Literature DB >> 984752

In vitro activity of josamycin and rosamicin against Bacteroides fragilis compared with clindamycin, erythromycin, and metronidazole.

J Santoro, D Kaye, M E Levison.   

Abstract

The inhibitory and bactericidal activities of josamycin and rosamicin against 29 clinical isolates of Bacteroides fragilis were compared with those of clindamycin, erythromycin, and metronidazole by a broth dilution technique. Josamycin and rosamicin had similar inhibitory activity to metronidazole and clindamycin. Rosamicin had similar bactericidal activity to clindamycin but was less bactericidal than metronidazole (the most bactericidal agent tested). Josamycin was slightly more bactericidal than erythromycin (the least bactericidal agent tested), but less so than rosamicin and clindamycin.

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Year:  1976        PMID: 984752      PMCID: PMC429713          DOI: 10.1128/AAC.10.1.188

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN: 0066-4804            Impact factor:   5.191


  8 in total

1.  An evaluation of the carbon dioxide component in the GasPak anaerobic system.

Authors:  I R Ferguson; K D Phillips; P V Tearle
Journal:  J Appl Bacteriol       Date:  1975-10

2.  In vitro susceptibility studies with josamycin and erythromycin.

Authors:  L J Strausbaugh; J A Dilworth; J M Gwaltney; M A Sande
Journal:  Antimicrob Agents Chemother       Date:  1976-03       Impact factor: 5.191

3.  Rosamicin: in vitro activity against anaerobes and comparison with erythromycin.

Authors:  V L Sutter; S M Finegold
Journal:  Antimicrob Agents Chemother       Date:  1976-02       Impact factor: 5.191

4.  Bactericidal activity of five antimicrobial agents against Bacteroides fragilis.

Authors:  L J Nastro; S M Finegold
Journal:  J Infect Dis       Date:  1972-07       Impact factor: 5.226

5.  Treatment of anaerobic infections with metronidazole.

Authors:  F P Tally; V L Sutter; S M Finegold
Journal:  Antimicrob Agents Chemother       Date:  1975-05       Impact factor: 5.191

6.  Antibiotic susceptibility of the subspecies of Bacteroides fragilis.

Authors:  D J Blazevic
Journal:  Antimicrob Agents Chemother       Date:  1976-03       Impact factor: 5.191

7.  Metronidazole versus anaerobes. In vitro data and initial clinical observations.

Authors:  F P Tally; V L Sutter; S M Finegold
Journal:  Calif Med       Date:  1972-12

8.  Treatment of anaerobic bacterial infections with clindamycin-2-phosphate.

Authors:  M E Levison; J L Bran; K Ries
Journal:  Antimicrob Agents Chemother       Date:  1974-03       Impact factor: 5.191

  8 in total
  5 in total

1.  In vitro activity of rosamicin and erythromycin against a group of nonfermenting gram-negative bacilli.

Authors:  J R DiPersio; T L Krafczyk
Journal:  Antimicrob Agents Chemother       Date:  1978-08       Impact factor: 5.191

2.  In vitro susceptibility of 30 strains of Chlamydia trachomatis to rosamicin.

Authors:  T F Smith; H E Washton
Journal:  Antimicrob Agents Chemother       Date:  1978-09       Impact factor: 5.191

3.  Activity of semisynthetic penicillins and synergism with mecillinam against Bacteroides species.

Authors:  I Trestman; D Kaye; M E Levison
Journal:  Antimicrob Agents Chemother       Date:  1979-09       Impact factor: 5.191

Review 4.  Metronidazole in anaerobic infections: a review of its activity, pharmacokinetics and therapeutic use.

Authors:  R N Brogden; R C Heel; T M Speight; G S Avery
Journal:  Drugs       Date:  1978-11       Impact factor: 9.546

5.  In vitro susceptibility of Ureaplasma urealyticum to rosaramicin.

Authors:  T F Smith
Journal:  Antimicrob Agents Chemother       Date:  1979-07       Impact factor: 5.191

  5 in total

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