| Literature DB >> 10597032 |
Abstract
The RNA world scenario posits the existence of catalytic and genetic networks whose reactions are catalyzed by RNAs. Substantial progress has been made in recent years in the selection of RNA catalysts by SELEX, thus verifying one prediction of the model. However, many selected catalysts are long molecules, leading to a question of whether they could have been synthesized by a primitive replicator. It is proposed that the efficiency of some small ribozymes may have been augmented by other RNAs acting as transactivators.Entities:
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Year: 1999 PMID: 10597032
Source DB: PubMed Journal: Mol Cells ISSN: 1016-8478 Impact factor: 5.034