| Literature DB >> 12069995 |
Sonia M Arduino1, Paul H Roy, George A Jacoby, Betina E Orman, Silvia A Pineiro, Daniela Centron.
Abstract
Examination of the bla(CTX-M-2) gene in plasmid pMAR-12 by sequencing and PCR analysis revealed that the bla gene and the surrounding DNA, which is closely related (99% homology) to the Kluyvera ascorbata chromosomal DNA that contains the bla(KLUA-1) gene, are located in a complex sul1-type integron, termed In35, that includes Orf513. It is possible that bla(CTX-M-2) was acquired by plasmid pMAR-12 through an uncharacterized recombinational event in which Orf513 could be involved.Entities:
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Year: 2002 PMID: 12069995 PMCID: PMC127297 DOI: 10.1128/AAC.46.7.2303-2306.2002
Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN: 0066-4804 Impact factor: 5.191