Literature DB >> 10597032

Ribozymes--why so many, why so few?

F J Schmidt1.   

Abstract

The RNA world scenario posits the existence of catalytic and genetic networks whose reactions are catalyzed by RNAs. Substantial progress has been made in recent years in the selection of RNA catalysts by SELEX, thus verifying one prediction of the model. However, many selected catalysts are long molecules, leading to a question of whether they could have been synthesized by a primitive replicator. It is proposed that the efficiency of some small ribozymes may have been augmented by other RNAs acting as transactivators.

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Year:  1999        PMID: 10597032

Source DB:  PubMed          Journal:  Mol Cells        ISSN: 1016-8478            Impact factor:   5.034


  4 in total

1.  Ligation activity of fragmented ribozymes in frozen solution: implications for the RNA world.

Authors:  Alexander V Vlassov; Brian H Johnston; Laura F Landweber; Sergei A Kazakov
Journal:  Nucleic Acids Res       Date:  2004-05-25       Impact factor: 16.971

Review 2.  The RNA world on ice: a new scenario for the emergence of RNA information.

Authors:  Alexander V Vlassov; Sergei A Kazakov; Brian H Johnston; Laura F Landweber
Journal:  J Mol Evol       Date:  2005-07-13       Impact factor: 2.395

3.  Frequency of RNA-RNA interaction in a model of the RNA World.

Authors:  John C Striggles; Matthew B Martin; Francis J Schmidt
Journal:  RNA       Date:  2006-03       Impact factor: 4.942

4.  Possible Ancestral Functions of the Genetic and RNA Operational Precodes and the Origin of the Genetic System.

Authors:  Juan A Martínez-Giménez; Rafael Tabares-Seisdedos
Journal:  Orig Life Evol Biosph       Date:  2021-06-07       Impact factor: 1.950

  4 in total

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