Literature DB >> 1096810

Treatment of anaerobic infections with metronidazole.

F P Tally, V L Sutter, S M Finegold.   

Abstract

The results of treatment of 10 patients with anaerobic infections with metronidazole are presented. Six patients were cured, three showed initial good response but circumstances required a change to another drug, and one patient did not respond. The unique spectrum of the drug, its pharmacology, and limitations are discussed. The results indicate that further clinical trials to determine the efficacy of metronidazole in the treatment of anerobic infections are indicated.

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Year:  1975        PMID： 1096810      PMCID： PMC429201          DOI： 10.1128/AAC.7.5.672

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  19 in total

1.  TREATMENT OF VINCENT'S STOMATITIS WITH METRONIDAZOLE.

Authors:  A H DAVIES; J A MCFADZEAN; S SQUIRES
Journal:  Br Med J       Date:  1964-05-02

2.  [The activity of 1-(2-hydroxyethyl)-2-methyl-5-nitroimidazole (R. P. 8823) against experimental Trichomonas vaginalis infections].

Authors:  C COSAR; L JULOU
Journal:  Ann Inst Pasteur (Paris)       Date:  1959-02

3.  Absorption and excretion of metronidazole. I. Serum concentration and urinary excretion after oral administration.

Authors:  P O KANE; J A McFADZEAN; S SQUIRES; A J KING; C S NICOL
Journal:  Br J Vener Dis       Date:  1961-12

4.  Clindamycin-associated colitis.

Authors:  L E Cohen; C J McNeill; R F Wells
Journal:  JAMA       Date:  1973-03-19       Impact factor: 56.272

5.  Resistance of some species of Clostridium to clindamycin.

Authors:  T D Wilkins; T Thiel
Journal:  Antimicrob Agents Chemother       Date:  1973-01       Impact factor: 5.191

6.  Diagnostic features of clindamycin-associated pseudomembranous colitis.

Authors:  F J Tedesco; R J Stanley; D H Alpers
Journal:  N Engl J Med       Date:  1974-04-11       Impact factor: 91.245

7.  In vitro antimicrobial susceptibility of anaerobic bacteria isolated from clinical specimens.

Authors:  W J Martin; M Gardner; J A Washington
Journal:  Antimicrob Agents Chemother       Date:  1972-02       Impact factor: 5.191

8.  Bactericidal activity of metronidazole against Bacteroides fragilis.

Authors:  J P Whelan; J H Hale
Journal:  J Clin Pathol       Date:  1973-06       Impact factor: 3.411

9.  Metronidazole versus anaerobes. In vitro data and initial clinical observations.

Authors:  F P Tally; V L Sutter; S M Finegold
Journal:  Calif Med       Date:  1972-12

10.  Effects of l-(2-nitro-l-imidazolyl)-3-methoxy-2-propanol and 2-methyl-5-nitroimidazole-l-ethanol against anaerobic and aerobic bacteria and protozoa.

Authors:  H N Prince; E Grunberg; E Titsworth; W F DeLorenzo
Journal:  Appl Microbiol       Date:  1969-11
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  30 in total

1.  Antimicrobial activity of metronidazole in anaerobic bacteria.

Authors:  F P Tally; B R Goldin; N Sullivan; J Johnston; S L Gorbach
Journal:  Antimicrob Agents Chemother       Date:  1978-03       Impact factor: 5.191

2.  Susceptibility to beta-lactam antibiotics and production of beta-lactamase in Bacteroides fragilis.

Authors:  B Olsson; K Dornbusch; C E Nord
Journal:  Med Microbiol Immunol       Date:  1977-10-07       Impact factor: 3.402

3.  Effects of antimicrobial therapy on faecal bulking.

Authors:  A V Kurpad; P S Shetty
Journal:  Gut       Date:  1986-01       Impact factor: 23.059

4.  Artifactual depression of serum glutamic oxaloacetic transaminase by metronidazole.

Authors:  J P Rissing; C Newman; W L Moore
Journal:  Antimicrob Agents Chemother       Date:  1978-10       Impact factor: 5.191

5.  Access of metronidazole into the chronically inflamed middle ear with reference to anaerobic bacterial infections.

Authors:  L Jokipii; P Karma; A M Jokipii
Journal:  Arch Otorhinolaryngol       Date:  1978-06-27

6.  Susceptibility of anaerobic bacteria to metronidazole, ornidazole, and tinidazole and routine susceptibility testing by standardized methods.

Authors:  J Wust
Journal:  Antimicrob Agents Chemother       Date:  1977-04       Impact factor: 5.191

7.  Effect of antibiotics on the prevention of experimental Bacteroides fragilis endocarditis.

Authors:  P L Goldman; D T Durack; R G Petersdorf
Journal:  Antimicrob Agents Chemother       Date:  1978-11       Impact factor: 5.191

8.  Comparison of the activity of ionophores with other antibacterial agents against anaerobes.

Authors:  K Watanabe; J Watanabe; S Kuramitsu; H B Maruyama
Journal:  Antimicrob Agents Chemother       Date:  1981-04       Impact factor: 5.191

9.  The penetration of metronidazole into synovial fluid.

Authors:  M A Sattar; M G Sankey; M I Cawley; C M Kaye; J E Holt
Journal:  Postgrad Med J       Date:  1982-01       Impact factor: 2.401

10.  In vitro activity of josamycin and rosamicin against Bacteroides fragilis compared with clindamycin, erythromycin, and metronidazole.

Authors:  J Santoro; D Kaye; M E Levison
Journal:  Antimicrob Agents Chemother       Date:  1976-07       Impact factor: 5.191
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