| Literature DB >> 7247375 |
K Watanabe, J Watanabe, S Kuramitsu, H B Maruyama.
Abstract
Representative polyethers of each group in Westley's classification and related ionophore antibiotics were examined for in vitro activity against 25 anaerobic strains. Lasalocid (X-537A) and nigericin were found to have activity comparable in potency to some leading antianaerobe antibiotics, newer cephalosporins and nitroimidazoles, with a different spectrum as revealed by a spectral comparison. A strict relationship between their antianaerobe activity and either their structural features or cation transporting properties was not apparent.Entities:
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Year: 1981 PMID: 7247375 PMCID: PMC181469 DOI: 10.1128/AAC.19.4.519
Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN: 0066-4804 Impact factor: 5.191