Literature DB >> 9742701

Two novel plasmid-mediated cefotaxime-hydrolyzing beta-lactamases (CTX-M-5 and CTX-M-6) from Salmonella typhimurium.

M Gazouli1, E Tzelepi, A Markogiannakis, N J Legakis, L S Tzouvelekis.   

Abstract

Two novel plasmid-mediated beta-lactamases (CTX-M-5 and CTX-M-6) produced by Salmonella typhimurium clinical strains were characterized. The enzymes exhibited a pI of 8.4, hydrolyzed oxyimino-beta-lactams and were susceptible to mechanism-based beta-lactamase inhibitors. The respective bla genes were cloned and sequenced. The deduced amino acid sequences showed a high degree of homology with those of the previously described plasmid class A CTX-M-type enzymes and appeared related to the chromosomal beta-lactamases of Klebsiella oxytoca.

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Year:  1998        PMID： 9742701     DOI： 10.1111/j.1574-6968.1998.tb13159.x

Source DB:  PubMed          Journal:  FEMS Microbiol Lett        ISSN： 0378-1097            Impact factor:   2.742


  33 in total

1.  Nucleotide sequence and characterization of a novel cefotaxime-hydrolyzing beta-lactamase (CTX-M-10) isolated in Spain.

Authors:  A Oliver; J C Pérez-Díaz; T M Coque; F Baquero; R Cantón
Journal:  Antimicrob Agents Chemother       Date:  2001-02       Impact factor: 5.191

2.  Cloning and sequence of the gene encoding a novel cefotaxime-hydrolyzing beta-lactamase (CTX-M-9) from Escherichia coli in Spain.

Authors:  M Sabaté; R Tarragó; F Navarro; E Miró; C Vergés; J Barbé; G Prats
Journal:  Antimicrob Agents Chemother       Date:  2000-07       Impact factor: 5.191

3.  What's New in beta-lactamases?

Authors:  Patricia A. Bradford
Journal:  Curr Infect Dis Rep       Date:  2001-02       Impact factor: 3.725

4.  First isolation of a CTX-M-3-producing Enterobacter cloacae in France.

Authors:  F Doucet-Populaire; J C Ghnassia; R Bonnet; J Sirot
Journal:  Antimicrob Agents Chemother       Date:  2000-11       Impact factor: 5.191

5.  Salmonella enterica serovar virchow with CTX-M-like beta-lactamase in Spain.

Authors:  E Simarro; F Navarro; J Ruiz; E Miró; J Gómez; B Mirelis
Journal:  J Clin Microbiol       Date:  2000-12       Impact factor: 5.948

6.  Early dissemination of CTX-M-derived enzymes in South America.

Authors:  Marcela Radice; Pablo Power; Jose Di Conza; Gabriel Gutkind
Journal:  Antimicrob Agents Chemother       Date:  2002-02       Impact factor: 5.191

7.  Countrywide spread of CTX-M-3 extended-spectrum beta-lactamase-producing microorganisms of the family Enterobacteriaceae in Poland.

Authors:  Anna Baraniak; Janusz Fiett; Agnieszka Sulikowska; Waleria Hryniewicz; Marek Gniadkowski
Journal:  Antimicrob Agents Chemother       Date:  2002-01       Impact factor: 5.191

8.  Plasmidic extended-spectrum beta-lactamases in Vibrio cholerae O1 El Tor isolates in Argentina.

Authors:  Alejandro Petroni; Alejandra Corso; Roberto Melano; María Luisa Cacace; Ana María Bru; Alicia Rossi; Marcelo Galas
Journal:  Antimicrob Agents Chemother       Date:  2002-05       Impact factor: 5.191

9.  Three cefotaximases, CTX-M-9, CTX-M-13, and CTX-M-14, among Enterobacteriaceae in the People's Republic of China.

Authors:  Aroonwadee Chanawong; Fatima Hannachi M'Zali; John Heritage; Jian-Hui Xiong; Peter Michael Hawkey
Journal:  Antimicrob Agents Chemother       Date:  2002-03       Impact factor: 5.191

Review 10.  Extended-spectrum beta-lactamases in the 21st century: characterization, epidemiology, and detection of this important resistance threat.

Authors:  P A Bradford
Journal:  Clin Microbiol Rev       Date:  2001-10       Impact factor: 26.132
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