Literature DB >> 10878701

QT interval in twins.

N Carter1, H Snieder, S Jeffery, R Saumarez, C Varma, L Antoniades, T D Spector.   

Abstract

QT interval has been determined in 103 monozygotic (MZ) and 198 dizygotic (DZ) female twins. Mean values of corrected QT (QTc) were almost identical for both groups at 413 ms (MZ) and 412 ms (DZ). There was a significant age and environmental effect on QT interval. Heritability explained about 25% of the variation in QT. Further research will show whether any of the genes known to cause Long QT syndrome have any effect on QT interval at the sub-clinical level. Journal of Human Hypertension (2000) 14, 389-390

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Year:  2000        PMID： 10878701     DOI： 10.1038/sj.jhh.1001026

Source DB:  PubMed          Journal:  J Hum Hypertens        ISSN： 0950-9240            Impact factor:   3.012


  14 in total

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2.  Genetics of cardiac repolarization.

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Journal:  Nat Genet       Date:  2009-04       Impact factor: 38.330

3.  Analysis of genetic and non-genetic factors that affect the QTc interval in a Mongolian population: the GENDISCAN study.

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4.  Quantifying the origins of population variability in cardiac electrical activity through sensitivity analysis of the electrocardiogram.

Authors:  Arash Sadrieh; Stefan A Mann; Rajesh N Subbiah; Luke Domanski; John A Taylor; Jamie I Vandenberg; Adam P Hill
Journal:  J Physiol       Date:  2013-04-03       Impact factor: 5.182

5.  Association between QTc of patients with schizophrenia and five genetic polymorphisms of GSTZ1 and XRCC1.

Authors:  Mostafa Saadat
Journal:  Heart Asia       Date:  2014-01-30

Review 6.  The genetics of sudden cardiac death.

Authors:  Dan E Arking; Nona Sotoodehnia
Journal:  Annu Rev Genomics Hum Genet       Date:  2012-06-11       Impact factor: 8.929

7.  Genetic influences on resting electrocardiographic variables in older women: a twin study.

Authors:  Sara Mutikainen; Alfredo Ortega-Alonso; Markku Alén; Jaakko Kaprio; Jouko Karjalainen; Taina Rantanen; Urho M Kujala
Journal:  Ann Noninvasive Electrocardiol       Date:  2009-01       Impact factor: 1.468

8.  Genetic polymorphism of glutathione S-transferase T1 (GSTT1) and QT-interval in schizophrenia patients.

Authors:  Aminollah Bahaoddini; Hassan Farrashbandi; Mostafa Saadat
Journal:  J Mol Neurosci       Date:  2009-01-16       Impact factor: 3.444

9.  Associations between genetic variants in the NOS1AP (CAPON) gene and cardiac repolarization in the old order Amish.

Authors:  Wendy Post; Haiqing Shen; Coleen Damcott; Dan E Arking; W H Linda Kao; Paul A Sack; Kathleen A Ryan; Aravinda Chakravarti; Braxton D Mitchell; Alan R Shuldiner
Journal:  Hum Hered       Date:  2007-06-12       Impact factor: 0.444

10.  Common genetic variation near the phospholamban gene is associated with cardiac repolarisation: meta-analysis of three genome-wide association studies.

Authors:  Ilja M Nolte; Chris Wallace; Stephen J Newhouse; Daryl Waggott; Jingyuan Fu; Nicole Soranzo; Rhian Gwilliam; Panos Deloukas; Irina Savelieva; Dongling Zheng; Chrysoula Dalageorgou; Martin Farrall; Nilesh J Samani; John Connell; Morris Brown; Anna Dominiczak; Mark Lathrop; Eleftheria Zeggini; Louise V Wain; Christopher Newton-Cheh; Mark Eijgelsheim; Kenneth Rice; Paul I W de Bakker; Arne Pfeufer; Serena Sanna; Dan E Arking; Folkert W Asselbergs; Tim D Spector; Nicholas D Carter; Steve Jeffery; Martin Tobin; Mark Caulfield; Harold Snieder; Andrew D Paterson; Patricia B Munroe; Yalda Jamshidi
Journal:  PLoS One       Date:  2009-07-09       Impact factor: 3.240
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