AIM: As the conventional combined liver-small bowel transplantation is complicated with many postoperative complications, the aim of this study was to describe a modified technique for the combined liver-small bowel transplantation with preservation of the duodenum, partial head of pancreas and hepatic biliary system in pigs. METHODS: Composite liver/small bowel allotransplantations were undertaken in 30 long-white pigs. The graft included liver, about 3 to 4 m proximal jejunum, duodenum and partial pancreatic head. Vessels reconstructions included subhepatic vena cava-vena cava anastomosis, aorta-aorta anastomosis and portal-splenic vein anastomosis. RESULTS: Without immunosuppressive treatment, the median survival time of the animals was 6 days (2 to 12 days), and about 76.9 % (20/26) of the animals survived for more than 4 days after operation. CONCLUSION: The modified technique is feasible and safe for the composite liver/small bowel transplantation with duodenum and pancreas preserved in pigs. And also this technique can simplify the operation and decrease possible postoperative complications.
AIM: As the conventional combined liver-small bowel transplantation is complicated with many postoperative complications, the aim of this study was to describe a modified technique for the combined liver-small bowel transplantation with preservation of the duodenum, partial head of pancreas and hepatic biliary system in pigs. METHODS: Composite liver/small bowel allotransplantations were undertaken in 30 long-white pigs. The graft included liver, about 3 to 4 m proximal jejunum, duodenum and partial pancreatic head. Vessels reconstructions included subhepatic vena cava-vena cava anastomosis, aorta-aorta anastomosis and portal-splenic vein anastomosis. RESULTS: Without immunosuppressive treatment, the median survival time of the animals was 6 days (2 to 12 days), and about 76.9 % (20/26) of the animals survived for more than 4 days after operation. CONCLUSION: The modified technique is feasible and safe for the composite liver/small bowel transplantation with duodenum and pancreas preserved in pigs. And also this technique can simplify the operation and decrease possible postoperative complications.
Authors: K Abu-Elmagd; J Fung; J Bueno; D Martin; J R Madariaga; G Mazariegos; G Bond; E Molmenti; R J Corry; T E Starzl; J Reyes Journal: Ann Surg Date: 2000-11 Impact factor: 12.969
Authors: J de Ville de Goyet; A Mitchell; A D Mayer; S V Beath; P J McKiernan; D A Kelly; D Mirza; J A Buckles Journal: Transplantation Date: 2000-02-27 Impact factor: 4.939
Authors: O Goulet; D Jan; S Sarnacki; N Brousse; V Colomb; R Salomon; B Cuenod; H Piloquet; C Ricour; Y Revillon Journal: Transplant Proc Date: 1996-10 Impact factor: 1.066
Authors: T E Starzl; T R Hakala; B W Shaw; R L Hardesty; T J Rosenthal; B P Griffith; S Iwatsuki; H T Bahnson Journal: Surg Gynecol Obstet Date: 1984-03
Authors: J Reyes; J Bueno; S Kocoshis; M Green; K Abu-Elmagd; H Furukawa; E M Barksdale; S Strom; J J Fung; S Todo; W Irish; T E Starzl Journal: J Pediatr Surg Date: 1998-02 Impact factor: 2.545