Literature DB >> 23449990

Metastatic non-Hodgkin lymphoma presenting as low back pain and radiculopathy: a case report.

Inger K Roug1, Larry B McCartney.   

Abstract

OBJECTIVE: The purpose of this case report is to describe a case of metastatic non-Hodgkin lymphoma in the lumbar spine presenting as lumbar radiculopathy. CLINICAL FEATURES: A 46-year-old man sought care from his doctor of chiropractic for low back pain and right leg radiculopathy. The patient was referred for a magnetic resonance imaging (MRI) scan to evaluate for a suspected disk herniation. The MRI scan revealed 2 lumbar pathologic compression fractures with cauda equina compression, and MRI short tau inversion recovery (STIR) sagittal image of the lumbar spine showed high signal in T12 and S2. INTERVENTION AND OUTCOME: The patient was referred for an immediate consultation with his medical physician with the preliminary diagnosis of metastatic bone lesions or primary bone lesions of unknown etiology. The patient underwent bone biopsy, computed tomography, and positron emission tomography scanning and was diagnosed with small cell non-Hodgkin lymphoma with osseous metastasis. The patient underwent chemo- and radiation therapy, and the lymphoma is now in remission 18 months later.
CONCLUSION: This case describes the presentation of metastatic non-Hodgkin lymphoma as a possible contributing cause in a patient presenting with lumbar radiculopathy, a common musculoskeletal condition. As well, this case highlights the importance of STIR sequences as part of a routine lumbar spine MRI examination. Without the STIR sequences, the additional deposits in T12 and S1 would not have been readily appreciated. Although metastatic non-Hodgkin lymphoma of the spine is rare, it should be remembered in the differential diagnoses.

Entities:  

Keywords:  Chiropractic; Magnetic resonance imaging; Metastasis; Non-Hodgkin lymphoma; Radiculopathy; Spine

Year:  2012        PMID: 23449990      PMCID: PMC3437349          DOI: 10.1016/j.jcm.2012.05.008

Source DB:  PubMed          Journal:  J Chiropr Med        ISSN: 1556-3707


  19 in total

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Authors:  D Schiff; B P O'Neill; V J Suman
Journal:  Neurology       Date:  1997-08       Impact factor: 9.910

2.  Occupation and the risk of non-Hodgkin lymphoma.

Authors:  Paolo Boffetta; Frank de Vocht
Journal:  Cancer Epidemiol Biomarkers Prev       Date:  2007-03       Impact factor: 4.254

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4.  Primary non-Hodgkin's lymphoma in multiple vertebrae presenting as a lumbar radicular syndrome: A case report.

Authors:  S C M Ebus; H J J A Bernsen; G J Norel Van; R Donk
Journal:  Spine (Phila Pa 1976)       Date:  2002-05-15       Impact factor: 3.468

5.  Malignant lymphoma of bone.

Authors:  Hans Roland Dürr; Peter Ernst Müller; Erhard Hiller; Markus Maier; Andrea Baur; Volkmar Jansson; Hans Jürgen Refior
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6.  Primary Lumbo-sacral Spinal Epidural Non-Hodgkin's Lymphoma: A Case Report and Review of Literature.

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7.  [Malignant lymphomas with first manifestation in the spine as a rare differential diagnosis of lumbar intervertebral disk syndrome].

Authors:  F J Prestar
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Review 8.  Spinal cord compression in patients with advanced metastatic cancer: "all I care about is walking and living my life".

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Review 9.  Primary non-Hodgkin's lymphoma presenting as radicular syndrome: report of two cases.

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Authors:  J W Reggars; S D French
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2.  The etiologies of low back pain in patients with lumbar disk herniation.

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