PURPOSE: To determine the clinical feasibility of three-dimensional dynamic contrast agent-enhanced subtraction magnetic resonance (MR) angiography in patients with symptoms of lower extremity ischemia. MATERIALS AND METHODS: Twenty-three patients suspected of having lower extremity ischemia underwent three-dimensional dynamic contrast-enhanced subtraction MR angiography of the aortoiliac arteries and arteries of the lower extremity. As the reference standard, conventional angiography was also performed. For data analysis, the arterial system was divided into 10 segments. Each segment was classified as normal, mildly stenosed, moderately stenosed, severely stenosed, or occluded. RESULTS: At conventional angiography, 83 stenosed segments (14 mildly stenosed, 16 moderately stenosed, 14 severely stenosed, and 39 occluded) were identified in a total of 423 segments. For the segments with more than mild stenosis, MR angiography was 97.1% sensitive and 99.2% specific. CONCLUSION: Three-dimensional dynamic contrast-enhanced subtraction MR angiography has high sensitivity and specificity. This technique is a noninvasive alternative to conventional angiography for screening patients suspected of having lower extremity ischemia.
PURPOSE: To determine the clinical feasibility of three-dimensional dynamic contrast agent-enhanced subtraction magnetic resonance (MR) angiography in patients with symptoms of lower extremity ischemia. MATERIALS AND METHODS: Twenty-three patients suspected of having lower extremity ischemia underwent three-dimensional dynamic contrast-enhanced subtraction MR angiography of the aortoiliac arteries and arteries of the lower extremity. As the reference standard, conventional angiography was also performed. For data analysis, the arterial system was divided into 10 segments. Each segment was classified as normal, mildly stenosed, moderately stenosed, severely stenosed, or occluded. RESULTS: At conventional angiography, 83 stenosed segments (14 mildly stenosed, 16 moderately stenosed, 14 severely stenosed, and 39 occluded) were identified in a total of 423 segments. For the segments with more than mild stenosis, MR angiography was 97.1% sensitive and 99.2% specific. CONCLUSION: Three-dimensional dynamic contrast-enhanced subtraction MR angiography has high sensitivity and specificity. This technique is a noninvasive alternative to conventional angiography for screening patients suspected of having lower extremity ischemia.
Authors: Alex Frydrychowicz; Thorsten A Bley; Jan T Winterer; Andreas Harloff; Mathias Langer; Jürgen Hennig; Michael Markl Journal: MAGMA Date: 2006-08-26 Impact factor: 2.310
Authors: Martin Heuschmid; Benjamin Wiesinger; Gunnar Tepe; Oliver Luz; Andreas F Kopp; Claus D Claussen; Stephan H Duda Journal: Eur Radiol Date: 2006-05-30 Impact factor: 5.315
Authors: Annette Hentsch; Manuela A Aschauer; Jörn O Balzer; Joachim Brossmann; Hans P Busch; Kirsten Davis; Philippe Douek; Franz Ebner; Jos M A van Engelshoven; Michaela Gregor; Christian Kersting; Patrick R Knüsel; Edward Leen; Tim Leiner; Christian Loewe; Simon McPherson; Peter Reimer; Fritz K W Schäfer; Matthias Taupitz; Siegfried A Thurnher; Bernd Tombach; Robin Wegener; Dominik Weishaupt; James F M Meaney Journal: Eur Radiol Date: 2003-03-25 Impact factor: 5.315
Authors: Matthias C Burg; Alexander C Bunck; Harald Seifarth; Boris Buerke; Harald Kugel; Volker Hesselmann; Michael Köhler; Walter Heindel; David Maintz Journal: Radiol Res Pract Date: 2010-07-27