Literature DB >> 11055034

Should local research ethics committees monitor research they have approved?

E Pickworth1.   

Abstract

The function of local research ethics committees is to consider the ethics of research proposals using human participants. After approval has been given, there is no comprehensive system in place to monitor research and ensure that recommendations are carried out. Some suggest that research ethics committees are ideally placed to fulfil this function by carrying out random monitoring of research they have reviewed. The health service guideline creating local research ethics committees is under review. This paper suggests that increasing the monitoring role of ethics committees in the present climate would be inappropriate. This is due to the large workload of the committees, their voluntary nature and the change a monitoring role might cause to the relationship between researcher and ethics committee, which might herald an increasing recourse to judicial review. A radical overhaul of the system would be necessary in order for ethics committees adequately to fulfil a monitoring function.

Entities:  

Keywords:  Biomedical and Behavioral Research

Mesh:

Year:  2000        PMID: 11055034      PMCID: PMC1733278          DOI: 10.1136/jme.26.5.330

Source DB:  PubMed          Journal:  J Med Ethics        ISSN: 0306-6800            Impact factor:   2.903


  8 in total

1.  Fees and research ethics committees.

Authors:  Emma Pickworth; Margaret Brazier
Journal:  Bull Med Ethics       Date:  1999-10

2.  Deciding when to withhold or withdraw life-sustaining treatment for children.

Authors:  Priscilla Alderson; Richard Nicholson
Journal:  Bull Med Ethics       Date:  1997-04

3.  The need for a national body for research misconduct. Nothing less will reassure the public.

Authors:  R Smith
Journal:  BMJ       Date:  1998-06-06

4.  Short course of zidovudine cuts transmission of HIV.

Authors:  T Rutter
Journal:  BMJ       Date:  1998-02-28

5.  Local Research Ethics Committees can audit ethical standards in research.

Authors:  J Berry
Journal:  J Med Ethics       Date:  1997-12       Impact factor: 2.903

6.  Monitoring approved research protocols--a question of balance. National Health and Medical Research Council.

Authors:  S Linden-Laufer
Journal:  Med Law       Date:  1997

7.  Misconduct in research: editors respond.

Authors:  R Smith
Journal:  BMJ       Date:  1997-07-26

8.  Review by a local medical research ethics committee of the conduct of approved research projects, by examination of patients' case notes, consent forms, and research records and by interview.

Authors:  T Smith; E J Moore; H Tunstall-Pedoe
Journal:  BMJ       Date:  1997-05-31
  8 in total
  4 in total

Review 1.  Ethics in exercise science research.

Authors:  Roy J Shephard
Journal:  Sports Med       Date:  2002       Impact factor: 11.136

2.  Research site monitoring for compliance with ethics regulatory standards: review of experience from Uganda.

Authors:  Joseph Ochieng; Julius Ecuru; Frederick Nakwagala; Paul Kutyabami
Journal:  BMC Med Ethics       Date:  2013-06-05       Impact factor: 2.652

3.  Are institutional review boards prepared for active continuing review?

Authors:  Yashashri C Shetty; Kshitij S Jadhav; Aafreen A Saiyed; Akshay U Desai
Journal:  Perspect Clin Res       Date:  2014-01

4.  Monitoring of approved studies: A difficult tightrope walk by Ethics Committees.

Authors:  Sanish Davis
Journal:  Perspect Clin Res       Date:  2018 Apr-Jun
  4 in total

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