Literature DB >> 10359693

Multidrug resistance: Versatile drug sensors of bacterial cells.

K Lewis1.   

Abstract

One way that bacteria resist antimicrobial agents involves 'drug sensors', proteins that bind a range of structurally unrelated antimicrobial drugs and induce expression of multidrug resistance pumps. The basis for drug recognition is now becoming clear from the recently determined crystal structure of a drug sensor.

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Year:  1999        PMID: 10359693     DOI: 10.1016/s0960-9822(99)80254-1

Source DB:  PubMed          Journal:  Curr Biol        ISSN: 0960-9822            Impact factor:   10.834


  16 in total

1.  Purification and ligand binding of EmrR, a regulator of a multidrug transporter.

Authors:  A Brooun; J J Tomashek; K Lewis
Journal:  J Bacteriol       Date:  1999-08       Impact factor: 3.490

2.  The staphylococcal QacR multidrug regulator binds a correctly spaced operator as a pair of dimers.

Authors:  S Grkovic; M H Brown; M A Schumacher; R G Brennan; R A Skurray
Journal:  J Bacteriol       Date:  2001-12       Impact factor: 3.490

3.  The EmrR protein represses the Escherichia coli emrRAB multidrug resistance operon by directly binding to its promoter region.

Authors:  A Xiong; A Gottman; C Park; M Baetens; S Pandza; A Matin
Journal:  Antimicrob Agents Chemother       Date:  2000-10       Impact factor: 5.191

4.  Phenothiazinium antimicrobial photosensitizers are substrates of bacterial multidrug resistance pumps.

Authors:  George P Tegos; Michael R Hamblin
Journal:  Antimicrob Agents Chemother       Date:  2006-01       Impact factor: 5.191

5.  Inhibitors of bacterial multidrug efflux pumps potentiate antimicrobial photoinactivation.

Authors:  George P Tegos; Kayo Masago; Fatima Aziz; Andrew Higginbotham; Frank R Stermitz; Michael R Hamblin
Journal:  Antimicrob Agents Chemother       Date:  2008-05-12       Impact factor: 5.191

6.  Photodynamic inactivation of Paracoccidioides brasiliensis helps the outcome of oral paracoccidiodomycosis.

Authors:  Letícia F M Dos Santos; Nathália B Melo; Marina L de Carli; Ana Carolina S C Mendes; Giulia Maria A C Bani; Liana M Verinaud; Eva Burger; Gabriel de Oliveira I Moraes; Alessandro A C Pereira; Maísa R L Brigagão; João Adolfo C Hanemann; Felipe F Sperandio
Journal:  Lasers Med Sci       Date:  2017-03-27       Impact factor: 3.161

7.  Efflux pump inhibitor potentiates antimicrobial photodynamic inactivation of Enterococcus faecalis biofilm.

Authors:  Anil Kishen; Megha Upadya; George P Tegos; Michael R Hamblin
Journal:  Photochem Photobiol       Date:  2010-09-22       Impact factor: 3.421

8.  Potential Antibacterial Targets in Bacterial Central Metabolism.

Authors:  Nichole Louise Haag; Kimberly Kay Velk; Chun Wu
Journal:  Int J Adv Life Sci       Date:  2012

9.  Synergy in a medicinal plant: antimicrobial action of berberine potentiated by 5'-methoxyhydnocarpin, a multidrug pump inhibitor.

Authors:  F R Stermitz; P Lorenz; J N Tawara; L A Zenewicz; K Lewis
Journal:  Proc Natl Acad Sci U S A       Date:  2000-02-15       Impact factor: 11.205

10.  Cannibalism enhances biofilm development in Bacillus subtilis.

Authors:  Daniel López; Hera Vlamakis; Richard Losick; Roberto Kolter
Journal:  Mol Microbiol       Date:  2009-09-22       Impact factor: 3.501

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