Literature DB >> 10890607

Observations of withdrawal of life-sustaining treatment from patients who became non-heart-beating organ donors.

M A DeVita1, J V Snyder, R M Arnold, L A Siminoff.   

Abstract

OBJECTIVE: Non-heart-beating organ donation for transplantation is increasing despite the concern whether all the donors are dead. This concern is based on the adequacy of documentation of death and the appropriate duration that circulation and respiration should be absent before death certification. No studies have examined the documentation and deaths of patients who became non-heart-beating organ donors.
DESIGN: Retrospective study of observational data. PATIENTS: All non-brain-dead patients who became non-heart-beating organ donors at the University of Pittsburgh Medical Center from January 1, 1993, to June 30, 1998, were identified. Records for 15 of 16 patients were available for review.
MEASUREMENTS AND MAIN RESULTS: Adequacy of documentation, extubation time, onset of severe hypotension, duration of absent circulation before death was certified, and the time of incision for organ procurement were ascertained. Twelve of 15 records had all required clinical documentation. The mean age of patients was 46.5 +/- 5.7 yrs. All 15 patients were extubated before death and had femoral arterial catheters; one had a biventricular assist device discontinued. The time of hypotension and pulselessness was not documented for one and three patients, respectively. All 12 patients with documentation had > or =2 mins of absent circulation. Time from certification to incision for procurement was 1.1 +/- 2.3 mins.
CONCLUSIONS: In a small study of non-heart-beating organ donation, circulation never resumed after >1 min of absent circulation, suggesting that 2 mins of absent circulation is sufficient to certify death. Three of 15 patients had inadequate documentation. Gaps and inconsistencies in documentation may raise concern about the potential for abuse.

Entities:  

Keywords:  Death and Euthanasia; Empirical Approach; Health Care and Public Health; University of Pittsburgh Medical Center

Mesh:

Year:  2000        PMID: 10890607     DOI: 10.1097/00003246-200006000-00002

Source DB:  PubMed          Journal:  Crit Care Med        ISSN: 0090-3493            Impact factor:   7.598


  9 in total

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2.  Neurointensivists' opinions about death by neurological criteria and organ donation.

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5.  Non-heart beating organ donation: old procurement strategy--new ethical problems.

Authors:  M D D Bell
Journal:  J Med Ethics       Date:  2003-06       Impact factor: 2.903

6.  A Comparison of Request Process and Outcomes in Donation After Cardiac Death and Donation After Brain Death: Results From a National Study.

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7.  In defense of the reverence of all life: Heideggerean dissolution of the ethical challenges of organ donation after circulatory determination of death.

Authors:  D J Isch
Journal:  Med Health Care Philos       Date:  2007-05-02

8.  The ethics of donation and transplantation: are definitions of death being distorted for organ transplantation?

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9.  Pro/con ethics debate: is nonheart-beating organ donation ethically acceptable?

Authors:  Leslie Whetstine; Kerry Bowman; Laura Hawryluck
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  9 in total

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