Literature DB >> 4821242

Partial purification of an opiate receptor from mouse brain.

L I Lowney, K Schulz, P J Lowery, A Goldstein.   

Abstract

A proteolipid isolated from a lipid extract of mouse brain demonstrates stereospecific binding properties for levorphanol. It is present only in neuronal tissue and most abundant in the rhombencephalon. One component saturates at a concentration corresponding to maximum pharmacologic effect in vivo. The estimated mass is 60,000 daltons per bound opiate molecule.

Entities:  

Mesh:

Substances:

Year:  1974        PMID: 4821242     DOI: 10.1126/science.183.4126.749

Source DB:  PubMed          Journal:  Science        ISSN: 0036-8075            Impact factor:   47.728


  6 in total

Review 1.  Exploring the neuroimmunopharmacology of opioids: an integrative review of mechanisms of central immune signaling and their implications for opioid analgesia.

Authors:  Mark R Hutchinson; Yehuda Shavit; Peter M Grace; Kenner C Rice; Steven F Maier; Linda R Watkins
Journal:  Pharmacol Rev       Date:  2011-07-13       Impact factor: 25.468

2.  The opiate receptors.

Authors:  E J Simon
Journal:  Neurochem Res       Date:  1976-02       Impact factor: 3.996

3.  5-Hydroxytryptamine binding to butanol extracts from myelin fragments.

Authors:  R Ishitani; A Miyakawa; R Saito; T Iwamoto
Journal:  Experientia       Date:  1977-07-15

4.  Bacteriological studies with morphine-like narcotics: relevance to narcotic actions in mammals?

Authors:  A D Wolfe; J G Olenick; F E Hahn
Journal:  Antimicrob Agents Chemother       Date:  1975-02       Impact factor: 5.191

Review 5.  On the role of sulfolipids in mammalian metabolism.

Authors:  A A Farooqui; L A Horrocks
Journal:  Mol Cell Biochem       Date:  1985-02       Impact factor: 3.396

6.  Failure of the opiate antagonist naloxone to modify hypnotic analgesia.

Authors:  A Goldstein; E R Hilgard
Journal:  Proc Natl Acad Sci U S A       Date:  1975-06       Impact factor: 11.205

  6 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.