Literature DB >> 10974383

The surgical treatment of metastatic disease of the spine.

N C Hatrick1, J D Lucas, A R Timothy, M A Smith.   

Abstract

BACKGROUND AND
PURPOSE: The spine is the commonest site for skeletal metastases. The majority of patients with spinal metastases can be managed conservatively, at least initially, but a significant number will develop complications, either neurological or mechanical, requiring surgical intervention. This paper emphasizes the need for a spinal surgeon to be involved early in the care of these patients.
MATERIALS AND METHODS: Forty-two patients undergoing surgery for metastatic disease of the spine between January 1995 and June 1997 were reviewed. Thirty-five of the patients had 'instability' pain secondary to pathological vertebral fracture, 25 of whom also had radicular pain secondary to nerve root compression. Six patients had radicular pain but no symptoms of instability. Two of these patients had symptoms of spinal claudication and one further patient had symptoms of spinal claudication alone. Forty of the patients had evidence of thecal compression on magnetic resonance imaging scans and 29 had neurological signs. According to the grading of Frankel (Paraplegia 7 (1969) 179), 14 had a major neurological deficit and 15 had a minor neurological deficit. All patients underwent decompression of the cord or nerve roots and spinal stabilization, 25 via a posterior approach, 15 via an anterior approach and two combined.
RESULTS: Post-operatively pain improved in 38 of the 42 patients (90%), the neurological deficit in 20 of the 29 patients with a deficit (69%) and the ambulatory ability in 25 of the 32 patients (78%) with very restricted mobility.
CONCLUSIONS: Identification of the cause of a patient's symptoms allows appropriate surgical intervention with favourable results.

Entities:  

Mesh:

Year:  2000        PMID: 10974383     DOI: 10.1016/s0167-8140(00)00199-7

Source DB:  PubMed          Journal:  Radiother Oncol        ISSN: 0167-8140            Impact factor:   6.280


  30 in total

1.  En bloc spondylectomy reconstructions in a biomechanical in-vitro study.

Authors:  A C Disch; K D Schaser; I Melcher; A Luzzati; F Feraboli; W Schmoelz
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Review 2.  Review of metastatic spine tumour classification and indications for surgery: the consensus statement of the Global Spine Tumour Study Group.

Authors:  David Choi; A Crockard; C Bunger; J Harms; N Kawahara; C Mazel; R Melcher; K Tomita
Journal:  Eur Spine J       Date:  2009-12-29       Impact factor: 3.134

3.  Surgery improves pain, function and quality of life in patients with spinal metastases: a prospective study on 118 patients.

Authors:  Gerald M Y Quan; Jean-Marc Vital; Nicholas Aurouer; Ibrahim Obeid; Jean Palussière; Abou Diallo; Vincent Pointillart
Journal:  Eur Spine J       Date:  2011-06-26       Impact factor: 3.134

4.  Results of posterior surgery with intraoperative radiotherapy for spinal metastases.

Authors:  Taku Saito; Taiji Kondo; Takahiro Hozumi; Katsuyuki Karasawa; Atsushi Seichi; Kozo Nakamura
Journal:  Eur Spine J       Date:  2005-08-13       Impact factor: 3.134

5.  Rapid magnetic resonance imaging for diagnosing cancer-related low back pain.

Authors:  William Hollingworth; Darryl T Gray; Brook I Martin; Sean D Sullivan; Richard A Deyo; Jeffrey G Jarvik
Journal:  J Gen Intern Med       Date:  2003-04       Impact factor: 5.128

6.  Surgical treatment strategies and outcome in patients with breast cancer metastatic to the spine: a review of 87 patients.

Authors:  Joseph A Shehadi; Daniel M Sciubba; Ian Suk; Dima Suki; Marcos V C Maldaun; Ian E McCutcheon; Remi Nader; Richard Theriault; Laurence D Rhines; Ziya L Gokaslan
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7.  Metastatic non-Hodgkin lymphoma presenting as low back pain and radiculopathy: a case report.

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8.  [Surgical management of vertebral column metastatic disease].

Authors:  K-D Schaser; I Melcher; T Mittlmeier; A Schulz; J H Seemann; N P Haas; A C Disch
Journal:  Unfallchirurg       Date:  2007-02       Impact factor: 1.000

9.  Positive and negative prognostic variables for patients undergoing spine surgery for metastatic breast disease.

Authors:  Daniel M Sciubba; Ziya L Gokaslan; Ian Suk; Dima Suki; Marcos V C Maldaun; Ian E McCutcheon; Remi Nader; Richard Theriault; Laurence D Rhines; Joseph A Shehadi
Journal:  Eur Spine J       Date:  2007-05-08       Impact factor: 3.134

10.  Irreversible Electroporation in the Epidural Space of the Porcine Spine: Effects on Adjacent Structures.

Authors:  Alda L Tam; Tomas A Figueira; Mihai Gagea; Joe E Ensor; Katherine Dixon; Amanda McWatters; Sanjay Gupta; David T Fuentes
Journal:  Radiology       Date:  2016-06-07       Impact factor: 11.105

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