Literature DB >> 10428935

Comparative in vitro activities of ciprofloxacin, clinafloxacin, gatifloxacin, levofloxacin, moxifloxacin, and trovafloxacin against Klebsiella pneumoniae, Klebsiella oxytoca, Enterobacter cloacae, and Enterobacter aerogenes clinical isolates with alterations in GyrA and ParC proteins.

S Brisse1, D Milatovic, A C Fluit, J Verhoef, N Martin, S Scheuring, K Köhrer, F J Schmitz.   

Abstract

The in vitro activities of ciprofloxacin, clinafloxacin, gatifloxacin, levofloxacin, moxifloxacin, and trovafloxacin were tested against 72 ciprofloxacin-resistant and 28 ciprofloxacin-susceptible isolates of Klebsiella pneumoniae, Klebsiella oxytoca, Enterobacter cloacae, and Enterobacter aerogenes. Irrespective of the alterations in GyrA and ParC proteins, clinafloxacin exhibited greater activity than all other fluoroquinolones tested against K. pneumoniae and E. aerogenes.

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Year:  1999        PMID： 10428935      PMCID： PMC89413     

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  19 in total

1.  New topoisomerase essential for chromosome segregation in E. coli.

Authors:  J Kato; Y Nishimura; R Imamura; H Niki; S Hiraga; H Suzuki
Journal:  Cell       Date:  1990-10-19       Impact factor: 41.582

2.  Cloning and sequence analysis of gyrA gene of Klebsiella pneumoniae.

Authors:  G P Dimri; H K Das
Journal:  Nucleic Acids Res       Date:  1990-01-11       Impact factor: 16.971

3.  Characterization of grlA, grlB, gyrA, and gyrB mutations in 116 unrelated isolates of Staphylococcus aureus and effects of mutations on ciprofloxacin MIC.

Authors:  F J Schmitz; M E Jones; B Hofmann; B Hansen; S Scheuring; M Lückefahr; A Fluit; J Verhoef; U Hadding; H P Heinz; K Köhrer
Journal:  Antimicrob Agents Chemother       Date:  1998-05       Impact factor: 5.191

4.  Alterations in the GyrA subunit of DNA gyrase and the ParC subunit of topoisomerase IV in quinolone-resistant clinical isolates of Klebsiella pneumoniae.

Authors:  T Deguchi; A Fukuoka; M Yasuda; M Nakano; S Ozeki; E Kanematsu; Y Nishino; S Ishihara; Y Ban; Y Kawada
Journal:  Antimicrob Agents Chemother       Date:  1997-03       Impact factor: 5.191

5.  Quinolone resistance-determining region in the DNA gyrase gyrA gene of Escherichia coli.

Authors:  H Yoshida; M Bogaki; M Nakamura; S Nakamura
Journal:  Antimicrob Agents Chemother       Date:  1990-06       Impact factor: 5.191

6.  Comparison of the antibacterial activities of the quinolones Bay 12-8039, gatifloxacin (AM 1155), trovafloxacin, clinafloxacin, levofloxacin and ciprofloxacin.

Authors:  A Bauernfeind
Journal:  J Antimicrob Chemother       Date:  1997-11       Impact factor: 5.790

7.  Quinolone-resistant mutants of escherichia coli DNA topoisomerase IV parC gene.

Authors:  Y Kumagai; J I Kato; K Hoshino; T Akasaka; K Sato; H Ikeda
Journal:  Antimicrob Agents Chemother       Date:  1996-03       Impact factor: 5.191

8.  Mutations in the gyrA gene of a highly fluoroquinolone-resistant clinical isolate of Escherichia coli.

Authors:  P Heisig; H Schedletzky; H Falkenstein-Paul
Journal:  Antimicrob Agents Chemother       Date:  1993-04       Impact factor: 5.191

9.  The prevalence of low- and high-level mupirocin resistance in staphylococci from 19 European hospitals.

Authors:  F J Schmitz; E Lindenlauf; B Hofmann; A C Fluit; J Verhoef; H P Heinz; M E Jones
Journal:  J Antimicrob Chemother       Date:  1998-10       Impact factor: 5.790

10.  gyrA mutations associated with fluoroquinolone resistance in eight species of Enterobacteriaceae.

Authors:  L M Weigel; C D Steward; F C Tenover
Journal:  Antimicrob Agents Chemother       Date:  1998-10       Impact factor: 5.191
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  12 in total

1.  Modification of outer membrane protein profile and evidence suggesting an active drug pump in Enterobacter aerogenes clinical strains.

Authors:  Stéphane Gayet; Renaud Chollet; Gérard Molle; Jean-Marie Pagès; Jacqueline Chevalier
Journal:  Antimicrob Agents Chemother       Date:  2003-05       Impact factor: 5.191

2.  Prevalence and role of efflux pump activity in ciprofloxacin resistance in clinical isolates of Klebsiella pneumoniae.

Authors:  S Aathithan; G L French
Journal:  Eur J Clin Microbiol Infect Dis       Date:  2011-02-01       Impact factor: 3.267

3.  Dissemination of ST274 Klebsiella pneumoniae epidemic clone in newborn and adult hospital settings harbouring SHV-2A or CTX-M-15 type extended spectrum β-lactamases-producing known plasmids.

Authors:  I Damjanova; A Tóth; E Kenesei; M Köhalmi; P Szántai; M Füzi; J Pászti
Journal:  Eur J Microbiol Immunol (Bp)       Date:  2011-09-09

4.  Molecular epidemiology of extended-spectrum beta-lactamase-producing, fluoroquinolone-resistant isolates of Klebsiella pneumoniae in Taiwan.

Authors:  W-L Yu; R N Jones; R J Hollis; S A Messer; D J Biedenbach; L M Deshpande; M A Pfaller
Journal:  J Clin Microbiol       Date:  2002-12       Impact factor: 5.948

5.  Klebsiella oxytoca Complex: Update on Taxonomy, Antimicrobial Resistance, and Virulence.

Authors:  Jing Yang; Haiyan Long; Ya Hu; Yu Feng; Alan McNally; Zhiyong Zong
Journal:  Clin Microbiol Rev       Date:  2021-12-01       Impact factor: 50.129

6.  Role of AcrR and ramA in fluoroquinolone resistance in clinical Klebsiella pneumoniae isolates from Singapore.

Authors:  T Schneiders; S G B Amyes; S B Levy
Journal:  Antimicrob Agents Chemother       Date:  2003-09       Impact factor: 5.191

7.  Alteration of GyrA amino acid required for ciprofloxacin resistance in Klebsiella pneumoniae isolates in China.

Authors:  Yingmei Fu; Lishuang Guo; Yan Xu; Wenli Zhang; Jiaao Gu; Jianfeng Xu; Xiaobei Chen; Yuehui Zhao; Jiayu Ma; Xinghan Liu; Fengmin Zhang
Journal:  Antimicrob Agents Chemother       Date:  2008-05-27       Impact factor: 5.191

8.  Specific patterns of gyrA mutations determine the resistance difference to ciprofloxacin and levofloxacin in Klebsiella pneumoniae and Escherichia coli.

Authors:  Yingmei Fu; Wenli Zhang; Hong Wang; Song Zhao; Yang Chen; Fanfei Meng; Ying Zhang; Hui Xu; Xiaobei Chen; Fengmin Zhang
Journal:  BMC Infect Dis       Date:  2013-01-07       Impact factor: 3.090

9.  In vitro activities of 11 fluoroquinolones against 816 non-typhoidal strains of Salmonella enterica isolated from Finnish patients with special reference to reduced ciprofloxacin susceptibility.

Authors:  Pirkko Kotilainen; Susa Pitkänen; Anja Siitonen; Pentti Huovinen; Antti J Hakanen
Journal:  Ann Clin Microbiol Antimicrob       Date:  2005-09-05       Impact factor: 3.944

10.  Resistance determinants and mobile genetic elements of an NDM-1-encoding Klebsiella pneumoniae strain.

Authors:  Corey M Hudson; Zachary W Bent; Robert J Meagher; Kelly P Williams
Journal:  PLoS One       Date:  2014-06-06       Impact factor: 3.240
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