Literature DB >> 11353602

Oxacillinase-mediated resistance to cefepime and susceptibility to ceftazidime in Pseudomonas aeruginosa.

D Aubert1, L Poirel, J Chevalier, S Leotard, J M Pages, P Nordmann.   

Abstract

Pseudomonas aeruginosa clinical isolate SOF-1 was resistant to cefepime and susceptible to ceftazidime. This resistance phenotype was explained by the expression of OXA-31, which shared 98% amino acid identity with a class D beta-lactamase, OXA-1. The oxa-31 gene was located on a ca. 300-kb nonconjugative plasmid and on a class 1 integron. No additional efflux mechanism for cefepime was detected in P. aeruginosa SOF-1. Resistance to cefepime and susceptibility to ceftazidime in P. aeruginosa were conferred by OXA-1 as well.

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Year:  2001        PMID： 11353602      PMCID： PMC90522          DOI： 10.1128/AAC.45.6.1615-1620.2001

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  32 in total

1.  Characterization of the nonenzymatic chloramphenicol resistance (cmlA) gene of the In4 integron of Tn1696: similarity of the product to transmembrane transport proteins.

Authors:  L Bissonnette; S Champetier; J P Buisson; P H Roy
Journal:  J Bacteriol       Date:  1991-07       Impact factor: 3.490

2.  Precise insertion of antibiotic resistance determinants into Tn21-like transposons: nucleotide sequence of the OXA-1 beta-lactamase gene.

Authors:  M Ouellette; L Bissonnette; P H Roy
Journal:  Proc Natl Acad Sci U S A       Date:  1987-11       Impact factor: 11.205

3.  New plasmid-mediated oxacillin-hydrolyzing beta-lactamase in Pseudomonas aeruginosa.

Authors:  A M Philippon; G C Paul; G A Jacoby
Journal:  J Antimicrob Chemother       Date:  1986-04       Impact factor: 5.790

4.  Plasmid expansion?

Authors:  A Vivian
Journal:  Microbiology       Date:  1994-02       Impact factor: 2.777

5.  Revised analysis of aadA2 gene of plasmid pSa.

Authors:  A Bito; M Susani
Journal:  Antimicrob Agents Chemother       Date:  1994-05       Impact factor: 5.191

6.  pBBR1MCS: a broad-host-range cloning vector.

Authors:  M E Kovach; R W Phillips; P H Elzer; R M Roop; K M Peterson
Journal:  Biotechniques       Date:  1994-05       Impact factor: 1.993

7.  beta-lactamases in Shigella flexneri isolates from Hong Kong and Shanghai and a novel OXA-1-like beta-lactamase, OXA-30.

Authors:  L K Siu; J Y Lo; K Y Yuen; P Y Chau; M H Ng; P L Ho
Journal:  Antimicrob Agents Chemother       Date:  2000-08       Impact factor: 5.191

8.  Diversity and relative strength of tandem promoters for the antibiotic-resistance genes of several integrons.

Authors:  C Lévesque; S Brassard; J Lapointe; P H Roy
Journal:  Gene       Date:  1994-05-03       Impact factor: 3.688

9.  Comparison of the sequences of class A beta-lactamases and of the secondary structure elements of penicillin-recognizing proteins.

Authors:  B Joris; P Ledent; O Dideberg; E Fonzé; J Lamotte-Brasseur; J A Kelly; J M Ghuysen; J M Frère
Journal:  Antimicrob Agents Chemother       Date:  1991-11       Impact factor: 5.191

10.  A comparative study of class-D beta-lactamases.

Authors:  P Ledent; X Raquet; B Joris; J Van Beeumen; J M Frère
Journal:  Biochem J       Date:  1993-06-01       Impact factor: 3.857
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  32 in total

1.  Novel 3-N-aminoglycoside acetyltransferase gene, aac(3)-Ic, from a Pseudomonas aeruginosa integron.

Authors:  Maria Letizia Riccio; Jean-Denis Docquier; Emanuela Dell'Amico; Francesco Luzzaro; Gianfranco Amicosante; Gian Maria Rossolini
Journal:  Antimicrob Agents Chemother       Date:  2003-05       Impact factor: 5.191

2.  blaCTX-M-2 is located in an unusual class 1 integron (In35) which includes Orf513.

Authors:  Sonia M Arduino; Paul H Roy; George A Jacoby; Betina E Orman; Silvia A Pineiro; Daniela Centron
Journal:  Antimicrob Agents Chemother       Date:  2002-07       Impact factor: 5.191

3.  Decreased susceptibility to cefepime in a clinical strain of Escherichia coli related to plasmid- and integron-encoded OXA-30 beta-lactamase.

Authors:  Véronique Dubois; Corinne Arpin; Claudine Quentin; Jeannette Texier-Maugein; Laurent Poirel; Patrice Nordmann
Journal:  Antimicrob Agents Chemother       Date:  2003-07       Impact factor: 5.191

Review 4.  Modes and modulations of antibiotic resistance gene expression.

Authors:  Florence Depardieu; Isabelle Podglajen; Roland Leclercq; Ekkehard Collatz; Patrice Courvalin
Journal:  Clin Microbiol Rev       Date:  2007-01       Impact factor: 26.132

5.  OXA-58, a novel class D {beta}-lactamase involved in resistance to carbapenems in Acinetobacter baumannii.

Authors:  Laurent Poirel; Sophie Marqué; Claire Héritier; Christine Segonds; Gérard Chabanon; Patrice Nordmann
Journal:  Antimicrob Agents Chemother       Date:  2005-01       Impact factor: 5.191

Review 6.  Global challenge of multidrug-resistant Acinetobacter baumannii.

Authors:  Federico Perez; Andrea M Hujer; Kristine M Hujer; Brooke K Decker; Philip N Rather; Robert A Bonomo
Journal:  Antimicrob Agents Chemother       Date:  2007-07-23       Impact factor: 5.191

7.  Evaluation and updating of the Osiris expert system for identification of Escherichia coli beta-lactam resistance phenotypes.

Authors:  Frédéric Bert; Manette Juvin; Zahia Ould-Hocine; Gervais Clarebout; Emmanuelle Keller; Nicole Lambert; Guillaume Arlet
Journal:  J Clin Microbiol       Date:  2005-04       Impact factor: 5.948

8.  Evaluation of the VITEK 2 advanced expert system for reporting piperacillin susceptibility in Klebsiella spp.

Authors:  So-Young Lee; Jin Kyung Yu; Sang Yoon Lee; Sang Hyun Shin; Hae-Il Park; Eun-Jee Oh; Yeon-Joon Park
Journal:  Antimicrob Agents Chemother       Date:  2008-04-07       Impact factor: 5.191

Review 9.  Updated functional classification of beta-lactamases.

Authors:  Karen Bush; George A Jacoby
Journal:  Antimicrob Agents Chemother       Date:  2009-12-07       Impact factor: 5.191

10.  Genetic and biochemical characterization of a chromosome-encoded carbapenem-hydrolyzing ambler class D beta-lactamase from Shewanella algae.

Authors:  Claire Héritier; Laurent Poirel; Patrice Nordmann
Journal:  Antimicrob Agents Chemother       Date:  2004-05       Impact factor: 5.191
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