreatic exocrine secretion in dogs.

3. Classification and biological distribution of histamine receptor sub-types.

4. Classification and biological distribution of histamine receptor sub-types. 1975.

5. Cimetidine: effect on pancreatic and biliary function in man.

6. Histamine stimulation of digestive enzyme secretion by in vitro rabbit pancreas.

7. Effect of ranitidine, a new H2-antagonist, on gastric and pancreatic secretion in duodenal ulcer patients.

8. Postprandial biliary and pancreatic secretion during profound inhibition of gastric secretion in humans.