Literature DB >> 2155395

Cloning and sequence analysis of gyrA gene of Klebsiella pneumoniae.

G P Dimri1, H K Das.   

Abstract

The gene gyrA encoding the DNA gyrase A subunit of Klebsiella pneumoniae has been cloned in the plasmid pBR322. Bases of about 3.5 Kb DNA have been sequenced to locate the gyrA gene. An open reading frame of 2628 nucleotides coding for a 97 KD protein has been identified. Homology to the extent of about 85% was detected at the nucleotide level and about 90% at the amino acid level, when the sequences were compared with that of Escherichia coli gyrA. Some very interesting differences have, however, been found in the promoter region.

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Year:  1990        PMID: 2155395      PMCID: PMC330215          DOI: 10.1093/nar/18.1.151

Source DB:  PubMed          Journal:  Nucleic Acids Res        ISSN: 0305-1048            Impact factor:   16.971


  28 in total

1.  DNA gyrase: an enzyme that introduces superhelical turns into DNA.

Authors:  M Gellert; K Mizuuchi; M H O'Dea; H A Nash
Journal:  Proc Natl Acad Sci U S A       Date:  1976-11       Impact factor: 11.205

Review 2.  DNA topoisomerases.

Authors:  M Gellert
Journal:  Annu Rev Biochem       Date:  1981       Impact factor: 23.643

3.  Deoxyribonucleic acid gyrase-deoxyribonucleic acid complex containing 140 base pairs of deoxyribonucleic acid and an alpha 2 beta 2 protein core.

Authors:  L Klevan; J C Wang
Journal:  Biochemistry       Date:  1980-11-11       Impact factor: 3.162

4.  Escherichia coli DNA gyrase.

Authors:  R Otter; N R Cozzarelli
Journal:  Methods Enzymol       Date:  1983       Impact factor: 1.600

5.  Regulation of the genes for E. coli DNA gyrase: homeostatic control of DNA supercoiling.

Authors:  R Menzel; M Gellert
Journal:  Cell       Date:  1983-08       Impact factor: 41.582

6.  Termination of transcription and its regulation in the tryptophan operon of E. coli.

Authors:  T Platt
Journal:  Cell       Date:  1981-04       Impact factor: 41.582

7.  DNA supercoiling and aerobic regulation of transcription from the Klebsiella pneumoniae nifLA promoter.

Authors:  R A Dixon; N C Henderson; S Austin
Journal:  Nucleic Acids Res       Date:  1988-11-11       Impact factor: 16.971

8.  Modulation of gene expression by drugs affecting deoxyribonucleic acid gyrase.

Authors:  B Sanzey
Journal:  J Bacteriol       Date:  1979-04       Impact factor: 3.490

9.  Construction and characterization of new cloning vehicles. II. A multipurpose cloning system.

Authors:  F Bolivar; R L Rodriguez; P J Greene; M C Betlach; H L Heyneker; H W Boyer; J H Crosa; S Falkow
Journal:  Gene       Date:  1977       Impact factor: 3.688

10.  Studies on transformation of Escherichia coli with plasmids.

Authors:  D Hanahan
Journal:  J Mol Biol       Date:  1983-06-05       Impact factor: 5.469

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  30 in total

1.  Sequence analysis of the gyrA and parC homologues of a wild-type strain of Vibrio parahaemolyticus and its fluoroquinolone-resistant mutants.

Authors:  J Okuda; E Hayakawa; M Nishibuchi; T Nishino
Journal:  Antimicrob Agents Chemother       Date:  1999-05       Impact factor: 5.191

2.  4-Quinolone resistance mutations in the DNA gyrase of Escherichia coli clinical isolates identified by using the polymerase chain reaction.

Authors:  M Oram; L M Fisher
Journal:  Antimicrob Agents Chemother       Date:  1991-02       Impact factor: 5.191

3.  Cloning and nucleotide sequence of the DNA gyrase gyrA gene from the fish pathogen Aeromonas salmonicida.

Authors:  H Oppegaard; H Sørum
Journal:  Antimicrob Agents Chemother       Date:  1996-05       Impact factor: 5.191

4.  Diagnosis of quinolone-resistant Coxiella burnetii strains by PCR-RFLP.

Authors:  I Spyridaki; A Psaroulaki; A Aransay; E Scoulica; Y Tselentis
Journal:  J Clin Lab Anal       Date:  2000       Impact factor: 2.352

5.  Sequence analysis, purification, and study of inhibition by 4-quinolones of the DNA gyrase from Mycobacterium smegmatis.

Authors:  V Revel-Viravau; Q C Truong; N Moreau; V Jarlier; W Sougakoff
Journal:  Antimicrob Agents Chemother       Date:  1996-09       Impact factor: 5.191

6.  Cloning, sequencing, and expression of the DNA gyrase genes from Staphylococcus aureus.

Authors:  S M Brockbank; P T Barth
Journal:  J Bacteriol       Date:  1993-06       Impact factor: 3.490

7.  gyrA mutations in quinolone-resistant isolates of the fish pathogen Aeromonas salmonicida.

Authors:  H Oppegaard; H Sørum
Journal:  Antimicrob Agents Chemother       Date:  1994-10       Impact factor: 5.191

8.  Sequence of quinolone resistance-determining region of gyrA gene for clinical isolates and for an in vitro-selected quinolone-resistant strain of Coxiella burnetii.

Authors:  D Musso; M Drancourt; S Osscini; D Raoult
Journal:  Antimicrob Agents Chemother       Date:  1996-04       Impact factor: 5.191

9.  Nucleotide sequence of the gyrA gene and characterization of ciprofloxacin-resistant mutants of Helicobacter pylori.

Authors:  R A Moore; B Beckthold; S Wong; A Kureishi; L E Bryan
Journal:  Antimicrob Agents Chemother       Date:  1995-01       Impact factor: 5.191

Review 10.  Mode of action of the new quinolones: new data.

Authors:  D C Hooper; J S Wolfson
Journal:  Eur J Clin Microbiol Infect Dis       Date:  1991-04       Impact factor: 3.267

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