Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 A novel extracellular diterpenoid with antibacterial activity from the cyanobacterium Nostoc commune.

Literature DB >> 10096870

A novel extracellular diterpenoid with antibacterial activity from the cyanobacterium Nostoc commune.

Abstract

A novel extracellular metabolite with an unprecedented diterpenoid skeleton, 8-[(5-carboxy-2-hydroxy)benzyl]-2-hydroxy-1,1,4a,7, 8-pentamethyl-1,2,3,4,4a,6,7,8,8a,9,10,10a-dodecahydrophenanthrene , has been isolated from the culture medium of the terrestrial cyanobacterium Nostoc commune Vaucher (EAWAG 122b) by means of bioguided isolation. The molecule was designated as noscomin. The structure was determined by spectroscopic methods, mainly NMR and mass spectrometry. Noscomin exhibited antibacterial activity against Bacillus cereus, Staphylococcus epidermidis, and Escherichia coli.

Entities: Chemical Species

Mesh：

Substances：

Year: 1999 PMID： 10096870 DOI： 10.1021/np980444x

Source DB: PubMed Journal: J Nat Prod ISSN： 0163-3864 Impact factor: 4.050

Keyword Cloud
Cited

16 in total

1. An antimicrobial guanidine-bearing sesterterpene from the cultured cyanobacterium Scytonema sp.

Authors: Shunyan Mo; Aleksej Krunic; Scott D Pegan; Scott G Franzblau; Jimmy Orjala
Journal: J Nat Prod Date: 2009-11 Impact factor: 4.050

Review 2. Chemodiversity in freshwater and terrestrial cyanobacteria - a source for drug discovery.

Authors: George E Chlipala; Shunyan Mo; Jimmy Orjala
Journal: Curr Drug Targets Date: 2011-10 Impact factor: 3.465

3. 6-Deoxy- and 11-Hydroxytolypodiols: Meroterpenoids from the Cyanobacterium HT-58-2.

Authors: Joshua R Gurr; Timothy J O'Donnell; Yuheng Luo; Wesley Y Yoshida; Mary L Hall; Alejandro M S Mayer; Rui Sun; Philip G Williams
Journal: J Nat Prod Date: 2020-04-13 Impact factor: 4.050

4. Callophycoic acids and callophycols from the Fijian red alga Callophycus serratus.

Authors: Amy L Lane; Elizabeth P Stout; Mark E Hay; Anne C Prusak; Kenneth Hardcastle; Craig R Fairchild; Scott G Franzblau; Karine Le Roch; Jacques Prudhomme; William Aalbersberg; Julia Kubanek
Journal: J Org Chem Date: 2007-08-23 Impact factor: 4.354

5. Antibacterial activity of marine and black band disease cyanobacteria against coral-associated bacteria.

Authors: Miroslav Gantar; Longin T Kaczmarsky; Dina Stanić; Aaron W Miller; Laurie L Richardson
Journal: Mar Drugs Date: 2011-10-24 Impact factor: 6.085

Review 6. Bacterial terpenome.

Authors: Jeffrey D Rudolf; Tyler A Alsup; Baofu Xu; Zining Li
Journal: Nat Prod Rep Date: 2021-05-26 Impact factor: 15.111

A novel extracellular diterpenoid with antibacterial activity from the cyanobacterium Nostoc commune.

1. An antimicrobial guanidine-bearing sesterterpene from the cultured cyanobacterium Scytonema sp.

Review 2. Chemodiversity in freshwater and terrestrial cyanobacteria - a source for drug discovery.

3. 6-Deoxy- and 11-Hydroxytolypodiols: Meroterpenoids from the Cyanobacterium HT-58-2.

4. Callophycoic acids and callophycols from the Fijian red alga Callophycus serratus.

5. Antibacterial activity of marine and black band disease cyanobacteria against coral-associated bacteria.

Review 6. Bacterial terpenome.

Review 7. Cyanobacteria: Photoautotrophic Microbial Factories for the Sustainable Synthesis of Industrial Products.

Review 8. Terpenoids and their biosynthesis in cyanobacteria.

9. The conifer biomarkers dehydroabietic and abietic acids are widespread in Cyanobacteria.

10. Structural Elucidation and Molecular Docking of a Novel Antibiotic Compound from Cyanobacterium Nostoc sp. MGL001.