Literature DB >> 11371745

Implications of 2,457 consecutive surgical infections entering year 2000.

R G Sawyer1, D P Raymond, S J Pelletier, T D Crabtree, T G Gleason, T L Pruett.   

Abstract

OBJECTIVE: To assess the demographics and characteristics of infections in surgical patients to define areas that deserve emphasis in surgical education. SUMMARY BACKGROUND DATA: As a result of evolving technology and diseases, the complexity of diagnosing and treating infections has increased during the past three decades for all patients, including those treated primarily by surgeons. No comprehensive analysis of these conditions in a single surgical cohort has been recently published.
METHODS: The authors conducted a prospective, observational study of all infections occurring on the general and trauma surgery services at a single university hospital during a 3.5-year period.
RESULTS: The authors identified 2,457 infections: 608 community-acquired, 1,053 occurring on the wards, and 796 occurring in the intensive care unit. Although dependent on patient location, the most common sites were abdomen, lung, and wound; the most common isolates were Staphylococcus epidermidis, Staphylococcus aureus, and Candida albicans; and the most commonly used antibiotics were ciprofloxacin, vancomycin, and metronidazole. The overall death rate was 13%, ranging from 5% after community-acquired infections to 25% after infections acquired in the intensive care unit.
CONCLUSIONS: Most infections treated by surgeons are hospital-acquired. Infections with gram-positive cocci and fungi are common, with pulmonary infections becoming more common. Fluoroquinolones have become important therapeutic agents. Depending on the type of practice, these data should be helpful to direct educational efforts so that surgeons can remain knowledgeable and active in the nonsurgical care of their patients.

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Year:  2001        PMID: 11371745      PMCID: PMC1421331          DOI: 10.1097/00000658-200106000-00018

Source DB:  PubMed          Journal:  Ann Surg        ISSN: 0003-4932            Impact factor:   12.969


  12 in total

1.  Waiting for microbiologic data to direct therapy against nosocomial infections in febrile surgical patients: are outcomes worsened?

Authors:  S J Pelletier; T D Crabtree; T G Gleason; L E Banas; S R Patel; T L Pruett; R G Sawyer
Journal:  Arch Surg       Date:  1999-12

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Authors:  A Oberholzer; M Keel; R Zellweger; U Steckholzer; O Trentz; W Ertel
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3.  Bacteremia associated with central venous catheter infection is not an independent predictor of outcomes.

Authors:  S J Pelletier; T D Crabtree; T G Gleason; T L Pruett; R G Sawyer
Journal:  J Am Coll Surg       Date:  2000-06       Impact factor: 6.113

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Authors:  W A Knaus; E A Draper; D P Wagner; J E Zimmerman
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5.  Guideline for Prevention of Surgical Site Infection, 1999. Centers for Disease Control and Prevention (CDC) Hospital Infection Control Practices Advisory Committee.

Authors:  A J Mangram; T C Horan; M L Pearson; L C Silver; W R Jarvis
Journal:  Am J Infect Control       Date:  1999-04       Impact factor: 2.918

6.  Incidence and mortality of severe sepsis in surgical intensive care patients: the influence of patient gender on disease process and outcome.

Authors:  M W Wichmann; D Inthorn; H J Andress; F W Schildberg
Journal:  Intensive Care Med       Date:  2000-02       Impact factor: 17.440

7.  Prediction of poorer prognosis by infection with antibiotic-resistant gram-positive cocci than by infection with antibiotic-sensitive strains.

Authors:  T G Gleason; T D Crabtree; S J Pelletier; D P Raymond; T B Karchmer; T L Pruett; R G Sawyer
Journal:  Arch Surg       Date:  1999-10

8.  CDC definitions for nosocomial infections, 1988.

Authors:  J S Garner; W R Jarvis; T G Emori; T C Horan; J M Hughes
Journal:  Am J Infect Control       Date:  1988-06       Impact factor: 2.918

9.  Male gender is a risk factor for major infections after surgery.

Authors:  P J Offner; E E Moore; W L Biffl
Journal:  Arch Surg       Date:  1999-09

Review 10.  Toward an epidemiology and natural history of SIRS (systemic inflammatory response syndrome)

Authors:  R C Bone
Journal:  JAMA       Date:  1992 Dec 23-30       Impact factor: 56.272

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Review 2.  Prebiotics, probiotics, synbiotics in surgery--are they only trendy, truly effective or even dangerous?

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3.  Mannose-binding lectin deficiency facilitates abdominal Candida infections in patients with secondary peritonitis.

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4.  Nosocomial infections after peripheral arterial bypass surgery.

Authors:  Arianne Ploeg; Christopher Lange; Jan-Willem Lardenoye; Paul Breslau
Journal:  World J Surg       Date:  2007-08       Impact factor: 3.352

Review 5.  Single-drug therapy or selective decontamination of the digestive tract as antifungal prophylaxis in critically ill patients: a systematic review.

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Journal:  Crit Care       Date:  2007       Impact factor: 9.097

6.  Surgical site infection in critically ill patients with secondary and tertiary peritonitis: epidemiology, microbiology and influence in outcomes.

Authors:  Josep Ballus; Juan C Lopez-Delgado; Joan Sabater-Riera; Xose L Perez-Fernandez; A J Betbese; J A Roncal
Journal:  BMC Infect Dis       Date:  2015-07-30       Impact factor: 3.090

7.  Examination of Risk Factors for the Development of Surgical Site Infections.

Authors:  Slobodan Stanic; Janja Bojanic; Predrag Grubor; Biljana Mijovic; Veljko Maric
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  7 in total

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