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Literature DB >> 10858363

Cloning and sequence of the gene encoding a novel cefotaxime-hydrolyzing beta-lactamase (CTX-M-9) from Escherichia coli in Spain.

M Sabaté¹, R Tarragó, F Navarro, E Miró, C Vergés, J Barbé, G Prats.

Abstract

A new CTX-M-type beta-lactamase (CTX-M-9) has been cloned from a clinical cefotaxime-resistant Escherichia coli strain. Despite the close identity that exists between the CTX-M-9 and Toho-2 beta-lactamases (88%), the 35 amino acids located between residues Ala-185 and Ala-219 are totally different in both enzymes. Outside of this region there are only six amino acids substitutions between both proteins.

Entities: Chemical Disease Species

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Year: 2000 PMID： 10858363 PMCID： PMC89994 DOI： 10.1128/AAC.44.7.1970-1973.2000

Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN： 0066-4804 Impact factor: 5.191

20 in total

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4. Construction of vectors with the p15a replicon, kanamycin resistance, inducible lacZ alpha and pUC18 or pUC19 multiple cloning sites.

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6. Two novel plasmid-mediated cefotaxime-hydrolyzing beta-lactamases (CTX-M-5 and CTX-M-6) from Salmonella typhimurium.

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7. Beta-lactamases: determination of their isoelectric points.

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8. A new plasmidic cefotaximase in a clinical isolate of Escherichia coli.

Authors: A Bauernfeind; H Grimm; S Schweighart
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9. CTX-M-5, a novel cefotaxime-hydrolyzing beta-lactamase from an outbreak of Salmonella typhimurium in Latvia.

Authors: P A Bradford; Y Yang; D Sahm; I Grope; D Gardovska; G Storch
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10. Identification of the Rhodobacter sphaeroides SOS box.

Authors: A R Fernández de Henestrosa; E Rivera; A Tapias; J Barbé
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58 in total

1. Nucleotide sequence and characterization of a novel cefotaxime-hydrolyzing beta-lactamase (CTX-M-10) isolated in Spain.

Authors: A Oliver; J C Pérez-Díaz; T M Coque; F Baquero; R Cantón
Journal: Antimicrob Agents Chemother Date: 2001-02 Impact factor: 5.191

2. What's New in beta-lactamases?

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4. Characterization of a chromosomally encoded extended-spectrum class A beta-lactamase from Kluyvera cryocrescens.

Authors: J W Decousser; L Poirel; P Nordmann
Journal: Antimicrob Agents Chemother Date: 2001-12 Impact factor: 5.191

5. Countrywide spread of CTX-M-3 extended-spectrum beta-lactamase-producing microorganisms of the family Enterobacteriaceae in Poland.

Authors: Anna Baraniak; Janusz Fiett; Agnieszka Sulikowska; Waleria Hryniewicz; Marek Gniadkowski
Journal: Antimicrob Agents Chemother Date: 2002-01 Impact factor: 5.191

6. Plasmidic extended-spectrum beta-lactamases in Vibrio cholerae O1 El Tor isolates in Argentina.

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7. Three cefotaximases, CTX-M-9, CTX-M-13, and CTX-M-14, among Enterobacteriaceae in the People's Republic of China.

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Journal: Antimicrob Agents Chemother Date: 2002-03 Impact factor: 5.191

8. Identification of CTX-M-14 extended-spectrum beta-lactamase in clinical isolates of Shigella sonnei, Escherichia coli, and Klebsiella pneumoniae in Korea.

Authors: H Pai; E H Choi; H J Lee; J Y Hong; G A Jacoby
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Review 9. Extended-spectrum beta-lactamases in the 21st century: characterization, epidemiology, and detection of this important resistance threat.

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10. Molecular characterization of a novel plasmid-encoded cefotaximase (CTX-M-12) found in clinical Klebsiella pneumoniae isolates from Kenya.

Authors: S Kariuki; J E Corkill; G Revathi; R Musoke; C A Hart
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