Literature DB >> 11066140

Logistics and technique for procurement of intestinal, pancreatic, and hepatic grafts from the same donor.

K Abu-Elmagd1, J Fung, J Bueno, D Martin, J R Madariaga, G Mazariegos, G Bond, E Molmenti, R J Corry, T E Starzl, J Reyes.   

Abstract

OBJECTIVE: To assess a technique for simultaneous recovery of the intestine, pancreas, and liver from the same donor. SUMMARY BACKGROUND DATA: With the more frequent use of pancreatic and intestinal transplantation, a procurement procedure is needed that permits retrieval of both organs as well as the liver from the same cadaveric donor for transplantation to different recipients. It is believed by many procurement officers and surgeons, however, that this objective is not technically feasible.
METHODS: A technique for simultaneous recovery of the intestine, pancreas, and liver was used in 13 multiorgan cadaver donors during a 26-month period, with transplantation of the organs to 33 recipients. The intestine was removed from 11 donors separately and in continuity with the pancreas in the other 2. Six additional pancreases were excised and transplanted separately. Thirteen livers were retrieved, one of which was discarded because of steatorrhea. Ten of the remaining 12 livers were transplanted intact; the other 2 were split in situ and used as reduced-size hepatic allografts in four recipients.
RESULTS: None of the 11 intestinal, 6 pancreatic, 2 intestinal-pancreatic, or 14 whole or partial liver allografts sustained serious ischemic injury or were lost as a result of technical complications. One liver recipient died 25 months after surgery of recurrent C virus hepatitis. The other 32 recipients had adequate allograft function with a mean follow-up of 8 months.
CONCLUSION: It was possible using the described technique to retrieve intestine, pancreas, and liver allografts safely from the same donor and to transplant these organs to different recipients.

Entities:  

Mesh:

Substances:

Year:  2000        PMID: 11066140      PMCID: PMC1421222          DOI: 10.1097/00000658-200011000-00010

Source DB:  PubMed          Journal:  Ann Surg        ISSN: 0003-4932            Impact factor:   12.969


  17 in total

1.  Evolution of clinical intestinal transplantation: improved outcome and cost effectiveness.

Authors:  K M Abu-Elmagd; J Reyes; J J Fung; G Mazariegos; J Bueno; C Janov; J Colangelo; A Rao; A Demetris; T E Starzl
Journal:  Transplant Proc       Date:  1999 Feb-Mar       Impact factor: 1.066

2.  Intestinal transplantation: 1997 report of the international registry. Intestinal Transplant Registry.

Authors:  D Grant
Journal:  Transplantation       Date:  1999-04-15       Impact factor: 4.939

3.  A new technique for en bloc liver and pancreas harvesting.

Authors:  J P Squifflet; B de Hemptinne; P Gianello; P Balladur; J B Otte; G P Alexandre
Journal:  Transplant Proc       Date:  1990-08       Impact factor: 1.066

4.  Clinical intestinal transplantation: new perspectives and immunologic considerations.

Authors:  K Abu-Elmagd; J Reyes; S Todo; A Rao; R Lee; W Irish; H Furukawa; J Bueno; J McMichael; A T Fawzy; N Murase; J Demetris; J Rakela; J J Fung; T E Starzl
Journal:  J Am Coll Surg       Date:  1998-05       Impact factor: 6.113

5.  Combined whole pancreas and liver retrieval: comparison between Y-iliac graft and splenomesenteric anastomosis.

Authors:  L Fernández-Cruz; E Astudillo; H Sanfey; J M Llovera; A Saenz; M A Lopez-Boado; C Bagur
Journal:  Transpl Int       Date:  1992-03       Impact factor: 3.782

6.  Advantages of the rapid en bloc technique for pancreas/liver recovery.

Authors:  F Dodson; A Pinna; N Jabbour; A Casavilla; F Khan; R Corry
Journal:  Transplant Proc       Date:  1995-12       Impact factor: 1.066

7.  A flexible procedure for multiple cadaveric organ procurement.

Authors:  T E Starzl; T R Hakala; B W Shaw; R L Hardesty; T J Rosenthal; B P Griffith; S Iwatsuki; H T Bahnson
Journal:  Surg Gynecol Obstet       Date:  1984-03

8.  Simultaneous administration of adjuvant donor bone marrow in pancreas transplant recipients.

Authors:  R J Corry; P K Chakrabarti; R Shapiro; A S Rao; I Dvorchik; M L Jordan; V P Scantlebury; C A Vivas; J J Fung; T E Starzl
Journal:  Ann Surg       Date:  1999-09       Impact factor: 12.969

9.  Tacrolimus in pancreas transplantation: a multicenter analysis. Tacrolimus Pancreas Transplant Study Group.

Authors:  R W Gruessner
Journal:  Clin Transplant       Date:  1997-08       Impact factor: 2.863

10.  Procurement and preparation of human isolated small intestinal grafts for transplantation.

Authors:  R Sindhi; I J Fox; T Heffron; B W Shaw; A N Langnas
Journal:  Transplantation       Date:  1995-10-27       Impact factor: 4.939

View more
  18 in total

Review 1.  Small intestinal transplantation.

Authors:  E M Quigley
Journal:  Curr Gastroenterol Rep       Date:  2001-10

2.  Modified technique for combined liver-small bowel transplantation in pigs.

Authors:  Zhen-Yu Yin; Xiao-Dong Ni; Feng Jiang; Ning Li; You-Sheng Li; Jie-Shou Li
Journal:  World J Gastroenterol       Date:  2003-07       Impact factor: 5.742

3.  Auxiliary en-bloc liver-small bowel transplantation with partial pancreas preservation in pigs.

Authors:  Zhen-Yu Yin; Xiao-Dong Ni; Feng Jiang; Ning Li; You-Sheng Li; Xiao-Ming Wang; Jie-Shou Li
Journal:  World J Gastroenterol       Date:  2004-05-15       Impact factor: 5.742

4.  Extracorporeal Hypothermic Perfusion Device for Intestinal Graft Preservation to Decrease Ischemic Injury During Transportation.

Authors:  Armando Salim Muñoz-Abraham; Roger Patrón-Lozano; Raja R Narayan; Sami S Judeeba; Abedalrazaq Alkukhun; Tariq I Alfadda; Joseph T Belter; David C Mulligan; Raffaella Morotti; Joseph P Zinter; John P Geibel; Manuel I Rodríguez-Dávalos
Journal:  J Gastrointest Surg       Date:  2016-02       Impact factor: 3.452

5.  Pancreatic transplantation at the University of Pittsburgh.

Authors:  Ngoc L Thai; Kareem Abu-Elmagd; Akhar Khan; Geoffrey Bond; Amit Basu; Kusum Tom; George Mazariegos; Rakesh Sindhi; Jorge Reyes; Henkie P Tan; Amadeo Marcos; Thomas E Starzl; Ron Shapiro
Journal:  Clin Transpl       Date:  2004

6.  Guidelines for the assessment and acceptance of potential brain-dead organ donors.

Authors:  Glauco Adrieno Westphal; Valter Duro Garcia; Rafael Lisboa de Souza; Cristiano Augusto Franke; Kalinca Daberkow Vieira; Viviane Renata Zaclikevis Birckholz; Miriam Cristine Machado; Eliana Régia Barbosa de Almeida; Fernando Osni Machado; Luiz Antônio da Costa Sardinha; Raquel Wanzuita; Carlos Eduardo Soares Silvado; Gerson Costa; Vera Braatz; Milton Caldeira Filho; Rodrigo Furtado; Luana Alves Tannous; André Gustavo Neves de Albuquerque; Edson Abdala
Journal:  Rev Bras Ter Intensiva       Date:  2016-09

Review 7.  [Technique of liver procurement in postmortem donation].

Authors:  A A Schnitzbauer; W O Bechstein
Journal:  Chirurg       Date:  2013-05       Impact factor: 0.955

8.  Celsior versus University of Wisconsin preserving solutions for liver transplantation: postreperfusion syndrome and outcome of a 5-year prospective randomized controlled study.

Authors:  Francisco A García-Gil; María T Serrano; Lorena Fuentes-Broto; Juan Arenas; José J García; Antonio Güemes; Vanesa Bernal; Ana Campillo; Carlos Sostres; Juan J Araiz; Pablo Royo; Miguel A Simón
Journal:  World J Surg       Date:  2011-07       Impact factor: 3.352

9.  Clinical intestinal transplantation: a decade of experience at a single center.

Authors:  K Abu-Elmagd; J Reyes; G Bond; G Mazariegos; T Wu; N Murase; R Sindhi; D Martin; J Colangelo; M Zak; D Janson; M Ezzelarab; I Dvorchik; M Parizhskaya; M Deutsch; A Demetris; J Fung; T E Starzl
Journal:  Ann Surg       Date:  2001-09       Impact factor: 12.969

10.  Multivisceral transplantation: expanding indications and improving outcomes.

Authors:  Richard S Mangus; A Joseph Tector; Chandrashekhar A Kubal; Jonathan A Fridell; Rodrigo M Vianna
Journal:  J Gastrointest Surg       Date:  2012-10-16       Impact factor: 3.452

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.