Literature DB >> 10209090

RNA splicing: What has phosphorylation got to do with it?

T Misteli1.   

Abstract

Many pre-mRNA splicing factors are phosphorylated in vivo, but the role of this modification has been unclear. Recent observations suggest that phosphorylation modulates protein-protein interactions within the spliceosome, thereby contributing to dynamic structural reorganization of the spliceosome during splicing.

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Substances：

Year:  1999        PMID： 10209090     DOI： 10.1016/s0960-9822(99)80128-6

Source DB:  PubMed          Journal:  Curr Biol        ISSN： 0960-9822            Impact factor:   10.834


  42 in total

1.  Nuclear relocalization of the pre-mRNA splicing factor PSF during apoptosis involves hyperphosphorylation, masking of antigenic epitopes, and changes in protein interactions.

Authors:  Y Shav-Tal; M Cohen; S Lapter; B Dye; J G Patton; J Vandekerckhove; D Zipori
Journal:  Mol Biol Cell       Date:  2001-08       Impact factor: 4.138

2.  Temperature-dependent splicing of beta-globin pre-mRNA.

Authors:  Federica Gemignani; Peter Sazani; Paul Morcos; Ryszard Kole
Journal:  Nucleic Acids Res       Date:  2002-11-01       Impact factor: 16.971

3.  Negative feedback regulation among SR splicing factors encoded by Rbp1 and Rbp1-like in Drosophila.

Authors:  Supriya Kumar; A Javier Lopez
Journal:  EMBO J       Date:  2005-06-16       Impact factor: 11.598

Review 4.  Processive phosphorylation: mechanism and biological importance.

Authors:  Parag Patwardhan; W Todd Miller
Journal:  Cell Signal       Date:  2007-06-22       Impact factor: 4.315

Review 5.  Control of alternative pre-mRNA splicing by Ca(++) signals.

Authors:  Jiuyong Xie
Journal:  Biochim Biophys Acta       Date:  2008-01-17

6.  Growth factor independent 1b (Gfi1b) and a new splice variant of Gfi1b are highly expressed in patients with acute and chronic leukemia.

Authors:  Lothar Vassen; Cyrus Khandanpour; Peter Ebeling; Bert A van der Reijden; Joop H Jansen; Stefan Mahlmann; Ulrich Dührsen; Tarik Möröy
Journal:  Int J Hematol       Date:  2009-04-10       Impact factor: 2.490

7.  A role for ubiquitin in the spliceosome assembly pathway.

Authors:  Priya Bellare; Eliza C Small; Xinhua Huang; James A Wohlschlegel; Jonathan P Staley; Erik J Sontheimer
Journal:  Nat Struct Mol Biol       Date:  2008-04-20       Impact factor: 15.369

8.  Semiquantitative proteomic analysis of the human spliceosome via a novel two-dimensional gel electrophoresis method.

Authors:  Dmitry E Agafonov; Jochen Deckert; Elmar Wolf; Peter Odenwälder; Sergey Bessonov; Cindy L Will; Henning Urlaub; Reinhard Lührmann
Journal:  Mol Cell Biol       Date:  2011-05-02       Impact factor: 4.272

Review 9.  Spliceosome structure and function.

Authors:  Cindy L Will; Reinhard Lührmann
Journal:  Cold Spring Harb Perspect Biol       Date:  2011-07-01       Impact factor: 10.005

Review 10.  S-adenosylmethionine in liver health, injury, and cancer.

Authors:  Shelly C Lu; José M Mato
Journal:  Physiol Rev       Date:  2012-10       Impact factor: 37.312
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