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Literature DB >> 1056010

Failure of the opiate antagonist naloxone to modify hypnotic analgesia.

Abstract

Hypnotic analgesia in some respects resembles opiate analgesia. We tested the hypothesis that some features of hypnotic analgesia are mediated through neuronal pathways activating specific opiate receptors in brain. The opiate antagonist naloxone had no effect on hypnotic analgesia in three subjects. Thus, the hypothesis was not confirmed.

Entities: Chemical Disease

Mesh：

Substances：
Naloxone

Year: 1975 PMID： 1056010 PMCID： PMC432688 DOI： 10.1073/pnas.72.6.2041

Source DB: PubMed Journal: Proc Natl Acad Sci U S A ISSN： 0027-8424 Impact factor: 11.205

16 in total

1. Sites of morphine induced analgesia in the primate brain: relation to pain pathways.

Authors: A Pert; T Yaksh
Journal: Brain Res Date: 1974-11-08 Impact factor: 3.252

2. Regional distribution of opiate receptor binding in monkey and human brain.

Authors: M J Kuhar; C B Pert; S H Snyder
Journal: Nature Date: 1973-10-26 Impact factor: 49.962

3. [Comparison in the rat between analgesia induced by stimulation of periacqueducal gray matter and morphine analgesia].

Authors: H Akil; D J Mayer; J C Liebeskind
Journal: C R Acad Hebd Seances Acad Sci D Date: 1972-06-26

4. Partial purification of an opiate receptor from mouse brain.

Authors: L I Lowney; K Schulz; P J Lowery; A Goldstein
Journal: Science Date: 1974-02-22 Impact factor: 47.728

5. [Enhancement of nociceptive reactions by naloxone in mice and rats (author's transl)].

Authors: J J Jacob; E C Tremblay; M C Colombel
Journal: Psychopharmacologia Date: 1974-07-11

6. Distribution of stereospecific binding of the potent narcotic analgesic etorphine in the human brain: predominance in the limbic system.

Authors: J M Hiller; J Pearson; E J Simon
Journal: Res Commun Chem Pathol Pharmacol Date: 1973-11

7. Naloxone in heroin dependence.

Authors: M Fink; A Zaks; R Sharoff; A Mora; A Bruner; S Levit; A M Freedman
Journal: Clin Pharmacol Ther Date: 1968 Sep-Oct Impact factor: 6.875

8. Analgesia from electrical stimulation in the brainstem of the rat.

Authors: D J Mayer; T L Wolfle; H Akil; B Carder; J C Liebeskind
Journal: Science Date: 1971-12-24 Impact factor: 47.728

9. Stereospecific binding of the potent narcotic analgesic (3H) Etorphine to rat-brain homogenate.

Authors: E J Simon; J M Hiller; I Edelman
Journal: Proc Natl Acad Sci U S A Date: 1973-07 Impact factor: 11.205

10. Stereospecific and nonspecific interactions of the morphine congener levorphanol in subcellular fractions of mouse brain.

Authors: A Goldstein; L I Lowney; B K Pal
Journal: Proc Natl Acad Sci U S A Date: 1971-08 Impact factor: 11.205

12 in total

Failure of the opiate antagonist naloxone to modify hypnotic analgesia.

1. Sites of morphine induced analgesia in the primate brain: relation to pain pathways.

2. Regional distribution of opiate receptor binding in monkey and human brain.

3. [Comparison in the rat between analgesia induced by stimulation of periacqueducal gray matter and morphine analgesia].

4. Partial purification of an opiate receptor from mouse brain.

5. [Enhancement of nociceptive reactions by naloxone in mice and rats (author's transl)].

6. Distribution of stereospecific binding of the potent narcotic analgesic etorphine in the human brain: predominance in the limbic system.

7. Naloxone in heroin dependence.

8. Analgesia from electrical stimulation in the brainstem of the rat.

9. Stereospecific binding of the potent narcotic analgesic (3H) Etorphine to rat-brain homogenate.

10. Stereospecific and nonspecific interactions of the morphine congener levorphanol in subcellular fractions of mouse brain.

1. The role of behavioral scientists in the teaching of pain and anxiety control.

2. Current and future research in dental sedation and anesthesia.

3. Enhancement of a nociceptive reaction by opioid antagonists in mice.

4. Hypnosis in the treatment of acute pain in the emergency department setting.

5. The effect of hypnotically induced analgesia on flare reaction of the cutaneous histamine prick test.

6. Interactions between personal expectations and naloxone: effects on tolerance to ischemic pain.

7. Hypnotic analgesia in conditions of stress is partially reversed by naloxone.

8. [On the physiology and pharmacology of endorphins (author's transl)].

9. [Psychophysiology of fire walking. II. Pain perception in pyrovasy (fire walking)].

10. Naloxone fails to reverse hypnotic alleviation of chronic pain.